Photo: Liza Summer

Why you shouldn't drink green tea everyday?

Drinking more than 8 cups of green tea daily is possibly unsafe. Drinking large amounts might cause side effects due to the caffeine content. These side effects can range from mild to serious and include headache and irregular heartbeat.

webmd.com - GREEN TEA: Overview, Uses, Side Effects, Precautions ... - WebMD

What is the best time for eating dark chocolate?

You can enjoy dark chocolates as often as you want. However, for a person who wishes to lose weight with these chocolates, dark chocolates should...

Last updated May 25, 2018

What makes life worth living?

Loving connections with family members, friends and others also make life worth living. Relationships give opportunities to practice love,...

Last updated Oct 20, 2018

Promotion

Adcocks, C., Collin, P., and Buttle, D. J. Catechins from green tea (Camellia sinensis) inhibit bovine and human cartilage proteoglycan and type II collagen degradation in vitro. J Nutr. 2002;132(3):341-346. View abstract. Agarwal, A., Prasad, R., and Jain, A. Effect of green tea extract (catechins) in reducing oxidative stress seen in patients of pulmonary tuberculosis on DOTS Cat I regimen. Phytomedicine. 2010;17(1):23-27. View abstract. Ahmed, S., Wang, N., Lalonde, M., Goldberg, V. M., and Haqqi, T. M. Green tea polyphenol epigallocatechin-3-gallate (EGCG) differentially inhibits interleukin-1 beta-induced expression of matrix metalloproteinase-1 and -13 in human chondrocytes. J Pharmacol.Exp.Ther. 2004;308(2):767-773. View abstract. Al-Sowyan, N. S. Difference in leptin hormone response to nutritional status in normal adult male albino rats. Pak.J Biol.Sci. 1-15-2009;12(2):119-126. View abstract. Alemdaroglu, N. C., Dietz, U., Wolffram, S., Spahn-Langguth, H., and Langguth, P. Influence of green and black tea on folic acid pharmacokinetics in healthy volunteers: potential risk of diminished folic acid bioavailability. Biopharm.Drug Dispos. 2008;29(6):335-348. View abstract. Alexopoulos, N., Vlachopoulos, C., Aznaouridis, K., Baou, K., Vasiliadou, C., Pietri, P., Xaplanteris, P., Stefanadi, E., and Stefanadis, C. The acute effect of green tea consumption on endothelial function in healthy individuals. Eur.J Cardiovasc.Prev.Rehabil. 2008;15(3):300-305. View abstract. Ali, M., Afzal, M., Gubler, C. J., and Burka, J. F. A potent thromboxane formation inhibitor in green tea leaves. Prostaglandins Leukot.Essent.Fatty Acids 1990;40(4):281-283. View abstract. Allen, N. E., Sauvaget, C., Roddam, A. W., Appleby, P., Nagano, J., Suzuki, G., Key, T. J., and Koyama, K. A prospective study of diet and prostate cancer in Japanese men. Cancer Causes Control 2004;15(9):911-920. View abstract. Antonello, M., Montemurro, D., Bolognesi, M., Di, Pascoli M., Piva, A., Grego, F., Sticchi, D., Giuliani, L., Garbisa, S., and Rossi, G. P. Prevention of hypertension, cardiovascular damage and endothelial dysfunction with green tea extracts. Am.J Hypertens. 2007;20(12):1321-1328. View abstract. Arts, I. C. A review of the epidemiological evidence on tea, flavonoids, and lung cancer. J Nutr. 2008;138(8):1561S-1566S. View abstract. Auvichayapat, P., Prapochanung, M., Tunkamnerdthai, O., Sripanidkulchai, B. O., Auvichayapat, N., Thinkhamrop, B., Kunhasura, S., Wongpratoom, S., Sinawat, S., and Hongprapas, P. Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial. Physiol Behav 2-27-2008;93(3):486-491. View abstract. Awadalla, H. I., Ragab, M. H., Bassuoni, M. W., Fayed, M. T., and Abbas, M. O. A pilot study of the role of green tea use on oral health. Int.J.Dent.Hyg. 2011;9(2):110-116. View abstract. Babu, P. V. and Liu, D. Green tea catechins and cardiovascular health: an update. Curr.Med Chem. 2008;15(18):1840-1850. View abstract. Babu, P. V., Sabitha, K. E., Srinivasan, P., and Shyamaladevi, C. S. Green tea attenuates diabetes induced Maillard-type fluorescence and collagen cross-linking in the heart of streptozotocin diabetic rats. Pharmacol.Res. 2007;55(5):433-440. View abstract. Basu, A., Du, M., Sanchez, K., Leyva, M. J., Betts, N. M., Blevins, S., Wu, M., Aston, C. E., and Lyons, T. J. Green tea minimally affects biomarkers of inflammation in obese subjects with metabolic syndrome. Nutrition 2011;27(2):206-213. View abstract. Basu, A., Sanchez, K., Leyva, M. J., Wu, M., Betts, N. M., Aston, C. E., and Lyons, T. J. Green tea supplementation affects body weight, lipids, and lipid peroxidation in obese subjects with metabolic syndrome. J Am.Coll.Nutr. 2010;29(1):31-40. View abstract. Batista, Gde A., Cunha, C. L., Scartezini, M., von der, Heyde R., Bitencourt, M. G., and Melo, S. F. Prospective double-blind crossover study of Camellia sinensis (green tea) in dyslipidemias. Arq Bras.Cardiol. 2009;93(2):128-134. View abstract. Belza, A., Toubro, S., and Astrup, A. The effect of caffeine, green tea and tyrosine on thermogenesis and energy intake. Eur.J Clin Nutr 2009;63(1):57-64. View abstract. Bergman, J. and Schjott, J. Hepatitis caused by Lotus-f3? Basic Clin Pharmacol.Toxicol. 2009;104(5):414-416. View abstract. Bertipaglia de Santana, M., Mandarino, M. G., Cardoso, J. R., Dichi, I., Dichi, J. B., Camargo, A. E., Fabris, B. A., Rodrigues, R. J., Fatel, E. C., Nixdorf, S. L., Simao, A. N., Cecchini, R., and Barbosa, D. S. Association between soy and green tea (Camellia sinensis) diminishes hypercholesterolemia and increases total plasma antioxidant potential in dyslipidemic subjects. Nutrition 2008;24(6):562-568. View abstract. Boehm, K., Borrelli, F., Ernst, E., Habacher, G., Hung, S. K., Milazzo, S., and Horneber, M. Green tea (Camellia sinensis) for the prevention of cancer. Cochrane.Database.Syst.Rev. 2009;(3):CD005004. View abstract. Bogdanski, P., Suliburska, J., Szulinska, M., Stepien, M., Pupek-Musialik, D., and Jablecka, A. Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients. Nutr.Res. 2012;32(6):421-427. View abstract. Brown, A. L., Lane, J., Coverly, J., Stocks, J., Jackson, S., Stephen, A., Bluck, L., Coward, A., and Hendrickx, H. Effects of dietary supplementation with the green tea polyphenol epigallocatechin-3-gallate on insulin resistance and associated metabolic risk factors: randomized controlled trial. Br.J Nutr. 2009;101(6):886-894. View abstract. Brown, A. L., Lane, J., Holyoak, C., Nicol, B., Mayes, A. E., and Dadd, T. Health effects of green tea catechins in overweight and obese men: a randomised controlled cross-over trial. Br.J.Nutr. 2011;106(12):1880-1889. View abstract. Buscemi, S., Verga, S., Batsis, J. A., Donatelli, M., Tranchina, M. R., Belmonte, S., Mattina, A., Re, A., and Cerasola, G. Acute effects of coffee on endothelial function in healthy subjects. Eur.J Clin Nutr. 2010;64(5):483-489. View abstract. Chan, C. C., Koo, M. W., Ng, E. H., Tang, O. S., Yeung, W. S., and Ho, P. C. Effects of Chinese green tea on weight, and hormonal and biochemical profiles in obese patients with polycystic ovary syndrome--a randomized placebo-controlled trial. J Soc Gynecol.Investig. 2006;13(1):63-68. View abstract. Chan, Y. C., Hosoda, K., Tsai, C. J., Yamamoto, S., and Wang, M. F. Favorable effects of tea on reducing the cognitive deficits and brain morphological changes in senescence-accelerated mice. J Nutr.Sci.Vitaminol.(Tokyo) 2006;52(4):266-273. View abstract. Chen, Y. K., Lee, C. H., Wu, I. C., Liu, J. S., Wu, D. C., Lee, J. M., Goan, Y. G., Chou, S. H., Huang, C. T., Lee, C. Y., Hung, H. C., Yang, J. F., and Wu, M. T. Food intake and the occurrence of squamous cell carcinoma in different sections of the esophagus in Taiwanese men. Nutrition 2009;25(7-8):753-761. View abstract. Childs, E. and de, Wit H. Enhanced mood and psychomotor performance by a caffeine-containing energy capsule in fatigued individuals. Exp.Clin Psychopharmacol. 2008;16(1):13-21. View abstract. Chiu, A. E., Chan, J. L., Kern, D. G., Kohler, S., Rehmus, W. E., and Kimball, A. B. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin. Dermatol Surg. 2005;31(7 Pt 2):855-860. View abstract. Choan, E., Segal, R., Jonker, D., Malone, S., Reaume, N., Eapen, L., and Gallant, V. A prospective clinical trial of green tea for hormone refractory prostate cancer: an evaluation of the complementary/alternative therapy approach. Urol.Oncol. 2005;23(2):108-113. View abstract. Choi, J. Y., Park, C. S., Kim, D. J., Cho, M. H., Jin, B. K., Pie, J. E., and Chung, W. G. Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate. Neurotoxicology 2002;23(3):367-374. View abstract. Choi, K. C., Jung, M. G., Lee, Y. H., Yoon, J. C., Kwon, S. H., Kang, H. B., Kim, M. J., Cha, J. H., Kim, Y. J., Jun, W. J., Lee, J. M., and Yoon, H. G. Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation. Cancer Res. 1-15-2009;69(2):583-592. View abstract. Chow, H. H., Cai, Y., Alberts, D. S., Hakim, I., Dorr, R., Shahi, F., Crowell, J. A., Yang, C. S., and Hara, Y. Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E. Cancer Epidemiol.Biomarkers Prev. 2001;10(1):53-58. View abstract. Chow, H. H., Cai, Y., Hakim, I. A., Crowell, J. A., Shahi, F., Brooks, C. A., Dorr, R. T., Hara, Y., and Alberts, D. S. Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals. Clin Cancer Res. 8-15-2003;9(9):3312-3319. View abstract. Chow, H. H., Hakim, I. A., Vining, D. R., Crowell, J. A., Cordova, C. A., Chew, W. M., Xu, M. J., Hsu, C. H., Ranger-Moore, J., and Alberts, D. S. Effects of repeated green tea catechin administration on human cytochrome P450 activity. Cancer Epidemiol.Biomarkers Prev. 2006;15(12):2473-2476. View abstract. Chow, H. H., Hakim, I. A., Vining, D. R., Crowell, J. A., Ranger-Moore, J., Chew, W. M., Celaya, C. A., Rodney, S. R., Hara, Y., and Alberts, D. S. Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals. Clin Cancer Res 6-15-2005;11(12):4627-4633. View abstract. Chroscinska-Krawczyk, M., Ratnaraj, N., Patsalos, P. N., and Czuczwar, S. J. Effect of caffeine on the anticonvulsant effects of oxcarbazepine, lamotrigine and tiagabine in a mouse model of generalized tonic-clonic seizures. Pharmacol Rep. 2009;61(5):819-826. View abstract. Chuarienthong, P., Lourith, N., and Leelapornpisid, P. Clinical efficacy comparison of anti-wrinkle cosmetics containing herbal flavonoids. Int J Cosmet.Sci. 2010;32(2):99-106. View abstract. Ciotta, L., Stracquadanio, M., Formuso, C., Di, Leo S., Ando, A., and Pagano, I. [Clinical effectiveness of N-oleyl-phosphatidyl-ethanolamine (NOPE) in obesity: our experience]. Minerva Gastroenterol.Dietol. 2011;57(3):323-331. View abstract. Clausen, T. Hormonal and pharmacological modification of plasma potassium homeostasis. Fundam.Clin Pharmacol 2010;24(5):595-605. View abstract. Conen, D., Chiuve, S. E., Everett, B. M., Zhang, S. M., Buring, J. E., and Albert, C. M. Caffeine consumption and incident atrial fibrillation in women. Am J Clin Nutr 2010;92(3):509-514. View abstract.

Cronin JR. Green tea extract stokes thermogenesis. Alternative and Complementary Therapies 2000;296-300.

da Costa Santos, C. M., de Mattos Pimenta, C. A., and Nobre, M. R. A systematic review of topical treatments to control the odor of malignant fungating wounds. J Pain Symptom.Manage. 2010;39(6):1065-1076. View abstract. Dagan, Y. and Doljansky, J. T. Cognitive performance during sustained wakefulness: A low dose of caffeine is equally effective as modafinil in alleviating the nocturnal decline. Chronobiol.Int. 2006;23(5):973-983. View abstract. Dalbo, V. J., Roberts, M. D., Stout, J. R., and Kerksick, C. M. Effect of gender on the metabolic impact of a commercially available thermogenic drink. J Strength.Cond.Res 2010;24(6):1633-1642. View abstract. Das, A., Banik, N. L., and Ray, S. K. Flavonoids activated caspases for apoptosis in human glioblastoma T98G and U87MG cells but not in human normal astrocytes. Cancer 1-1-2010;116(1):164-176. View abstract. Del, Rio D., Calani, L., Cordero, C., Salvatore, S., Pellegrini, N., and Brighenti, F. Bioavailability and catabolism of green tea flavan-3-ols in humans. Nutrition 1-14-2010; View abstract. Dell'Aica, I., Dona, M., Tonello, F., Piris, A., Mock, M., Montecucco, C., and Garbisa, S. Potent inhibitors of anthrax lethal factor from green tea. EMBO Rep. 2004;5(4):418-422. View abstract. Devika, P. T. and Stanely Mainzen, Prince P. (-)Epigallocatechin-gallate (EGCG) prevents mitochondrial damage in isoproterenol-induced cardiac toxicity in albino Wistar rats: a transmission electron microscopic and in vitro study. Pharmacol.Res. 2008;57(5):351-357. View abstract. Di, Pierro F., Menghi, A. B., Barreca, A., Lucarelli, M., and Calandrelli, A. Greenselect Phytosome as an adjunct to a low-calorie diet for treatment of obesity: a clinical trial. Altern.Med Rev. 2009;14(2):154-160. View abstract. Diepvens, K., Kovacs, E. M., Vogels, N., and Westerterp-Plantenga, M. S. Metabolic effects of green tea and of phases of weight loss. Physiol Behav 1-30-2006;87(1):185-191. View abstract. Donovan, J. L., Devane, C. L., Chavin, K. D., Oates, J. C., Njoku, C., Patrick, K. S., Fiorini, R. N., and Markowitz, J. S. Oral administration of a decaffeinated green tea (Camellia sinensis) extract did not alter urinary 8-epi-prostaglandin F(2 alpha), a biomarker for in-vivo lipid peroxidation. J Pharm Pharmacol 2005;57(10):1365-1369. View abstract. Du, X., Huang, X., Huang, C., Wang, Y., and Zhang, Y. Epigallocatechin-3-gallate (EGCG) enhances the therapeutic activity of a dental adhesive. J.Dent. 2012;40(6):485-492. View abstract. Dufresne CJ and Farnworth ER. A review of latest research findings on the health promotion properties of tea. Journal of Nutritional Biochemistry 2001;12:404-421. Dulloo, A. G. and Miller, D. S. The thermogenic properties of ephedrine/methylxanthine mixtures: animal studies. Am J Clin Nutr 1986;43(3):388-394. View abstract. Dulloo, A. G., Seydoux, J., Girardier, L., Chantre, P., and Vandermander, J. Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity. Int J Obes.Relat Metab Disord. 2000;24(2):252-258. View abstract. Dunne, E. F., Friedman, A., Datta, S. D., Markowitz, L. E., and Workowski, K. A. Updates on human papillomavirus and genital warts and counseling messages from the 2010 Sexually Transmitted Diseases Treatment Guidelines. Clin.Infect.Dis. 2011;53 Suppl 3:S143-S152. View abstract. Eichenberger, P., Colombani, P. C., and Mettler, S. Effects of 3-week consumption of green tea extracts on whole-body metabolism during cycling exercise in endurance-trained men. Int J Vitam.Nutr.Res. 2009;79(1):24-33. View abstract. Eichenberger, P., Mettler, S., Arnold, M., and Colombani, P. C. No effects of three-week consumption of a green tea extract on time trial performance in endurance-trained men. Int J Vitam.Nutr.Res. 2010;80(1):54-64. View abstract. Engdal, S. and Nilsen, O. G. In vitro inhibition of CYP3A4 by herbal remedies frequently used by cancer patients. Phytother.Res. 2009;23(7):906-912. View abstract. Erba, D., Riso, P., Bordoni, A., Foti, P., Biagi, P. L., and Testolin, G. Effectiveness of moderate green tea consumption on antioxidative status and plasma lipid profile in humans. J Nutr Biochem 2005;16(3):144-149. View abstract. Ernest, D., Chia, M., and Corallo, C. E. Profound hypokalaemia due to Nurofen Plus and Red Bull misuse. Crit Care Resusc. 2010;12(2):109-110. View abstract. Favreau, J. T., Ryu, M. L., Braunstein, G., Orshansky, G., Park, S. S., Coody, G. L., Love, L. A., and Fong, T. L. Severe hepatotoxicity associated with the dietary supplement LipoKinetix. Ann.Intern.Med. 4-16-2002;136(8):590-595. View abstract. Federico, A., Tiso, A., and Loguercio, C. A case of hepatotoxicity caused by green tea. Free Radic.Biol Med 8-1-2007;43(3):474. View abstract. Frank, J., George, T. W., Lodge, J. K., Rodriguez-Mateos, A. M., Spencer, J. P., Minihane, A. M., and Rimbach, G. Daily consumption of an aqueous green tea extract supplement does not impair liver function or alter cardiovascular disease risk biomarkers in healthy men. J Nutr 2009;139(1):58-62. View abstract. Freese, R., Basu, S., Hietanen, E., Nair, J., Nakachi, K., Bartsch, H., and Mutanen, M. Green tea extract decreases plasma malondialdehyde concentration but does not affect other indicators of oxidative stress, nitric oxide production, or hemostatic factors during a high-linoleic acid diet in healthy females. Eur.J Nutr. 1999;38(3):149-157. View abstract. Fukino, Y., Ikeda, A., Maruyama, K., Aoki, N., Okubo, T., and Iso, H. Randomized controlled trial for an effect of green tea-extract powder supplementation on glucose abnormalities. Eur.J Clin Nutr 2008;62(8):953-960. View abstract. Fukino, Y., Shimbo, M., Aoki, N., Okubo, T., and Iso, H. Randomized controlled trial for an effect of green tea consumption on insulin resistance and inflammation markers. J Nutr Sci Vitaminol.(Tokyo) 2005;51(5):335-342. View abstract. Fukushima, Y., Ohie, T., Yonekawa, Y., Yonemoto, K., Aizawa, H., Mori, Y., Watanabe, M., Takeuchi, M., Hasegawa, M., Taguchi, C., and Kondo, K. Coffee and green tea as a large source of antioxidant polyphenols in the Japanese population. J Agric.Food Chem. 2-25-2009;57(4):1253-1259. View abstract. Gao, Y. T., McLaughlin, J. K., Blot, W. J., Ji, B. T., Dai, Q., and Fraumeni, J. F., Jr. Reduced risk of esophageal cancer associated with green tea consumption. J Natl.Cancer Inst. 6-1-1994;86(11):855-858. View abstract. Gawande, S., Kale, A., and Kotwal, S. Effect of nutrient mixture and black grapes on the pharmacokinetics of orally administered (-)epigallocatechin-3-gallate from green tea extract: a human study. Phytother.Res. 2008;22(6):802-808. View abstract. Gregersen, N. T., Bitz, C., Krog-Mikkelsen, I., Hels, O., Kovacs, E. M., Rycroft, J. A., Frandsen, E., Mela, D. J., and Astrup, A. Effect of moderate intakes of different tea catechins and caffeine on acute measures of energy metabolism under sedentary conditions. Br.J Nutr. 2009;102(8):1187-1194. View abstract. Gronroos, N. N. and Alonso, A. Diet and risk of atrial fibrillation - epidemiologic and clinical evidence -. Circ.J 2010;74(10):2029-2038. View abstract. Gross, G. [Polyphenon E. A new topical therapy for condylomata acuminata]. Hautarzt 2008;59(1):31-35. View abstract. Gross, G., Meyer, K. G., Pres, H., Thielert, C., Tawfik, H., and Mescheder, A. A randomized, double-blind, four-arm parallel-group, placebo-controlled Phase II/III study to investigate the clinical efficacy of two galenic formulations of Polyphenon E in the treatment of external genital warts. J Eur.Acad.Dermatol.Venereol. 2007;21(10):1404-1412. View abstract. Hakim, I. A., Chow, H. H., and Harris, R. B. Green tea consumption is associated with decreased DNA damage among GSTM1-positive smokers regardless of their hOGG1 genotype. J Nutr. 2008;138(8):1567S-1571S. View abstract. Hakim, I. A., Harris, R. B., Brown, S., Chow, H. H., Wiseman, S., Agarwal, S., and Talbot, W. Effect of increased tea consumption on oxidative DNA damage among smokers: a randomized controlled study. J.Nutr. 2003;133(10):3303S-3309S. View abstract. Hakim, I. A., Harris, R. B., Chow, H. H., Dean, M., Brown, S., and Ali, I. U. Effect of a 4-month tea intervention on oxidative DNA damage among heavy smokers: role of glutathione S-transferase genotypes. Cancer Epidemiol.Biomarkers Prev. 2004;13(2):242-249. View abstract. Haque, A. M., Hashimoto, M., Katakura, M., Tanabe, Y., Hara, Y., and Shido, O. Long-term administration of green tea catechins improves spatial cognition learning ability in rats. J Nutr. 2006;136(4):1043-1047. View abstract. Hasani-Ranjbar, S., Nayebi, N., Moradi, L., Mehri, A., Larijani, B., and Abdollahi, M. The efficacy and safety of herbal medicines used in the treatment of hyperlipidemia; a systematic review. Curr.Pharm.Des 2010;16(26):2935-2947. View abstract. Hatano, B., Kojima, A., Sata, T., and Katano, H. Virus detection using Viro-Adembeads, a rapid capture system for viruses, and plaque assay in intentionally virus-contaminated beverages. Jpn.J Infect.Dis. 2010;63(1):52-54. View abstract. Hattori, M., Kusumoto, I. T., Namba, T., Ishigami, T., and Hara, Y. Effect of tea polyphenols on glucan synthesis by glucosyltransferase from Streptococcus mutans. Chem.Pharm Bull.(Tokyo) 1990;38(3):717-720. View abstract. Hauber, I., Hohenberg, H., Holstermann, B., Hunstein, W., and Hauber, J. The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection. Proc.Natl.Acad.Sci.U.S.A 6-2-2009;106(22):9033-9038. View abstract. He, Y. H. and Kies, C. Green and black tea consumption by humans: impact on polyphenol concentrations in feces, blood and urine. Plant Foods Hum.Nutr. 1994;46(3):221-229. View abstract. Heinrich, U., Moore, C. E., De, Spirt S., Tronnier, H., and Stahl, W. Green tea polyphenols provide photoprotection, increase microcirculation, and modulate skin properties of women. J.Nutr. 2011;141(6):1202-1208. View abstract. Hemelt, M., Hu, Z., Zhong, Z., Xie, L. P., Wong, Y. C., Tam, P. C., Cheng, K. K., Ye, Z., Bi, X., Lu, Q., Mao, Y., Zhong, W. D., and Zeegers, M. P. Fluid intake and the risk of bladder cancer: results from the South and East China case-control study on bladder cancer. Int.J.Cancer 8-1-2010;127(3):638-645. View abstract. Henning, S. M., Aronson, W., Niu, Y., Conde, F., Lee, N. H., Seeram, N. P., Lee, R. P., Lu, J., Harris, D. M., Moro, A., Hong, J., Pak-Shan, L., Barnard, R. J., Ziaee, H. G., Csathy, G., Go, V. L., Wang, H., and Heber, D. Tea polyphenols and theaflavins are present in prostate tissue of humans and mice after green and black tea consumption. J Nutr 2006;136(7):1839-1843. View abstract. Henning, S. M., Niu, Y., Lee, N. H., Thames, G. D., Minutti, R. R., Wang, H., Go, V. L., and Heber, D. Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement. Am J Clin Nutr 2004;80(6):1558-1564. View abstract. Henrotin, Y., Lambert, C., Couchourel, D., Ripoll, C., and Chiotelli, E. Nutraceuticals: do they represent a new era in the management of osteoarthritis? - a narrative review from the lessons taken with five products. Osteoarthritis.Cartilage. 2011;19(1):1-21. View abstract. Hirano, R., Momiyama, Y., Takahashi, R., Taniguchi, H., Kondo, K., Nakamura, H., and Ohsuzu, F. Comparison of green tea intake in Japanese patients with and without angiographic coronary artery disease. Am.J Cardiol. 11-15-2002;90(10):1150-1153. View abstract. Hirano-Ohmori, R., Takahashi, R., Momiyama, Y., Taniguchi, H., Yonemura, A., Tamai, S., Umegaki, K., Nakamura, H., Kondo, K., and Ohsuzu, F. Green tea consumption and serum malondialdehyde-modified LDL concentrations in healthy subjects. J Am Coll.Nutr 2005;24(5):342-346. View abstract. Hirao, K., Yumoto, H., Nakanishi, T., Mukai, K., Takahashi, K., Takegawa, D., and Matsuo, T. Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells. Life Sci. 4-24-2010;86(17-18):654-660. View abstract. Hirasawa, M., Takada, K., Makimura, M., and Otake, S. Improvement of periodontal status by green tea catechin using a local delivery system: a clinical pilot study. J Periodontal Res 2002;37(6):433-438. View abstract. Horiba, N., Maekawa, Y., Ito, M., Matsumoto, T., and Nakamura, H. A pilot study of Japanese green tea as a medicament: antibacterial and bactericidal effects. J Endod. 1991;17(3):122-124. View abstract. Hsu, C. H., Liao, Y. L., Lin, S. C., Tsai, T. H., Huang, C. J., and Chou, P. Does supplementation with green tea extract improve insulin resistance in obese type 2 diabetics? A randomized, double-blind, and placebo-controlled clinical trial. Altern.Med.Rev. 2011;16(2):157-163. View abstract. Hsu, C. H., Tsai, T. H., Kao, Y. H., Hwang, K. C., Tseng, T. Y., and Chou, P. Effect of green tea extract on obese women: a randomized, double-blind, placebo-controlled clinical trial. Clin Nutr 2008;27(3):363-370. View abstract. Hsu, J., Skover, G., and Goldman, M. P. Evaluating the efficacy in improving facial photodamage with a mixture of topical antioxidants. J Drugs Dermatol. 2007;6(11):1141-1148. View abstract. Hunt, K. J., Hung, S. K., and Ernst, E. Botanical extracts as anti-aging preparations for the skin: a systematic review. Drugs Aging 12-1-2010;27(12):973-985. View abstract. Hursel, R. and Westerterp-Plantenga, M. S. Green tea catechin plus caffeine supplementation to a high-protein diet has no additional effect on body weight maintenance after weight loss. Am J Clin Nutr 2009;89(3):822-830. View abstract. Ichinose, T., Nomura, S., Someya, Y., Akimoto, S., Tachiyashiki, K., and Imaizumi, K. Effect of endurance training supplemented with green tea extract on substrate metabolism during exercise in humans. Scand.J Med Sci.Sports 3-10-2010; View abstract. Imai, K., Suga, K., and Nakachi, K. Cancer-preventive effects of drinking green tea among a Japanese population. Prev.Med 1997;26(6):769-775. View abstract. Inami, S., Takano, M., Yamamoto, M., Murakami, D., Tajika, K., Yodogawa, K., Yokoyama, S., Ohno, N., Ohba, T., Sano, J., Ibuki, C., Seino, Y., and Mizuno, K. Tea catechin consumption reduces circulating oxidized low-density lipoprotein. Int Heart J 2007;48(6):725-732. View abstract. Inoue, M., Robien, K., Wang, R., Van Den Berg, D. J., Koh, W. P., and Yu, M. C. Green tea intake, MTHFR/TYMS genotype and breast cancer risk: the Singapore Chinese Health Study. Carcinogenesis 2008;29(10):1967-1972. View abstract. Izzo, A. A. and Ernst, E. Interactions between herbal medicines and prescribed drugs: an updated systematic review. Drugs 2009;69(13):1777-1798. View abstract. Janjua, R., Munoz, C., Gorell, E., Rehmus, W., Egbert, B., Kern, D., and Chang, A. L. A two-year, double-blind, randomized placebo-controlled trial of oral green tea polyphenols on the long-term clinical and histologic appearance of photoaging skin. Dermatol.Surg. 2009;35(7):1057-1065. View abstract. Jankun, J., Selman, S. H., Swiercz, R., and Skrzypczak-Jankun, E. Why drinking green tea could prevent cancer. Nature 6-5-1997;387(6633):561. View abstract. Javaid, A. and Bonkovsky, H. L. Hepatotoxicity due to extracts of Chinese green tea (Camellia sinensis): a growing concern. J Hepatol 2006;45(2):334-335. View abstract. Ji, B. T., Chow, W. H., Hsing, A. W., McLaughlin, J. K., Dai, Q., Gao, Y. T., Blot, W. J., and Fraumeni, J. F., Jr. Green tea consumption and the risk of pancreatic and colorectal cancers. Int J Cancer 1-27-1997;70(3):255-258. View abstract. Jin, X., Zheng, R. H., and Li, Y. M. Green tea consumption and liver disease: a systematic review. Liver Int 2008;28(7):990-996. View abstract. Josic, J., Olsson, A. T., Wickeberg, J., Lindstedt, S., and Hlebowicz, J. Does green tea affect postprandial glucose, insulin and satiety in healthy subjects: a randomized controlled trial. Nutr.J. 2010;9:63. View abstract. Jowko, E., Sacharuk, J., Balasinska, B., Ostaszewski, P., Charmas, M., and Charmas, R. Green tea extract supplementation gives protection against exercise-induced oxidative damage in healthy men. Nutr.Res. 2011;31(11):813-821. View abstract. Jurgens, T. M., Whelan, A. M., Killian, L., Doucette, S., Kirk, S., and Foy, E. Green tea for weight loss and weight maintenance in overweight or obese adults. Cochrane.Database.Syst.Rev. 2012;12:CD008650. View abstract. Kakuta, Y., Nakaya, N., Nagase, S., Fujita, M., Koizumi, T., Okamura, C., Niikura, H., Ohmori, K., Kuriyama, S., Tase, T., Ito, K., Minami, Y., Yaegashi, N., and Tsuji, I. Case-control study of green tea consumption and the risk of endometrial endometrioid adenocarcinoma. Cancer Causes Control 2009;20(5):617-624. View abstract. Kalus, U., Kiesewetter, H., and Radtke, H. Effect of CYSTUS052 and green tea on subjective symptoms in patients with infection of the upper respiratory tract. Phytother.Res. 2010;24(1):96-100. View abstract. Karth, A., Holoshitz, N., Kavinsky, C. J., Trohman, R., and McBride, B. F. A case report of atrial fibrillation potentially induced by hydroxycut: a multicomponent dietary weight loss supplement devoid of sympathomimetic amines. J.Pharm.Pract. 2010;23(3):245-249. View abstract. Katiyar, S. K., Matsui, M. S., Elmets, C. A., and Mukhtar, H. Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin. Photochem.Photobiol. 1999;69(2):148-153. View abstract. Kato, M. T., Leite, A. L., Hannas, A. R., and Buzalaf, M. A. Gels containing MMP inhibitors prevent dental erosion in situ. J Dent.Res. 2010;89(5):468-472. View abstract. Key, T. J., Sharp, G. B., Appleby, P. N., Beral, V., Goodman, M. T., Soda, M., and Mabuchi, K. Soya foods and breast cancer risk: a prospective study in Hiroshima and Nagasaki, Japan. Br J Cancer 1999;81(7):1248-1256. View abstract. Kikuchi, N., Ohmori, K., Shimazu, T., Nakaya, N., Kuriyama, S., Nishino, Y., Tsubono, Y., and Tsuji, I. No association between green tea and prostate cancer risk in Japanese men: the Ohsaki Cohort Study. Br.J Cancer 8-7-2006;95(3):371-373. View abstract. Kim, W., Jeong, M. H., Cho, S. H., Yun, J. H., Chae, H. J., Ahn, Y. K., Lee, M. C., Cheng, X., Kondo, T., Murohara, T., and Kang, J. C. Effect of green tea consumption on endothelial function and circulating endothelial progenitor cells in chronic smokers. Circ.J 2006;70(8):1052-1057. View abstract. Kohler, M., Pavy, A., and van den Heuvel, C. The effects of chewing versus caffeine on alertness, cognitive performance and cardiac autonomic activity during sleep deprivation. J Sleep Res. 2006;15(4):358-368. View abstract. Komatsu, T., Nakamori, M., Komatsu, K., Hosoda, K., Okamura, M., Toyama, K., Ishikura, Y., Sakai, T., Kunii, D., and Yamamoto, S. Oolong tea increases energy metabolism in Japanese females. J Med Invest 2003;50(3-4):170-175. View abstract. Kristen, A. V., Lehrke, S., Buss, S., Mereles, D., Steen, H., Ehlermann, P., Hardt, S., Giannitsis, E., Schreiner, R., Haberkorn, U., Schnabel, P. A., Linke, R. P., Rocken, C., Wanker, E. E., Dengler, T. J., Altland, K., and Katus, H. A. Green tea halts progression of cardiac transthyretin amyloidosis: an observational report. Clin.Res.Cardiol. 2012;101(10):805-813. View abstract. Kuo, Y. C., Yu, C. L., Liu, C. Y., Wang, S. F., Pan, P. C., Wu, M. T., Ho, C. K., Lo, Y. S., Li, Y., and Christiani, D. C. A population-based, case-control study of green tea consumption and leukemia risk in southwestern Taiwan. Cancer Causes Control 2009;20(1):57-65. View abstract. Kurahashi, N., Inoue, M., Iwasaki, M., Sasazuki, S., and Tsugane, S. Coffee, green tea, and caffeine consumption and subsequent risk of bladder cancer in relation to smoking status: a prospective study in Japan. Cancer Sci. 2009;100(2):294-91. View abstract. Kurahashi, N., Sasazuki, S., Iwasaki, M., Inoue, M., and Tsugane, S. Green tea consumption and prostate cancer risk in Japanese men: a prospective study. Am J Epidemiol. 1-1-2008;167(1):71-77. View abstract. Kuriyama, S. The relation between green tea consumption and cardiovascular disease as evidenced by epidemiological studies. J Nutr. 2008;138(8):1548S-1553S. View abstract. Kushima, Y., Iida, K., Nagaoka, Y., Kawaratani, Y., Shirahama, T., Sakaguchi, M., Baba, K., Hara, Y., and Uesato, S. Inhibitory effect of (-)-epigallocatechin and (-)-epigallocatechin gallate against heregulin beta1-induced migration/invasion of the MCF-7 breast carcinoma cell line. Biol.Pharm.Bull. 2009;32(5):899-904. View abstract. Kushiyama, M., Shimazaki, Y., Murakami, M., and Yamashita, Y. Relationship between intake of green tea and periodontal disease. J Periodontol. 2009;80(3):372-377. View abstract. Lang, M., Henson, R., Braconi, C., and Patel, T. Epigallocatechin-gallate modulates chemotherapy-induced apoptosis in human cholangiocarcinoma cells. Liver Int 2009;29(5):670-677. View abstract. Langley, P. C. A cost-effectiveness analysis of sinecatechins in the treatment of external genital warts. J.Med.Econ. 2010;13(1):1-7. View abstract. Laurie, S. A., Miller, V. A., Grant, S. C., Kris, M. G., and Ng, K. K. Phase I study of green tea extract in patients with advanced lung cancer. Cancer Chemother.Pharmacol. 2005;55(1):33-38. View abstract. Levites, Y., Amit, T., Mandel, S., and Youdim, M. B. Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate. FASEB J 2003;17(8):952-954. View abstract. Li, G. X., Chen, Y. K., Hou, Z., Xiao, H., Jin, H., Lu, G., Lee, M. J., Liu, B., Guan, F., Yang, Z., Yu, A., and Yang, C. S. Pro-oxidative activities and dose-response relationship of (-)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro. Carcinogenesis 2010;31(5):902-910. View abstract. Li, R., Huang, Y. G., Fang, D., and Le, W. D. (-)-Epigallocatechin gallate inhibits lipopolysaccharide-induced microglial activation and protects against inflammation-mediated dopaminergic neuronal injury. J Neurosci.Res. 12-1-2004;78(5):723-731. View abstract. Liatsos, G. D., Moulakakis, A., Ketikoglou, I., and Klonari, S. Possible green tea-induced thrombotic thrombocytopenic purpura. Am.J Health Syst.Pharm. 4-1-2010;67(7):531-534. View abstract. Lin, C. L., Chen, T. F., Chiu, M. J., Way, T. D., and Lin, J. K. Epigallocatechin gallate (EGCG) suppresses beta-amyloid-induced neurotoxicity through inhibiting c-Abl/FE65 nuclear translocation and GSK3 beta activation. Neurobiol.Aging 2009;30(1):81-92. View abstract. Lonac, M. C., Richards, J. C., Schweder, M. M., Johnson, T. K., and Bell, C. Influence of Short-Term Consumption of the Caffeine-Free, Epigallocatechin-3-Gallate Supplement, Teavigo, on Resting Metabolism and the Thermic Effect of Feeding. Obesity.(Silver.Spring) 8-19-2010; View abstract. Lopez-Garcia, E., Rodriguez-Artalejo, F., Rexrode, K. M., Logroscino, G., Hu, F. B., and van Dam, R. M. Coffee consumption and risk of stroke in women. Circulation 3-3-2009;119(8):1116-1123. View abstract.

Does prostate removal decrease life expectancy?

After 23 years the men treated with radical prostatectomy gained a mean of 2.9 extra years of life. The researchers found that the absolute benefit...

Last updated Nov 9, 2019

Is it better to shave your balls hard or soft?

It's important to stretch your ball skin while shaving it. That way, the skin will be taut — as opposed to soft and shriveled — which makes for a...

Last updated Jul 10, 2022

Promotion

MacKenzie, T., Comi, R., Sluss, P., Keisari, R., Manwar, S., Kim, J., Larson, R., and Baron, J. A. Metabolic and hormonal effects of caffeine: randomized, double-blind, placebo-controlled crossover trial. Metabolism 2007;56(12):1694-1698. View abstract. Maeda-Yamamoto, M., Ema, K., Monobe, M., Shibuichi, I., Shinoda, Y., Yamamoto, T., and Fujisawa, T. The efficacy of early treatment of seasonal allergic rhinitis with benifuuki green tea containing O-methylated catechin before pollen exposure: an open randomized study. Allergol.Int 2009;58(3):437-444. View abstract. Magalhaes, A. C., Wiegand, A., Rios, D., Hannas, A., Attin, T., and Buzalaf, M. A. Chlorhexidine and green tea extract reduce dentin erosion and abrasion in situ. J Dent. 2009;37(12):994-998. View abstract. Mahmood, T., Akhtar, N., Khan, B. A., Shoaib Khan, H. M., and Saeed, T. Changes in skin mechanical properties after long-term application of cream containing green tea extract. Aging Clin.Exp.Res. 2011;23(5-6):333-336. View abstract. Maki, K. C., Reeves, M. S., Farmer, M., Yasunaga, K., Matsuo, N., Katsuragi, Y., Komikado, M., Tokimitsu, I., Wilder, D., Jones, F., Blumberg, J. B., and Cartwright, Y. Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults. J Nutr 2009;139(2):264-270. View abstract. Mangine, G. T., Gonzalez, A. M., Wells, A. J., McCormack, W. P., Fragala, M. S., Stout, J. R., and Hoffman, J. R. The effect of a dietary supplement (N-oleyl-phosphatidyl-ethanolamine and epigallocatechin gallate) on dietary compliance and body fat loss in adults who are overweight: a double-blind, randomized control trial. Lipids Health Dis. 2012;11:127. View abstract. Martinez-Sierra, C., Rendon, Unceta P., and Martin, Herrera L. [Acute hepatitis after green tea ingestion]. Med Clin (Barc.) 6-17-2006;127(3):119. View abstract. Matsumoto, K., Yamada, H., Takuma, N., Niino, H., and Sagesaka, Y. M. Effects of green tea catechins and theanine on preventing influenza infection among healthcare workers: a randomized controlled trial. BMC.Complement Altern.Med. 2011;11:15. View abstract. Matsuyama, T., Tanaka, Y., Kamimaki, I., Nagao, T., and Tokimitsu, I. Catechin safely improved higher levels of fatness, blood pressure, and cholesterol in children. Obesity.(Silver.Spring) 2008;16(6):1338-1348. View abstract. Melgarejo, E., Medina, M. A., Sanchez-Jimenez, F., and Urdiales, J. L. Epigallocatechin gallate reduces human monocyte mobility and adhesion in vitro. Br.J Pharmacol. 2009;158(7):1705-1712. View abstract. Meltzer, S. M., Monk, B. J., and Tewari, K. S. Green tea catechins for treatment of external genital warts. Am J Obstet.Gynecol. 2009;200(3):233-237. View abstract. Miller, R. J., Jackson, K. G., Dadd, T., Mayes, A. E., Brown, A. L., and Minihane, A. M. The impact of the catechol-O-methyltransferase genotype on the acute responsiveness of vascular reactivity to a green tea extract. Br.J.Nutr. 2011;105(8):1138-1144. View abstract. Miller, R. J., Jackson, K. G., Dadd, T., Mayes, A. E., Brown, A. L., Lovegrove, J. A., and Minihane, A. M. The impact of the catechol-O-methyltransferase genotype on vascular function and blood pressure after acute green tea ingestion. Mol.Nutr.Food Res. 2012;56(6):966-975. View abstract. Miller, R. J., Jackson, K. G., Dadd, T., Nicol, B., Dick, J. L., Mayes, A. E., Brown, A. L., and Minihane, A. M. A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins. Eur.J.Nutr. 2012;51(1):47-55. View abstract. Mineharu, Y., Koizumi, A., Wada, Y., Iso, H., Watanabe, Y., Date, C., Yamamoto, A., Kikuchi, S., Inaba, Y., Toyoshima, H., Kondo, T., and Tamakoshi, A. Coffee, green tea, black tea and oolong tea consumption and risk of mortality from cardiovascular disease in Japanese men and women. J Epidemiol.Community Health 7-14-2010; View abstract. Mnich, C. D., Hoek, K. S., Virkki, L. V., Farkas, A., Dudli, C., Laine, E., Urosevic, M., and Dummer, R. Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls. Exp Dermatol. 2009;18(1):69-77. View abstract. Moisey, L. L., Robinson, L. E., and Graham, T. E. Consumption of caffeinated coffee and a high carbohydrate meal affects postprandial metabolism of a subsequent oral glucose tolerance test in young, healthy males. Br.J Nutr. 2010;103(6):833-841. View abstract. Molinari, M., Watt, K. D., Kruszyna, T., Nelson, R., Walsh, M., Huang, W. Y., Nashan, B., and Peltekian, K. Acute liver failure induced by green tea extracts: case report and review of the literature. Liver Transpl. 2006;12(12):1892-1895. View abstract. Mou, N. Z, Ren, G. L., Mou, L. H., and Lu, C. T. Reasearch on the influence of catechin on fatty liver disease (in Chinese). Shandong J Traditional Chin Med 1998;17:55-56. Mu, D., Yu, J. X., and Li, D. Obervation on the therapeutic effect in the treatment of 26 patients with fatty liver by tea pigment capsules (in Chinese). J Norman Bethune Univ Med Sci 1997;23:528-530. Mu, L. N., Zhou, X. F., Ding, B. G., and Wang, R. H. Study on the protective effect of preen tea on gastric, liver and esophageal cancer (in Chinese). Chin J Prev Med 2003;37:171-173. Mukoyama, A., Ushijima, H., Nishimura, S., Koike, H., Toda, M., Hara, Y., and Shimamura, T. Inhibition of rotavirus and enterovirus infections by tea extracts. Jpn.J Med.Sci Biol. 1991;44(4):181-186. View abstract. Mulder, T. P., Rietveld, A. G., and Van Amelsvoort, J. M. Consumption of both black tea and green tea results in an increase in the excretion of hippuric acid into urine. Am.J.Clin Nutr. 2005;81(1 Suppl):256S-260S. View abstract. Muller, N., Ellinger, S., Alteheld, B., Ulrich-Merzenich, G., Berthold, H. K., Vetter, H., and Stehle, P. Bolus ingestion of white and green tea increases the concentration of several flavan-3-ols in plasma, but does not affect markers of oxidative stress in healthy non-smokers. Mol.Nutr.Food Res. 6-10-2010; View abstract. Myung, S. K., Bae, W. K., Oh, S. M., Kim, Y., Ju, W., Sung, J., Lee, Y. J., Ko, J. A., Song, J. I., and Choi, H. J. Green tea consumption and risk of stomach cancer: a meta-analysis of epidemiologic studies. Int J Cancer 2-1-2009;124(3):670-677. View abstract. Nagano, J., Kono, S., Preston, D. L., and Mabuchi, K. A prospective study of green tea consumption and cancer incidence, Hiroshima and Nagasaki (Japan). Cancer Causes Control 2001;12(6):501-508. View abstract. Nagano, J., Kono, S., Preston, D. L., Moriwaki, H., Sharp, G. B., Koyama, K., and Mabuchi, K. Bladder-cancer incidence in relation to vegetable and fruit consumption: a prospective study of atomic-bomb survivors. Int J Cancer 4-1-2000;86(1):132-138. View abstract. Nagao, T., Hase, T., and Tokimitsu, I. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity.(Silver.Spring) 2007;15(6):1473-1483. View abstract. Nagao, T., Komine, Y., Soga, S., Meguro, S., Hase, T., Tanaka, Y., and Tokimitsu, I. Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men. Am J Clin Nutr 2005;81(1):122-129. View abstract. Nagao, T., Meguro, S., Hase, T., Otsuka, K., Komikado, M., Tokimitsu, I., Yamamoto, T., and Yamamoto, K. A catechin-rich beverage improves obesity and blood glucose control in patients with type 2 diabetes. Obesity.(Silver.Spring) 2009;17(2):310-317. View abstract. Nagata, C., Kabuto, M., and Shimizu, H. Association of coffee, green tea, and caffeine intakes with serum concentrations of estradiol and sex hormone-binding globulin in premenopausal Japanese women. Nutr Cancer 1998;30(1):21-24. View abstract. Nakachi, K., Matsuyama, S., Miyake, S., Suganuma, M., and Imai, K. Preventive effects of drinking green tea on cancer and cardiovascular disease: epidemiological evidence for multiple targeting prevention. Biofactors 2000;13(1-4):49-54. View abstract. Nakachi, K., Suemasu, K., Suga, K., Takeo, T., Imai, K., and Higashi, Y. Influence of drinking green tea on breast cancer malignancy among Japanese patients. Jpn J Cancer Res 1998;89(3):254-261. View abstract. Nakagawa, K., Okuda, S., and Miyazawa, T. Dose-dependent incorporation of tea catechins, (-)-epigallocatechin-3- gallate and (-)-epigallocatechin, into human plasma. Biosci.Biotechnol.Biochem 1997;61(12):1981-1985. View abstract. Nakayama, M., Suzuki, K., Toda, M., Okubo, S., Hara, Y., and Shimamura, T. Inhibition of the infectivity of influenza virus by tea polyphenols. Antiviral Res. 1993;21(4):289-299. View abstract. Nance, C. L., Siwak, E. B., and Shearer, W. T. Preclinical development of the green tea catechin, epigallocatechin gallate, as an HIV-1 therapy. J Allergy Clin Immunol. 2009;123(2):459-465. View abstract. Nantz, M. P., Rowe, C. A., Bukowski, J. F., and Percival, S. S. Standardized capsule of Camellia sinensis lowers cardiovascular risk factors in a randomized, double-blind, placebo-controlled study. Nutrition 2009;25(2):147-154. View abstract. Netsch, M. I., Gutmann, H., Schmidlin, C. B., Aydogan, C., and Drewe, J. Induction of CYP1A by green tea extract in human intestinal cell lines. Planta Med 2006;72(6):514-520. View abstract. Nguyen, M. M., Ahmann, F. R., Nagle, R. B., Hsu, C. H., Tangrea, J. A., Parnes, H. L., Sokoloff, M. H., Gretzer, M. B., and Chow, H. H. Randomized, double-blind, placebo-controlled trial of polyphenon E in prostate cancer patients before prostatectomy: evaluation of potential chemopreventive activities. Cancer Prev.Res.(Phila) 2012;5(2):290-298. View abstract. Ogunleye, A. A., Xue, F., and Michels, K. B. Green tea consumption and breast cancer risk or recurrence: a meta-analysis. Breast Cancer Res.Treat. 2010;119(2):477-484. View abstract. Okada, N., Tanabe, H., Tazoe, H., Ishigami, Y., Fukutomi, R., Yasui, K., and Isemura, M. Differentiation-associated alteration in sensitivity to apoptosis induced by (-)-epigallocatechin-3-O-gallate in HL-60 cells. Biomed.Res. 2009;30(4):201-206. View abstract. Orozco-Gregorio, H., Mota-Rojas, D., Bonilla-Jaime, H., Trujillo-Ortega, M. E., Becerril-Herrera, M., Hernandez-Gonzalez, R., and Villanueva-Garcia, D. Effects of administration of caffeine on metabolic variables in neonatal pigs with peripartum asphyxia. Am.J Vet.Res. 2010;71(10):1214-1219. View abstract. Osterburg, A., Gardner, J., Hyon, S. H., Neely, A., and Babcock, G. Highly antibiotic-resistant Acinetobacter baumannii clinical isolates are killed by the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG). Clin Microbiol.Infect. 2009;15(4):341-346. View abstract. Ostrowska, J. and Skrzydlewska, E. The comparison of effect of catechins and green tea extract on oxidative modification of LDL in vitro. Adv Med Sci 2006;51:298-303. View abstract. Otake, S., Makimura, M., Kuroki, T., Nishihara, Y., and Hirasawa, M. Anticaries effects of polyphenolic compounds from Japanese green tea. Caries Res 1991;25(6):438-443. View abstract. Otera, H., Tada, K., Sakurai, T., Hashimoto, K., and Ikeda, A. Hypersensitivity pneumonitis associated with inhalation of catechin-rich green tea extracts. Respiration 2011;82(4):388-392. View abstract. Oyama, J., Maeda, T., Kouzuma, K., Ochiai, R., Tokimitsu, I., Higuchi, Y., Sugano, M., and Makino, N. Green tea catechins improve human forearm endothelial dysfunction and have antiatherosclerotic effects in smokers. Circ.J 2010;74(3):578-588. View abstract. Oyama, J., Maeda, T., Sasaki, M., Kozuma, K., Ochiai, R., Tokimitsu, I., Taguchi, S., Higuchi, Y., and Makino, N. Green tea catechins improve human forearm vascular function and have potent anti-inflammatory and anti-apoptotic effects in smokers. Intern.Med. 2010;49(23):2553-2559. View abstract. Pan, T., Fei, J., Zhou, X., Jankovic, J., and Le, W. Effects of green tea polyphenols on dopamine uptake and on MPP+ -induced dopamine neuron injury. Life Sci. 1-17-2003;72(9):1073-1083. View abstract. Panza, V. S., Wazlawik, E., Ricardo, Schutz G., Comin, L., Hecht, K. C., and da Silva, E. L. Consumption of green tea favorably affects oxidative stress markers in weight-trained men. Nutrition 2008;24(5):433-442. View abstract. Papparella, I., Ceolotto, G., Montemurro, D., Antonello, M., Garbisa, S., Rossi, G., and Semplicini, A. Green tea attenuates angiotensin II-induced cardiac hypertrophy in rats by modulating reactive oxygen species production and the Src/epidermal growth factor receptor/Akt signaling pathway. J Nutr. 2008;138(9):1596-1601. View abstract. Park, C. S., Kim, W., Woo, J. S., Ha, S. J., Kang, W. Y., Hwang, S. H., Park, Y. W., Kim, Y. S., Ahn, Y. K., Jeong, M. H., and Kim, W. Green tea consumption improves endothelial function but not circulating endothelial progenitor cells in patients with chronic renal failure. Int J Cardiol. 12-2-2009; View abstract. Park, M., Yamada, H., Matsushita, K., Kaji, S., Goto, T., Okada, Y., Kosuge, K., and Kitagawa, T. Green tea consumption is inversely associated with the incidence of influenza infection among schoolchildren in a tea plantation area of Japan. J.Nutr. 2011;141(10):1862-1870. View abstract. Park, S. K., Jung, I. C., Lee, W. K., Lee, Y. S., Park, H. K., Go, H. J., Kim, K., Lim, N. K., Hong, J. T., Ly, S. Y., and Rho, S. S. A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study. J.Med.Food 2011;14(4):334-343. View abstract. Pavel, L. and Pave, S. [Usefulness of micronutrients in the treatment of periodontitis]. Ned.Tijdschr.Tandheelkd. 2010;117(2):103-106. [RETRACTED]. View abstract. Pecorari, M., Villano, D., Testa, M. F., Schmid, M., and Serafini, M. Biomarkers of antioxidant status following ingestion of green teas at different polyphenol concentrations and antioxidant capacity in human volunteers. Mol.Nutr.Food Res. 2010;54 Suppl 2:S278-S283. View abstract. Perera, V., Gross, A. S., and McLachlan, A. J. Caffeine and paraxanthine HPLC assay for CYP1A2 phenotype assessment using saliva and plasma. Biomed.Chromatogr. 2010;24(10):1136-1144. View abstract. Pietta, P., Simonetti, P., Gardana, C., Brusamolino, A., Morazzoni, P., and Bombardelli, E. Relationship between rate and extent of catechin absorption and plasma antioxidant status. Biochem Mol.Biol Int. 1998;46(5):895-903. View abstract. Rasheed, Z., Anbazhagan, A. N., Akhtar, N., Ramamurthy, S., Voss, F. R., and Haqqi, T. M. Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-alpha and matrix metalloproteinase-13 in human chondrocytes. Arthritis Res.Ther. 2009;11(3):R71. View abstract. Reis, J. P., Loria, C. M., Steffen, L. M., Zhou, X., van, Horn L., Siscovick, D. S., Jacobs, D. R., Jr., and Carr, J. J. Coffee, decaffeinated coffee, caffeine, and tea consumption in young adulthood and atherosclerosis later in life: the CARDIA study. Arterioscler.Thromb.Vasc.Biol 2010;30(10):2059-2066. View abstract. Renouf, M., Guy, P., Marmet, C., Longet, K., Fraering, A. L., Moulin, J., Barron, D., Dionisi, F., Cavin, C., Steiling, H., and Williamson, G. Plasma appearance and correlation between coffee and green tea metabolites in human subjects. Br.J Nutr. 8-9-2010;1-6. View abstract. Richards, J. C., Lonac, M. C., Johnson, T. K., Schweder, M. M., and Bell, C. Epigallocatechin-3-gallate Increases Maximal Oxygen Uptake in Adult Humans. Med Sci.Sports Exerc. 11-27-2009; View abstract. Rigato, I., Blarasin, L., and Kette, F. Severe hypokalemia in 2 young bicycle riders due to massive caffeine intake. Clin J Sport Med. 2010;20(2):128-130. View abstract. Rizvi, S. I., Jha, R., and Pandey, K. B. Activation of erythrocyte plasma membrane redox system provides a useful method to evaluate antioxidant potential of plant polyphenols. Methods Mol.Biol. 2010;594:341-348. View abstract. Rohde, J., Jacobsen, C., and Kromann-Andersen, H. [Toxic hepatitis triggered by green tea]. Ugeskr.Laeger 1-17-2011;173(3):205-206. View abstract. Rondanelli, M., Opizzi, A., Solerte, S. B., Trotti, R., Klersy, C., and Cazzola, R. Administration of a dietary supplement ( N-oleyl-phosphatidylethanolamine and epigallocatechin-3-gallate formula) enhances compliance with diet in healthy overweight subjects: a randomized controlled trial. Br.J.Nutr. 2009;101(3):457-464. View abstract. Roomi, M. W., Monterrey, J. C., Kalinovsky, T., Rath, M., and Niedzwiecki, A. Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines. Oncol.Rep. 2010;24(3):747-757. View abstract. Rosenbaum, C. C., O'Mathuna, D. P., Chavez, M., and Shields, K. Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis. Altern.Ther.Health Med. 2010;16(2):32-40. View abstract. Rowe, C. A., Nantz, M. P., Bukowski, J. F., and Percival, S. S. Specific formulation of Camellia sinensis prevents cold and flu symptoms and enhances gamma,delta T cell function: a randomized, double-blind, placebo-controlled study. J Am Coll.Nutr 2007;26(5):445-452. View abstract. Ruhl, C. E. and Everhart, J. E. Coffee and tea consumption are associated with a lower incidence of chronic liver disease in the United States. Gastroenterology 2005;129(6):1928-1936. View abstract. Ryu, O. H., Lee, J., Lee, K. W., Kim, H. Y., Seo, J. A., Kim, S. G., Kim, N. H., Baik, S. H., Choi, D. S., and Choi, K. M. Effects of green tea consumption on inflammation, insulin resistance and pulse wave velocity in type 2 diabetes patients. Diabetes Res.Clin Pract. 2006;71(3):356-358. View abstract. Sagesaka-Mitane, Y., Miwa, M., and Okada, S. Platelet aggregation inhibitors in hot water extract of green tea. Chem Pharm Bull.(Tokyo) 1990;38(3):790-793. View abstract. Sakamoto, O., Saita, N., Yamasaki, H., Tamanoi, M., and Ando, M. Pulmonary granulomatosis caused by aspirated green tea. Chest 1994;106(1):308-309. View abstract. Sarma, D. N., Barrett, M. L., Chavez, M. L., Gardiner, P., Ko, R., Mahady, G. B., Marles, R. J., Pellicore, L. S., Giancaspro, G. I., and Low, Dog T. Safety of green tea extracts : a systematic review by the US Pharmacopeia. Drug Saf 2008;31(6):469-484. View abstract. Sasazuki, S., Kodama, H., Yoshimasu, K., Liu, Y., Washio, M., Tanaka, K., Tokunaga, S., Kono, S., Arai, H., Doi, Y., Kawano, T., Nakagaki, O., Takada, K., Koyanagi, S., Hiyamuta, K., Nii, T., Shirai, K., Ideishi, M., Arakawa, K., Mohri, M., and Takeshita, A. Relation between green tea consumption and the severity of coronary atherosclerosis among Japanese men and women. Ann.Epidemiol. 2000;10(6):401-408. View abstract. Sato, Y., Nakatsuka, H., Watanabe, T., Hisamichi, S., Shimizu, H., Fujisaku, S., Ichinowatari, Y., Ida, Y., Suda, S., Kato, K., and . Possible contribution of green tea drinking habits to the prevention of stroke. Tohoku J Exp Med 1989;157(4):337-343. View abstract. Scholey, A., Downey, L. A., Ciorciari, J., Pipingas, A., Nolidin, K., Finn, M., Wines, M., Catchlove, S., Terrens, A., Barlow, E., Gordon, L., and Stough, C. Acute neurocognitive effects of epigallocatechin gallate (EGCG). Appetite 2012;58(2):767-770. View abstract. Serafini, M., Ghiselli, A., and Ferro-Luzzi, A. In vivo antioxidant effect of green and black tea in man. Eur.J Clin Nutr. 1996;50(1):28-32. View abstract. Severson, R. K., Nomura, A. M., Grove, J. S., and Stemmermann, G. N. A prospective study of demographics, diet, and prostate cancer among men of Japanese ancestry in Hawaii. Cancer Res. 4-1-1989;49(7):1857-1860. View abstract. Shanafelt, T. D., Call, T. G., Zent, C. S., LaPlant, B., Bowen, D. A., Roos, M., Secreto, C. R., Ghosh, A. K., Kabat, B. F., Lee, M. J., Yang, C. S., Jelinek, D. F., Erlichman, C., and Kay, N. E. Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia. J Clin Oncol. 8-10-2009;27(23):3808-3814. View abstract. Shanafelt, T. D., Call, T. G., Zent, C. S., Leis, J. F., LaPlant, B., Bowen, D. A., Roos, M., Laumann, K., Ghosh, A. K., Lesnick, C., Lee, M. J., Yang, C. S., Jelinek, D. F., Erlichman, C., and Kay, N. E. Phase 2 trial of daily, oral Polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia. Cancer 1-15-2013;119(2):363-370. View abstract. Shen, C. L., Chyu, M. C., Pence, B. C., Yeh, J. K., Zhang, Y., Felton, C. K., Doctolero, S., and Wang, J. S. Green tea polyphenols supplementation and Tai Chi exercise for postmenopausal osteopenic women: safety and quality of life report. BMC.Complement Altern.Med. 2010;10:76. View abstract. Shen, C. L., Chyu, M. C., Yeh, J. K., Felton, C. K., Xu, K. T., Pence, B. C., and Wang, J. S. Green tea polyphenols and Tai Chi for bone health: designing a placebo-controlled randomized trial. BMC.Musculoskelet.Disord. 2009;10:110. View abstract. Shen, C. L., Chyu, M. C., Yeh, J. K., Zhang, Y., Pence, B. C., Felton, C. K., Brismee, J. M., Arjmandi, B. H., Doctolero, S., and Wang, J. S. Effect of green tea and Tai Chi on bone health in postmenopausal osteopenic women: a 6-month randomized placebo-controlled trial. Osteoporos.Int. 2012;23(5):1541-1552. View abstract. Shen, H. B., Xu, Y. C., Shen, J., and Niu, J. Y. The relationship between habit of drinking green tea and primary liver cancer:a case control study (in Chinese). Clin J Behav Med Sci 1996;5:588-589. Shim, J. S., Kang, M. H., Kim, Y. H., Roh, J. K., Roberts, C., and Lee, I. P. Chemopreventive effect of green tea (Camellia sinensis) among cigarette smokers. Cancer Epidemiol Biomarkers Prev 1995;4(4):387-391. View abstract. Shimizu, M., Fukutomi, Y., Ninomiya, M., Nagura, K., Kato, T., Araki, H., Suganuma, M., Fujiki, H., and Moriwaki, H. Green tea extracts for the prevention of metachronous colorectal adenomas: a pilot study. Cancer Epidemiol.Biomarkers Prev. 2008;17(11):3020-3025. View abstract. Shin, D. M. Oral cancer prevention advances with a translational trial of green tea. Cancer Prev.Res.(Phila Pa) 2009;2(11):919-921. View abstract. Shrubsole, M. J., Lu, W., Chen, Z., Shu, X. O., Zheng, Y., Dai, Q., Cai, Q., Gu, K., Ruan, Z. X., Gao, Y. T., and Zheng, W. Drinking green tea modestly reduces breast cancer risk. J Nutr. 2009;139(2):310-316. View abstract. Simmonds, M. J., Minahan, C. L., and Sabapathy, S. Caffeine improves supramaximal cycling but not the rate of anaerobic energy release. Eur.J Appl Physiol 2010;109(2):287-295. View abstract. Singh, R., Ahmed, S., Islam, N., Goldberg, V. M., and Haqqi, T. M. Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factor kappaB. Arthritis Rheum. 2002;46(8):2079-2086. View abstract. Singh, R., Ahmed, S., Malemud, C. J., Goldberg, V. M., and Haqqi, T. M. Epigallocatechin-3-gallate selectively inhibits interleukin-1beta-induced activation of mitogen activated protein kinase subgroup c-Jun N-terminal kinase in human osteoarthritis chondrocytes. J Orthop.Res. 2003;21(1):102-109. View abstract. Slivova, V., Zaloga, G., DeMichele, S. J., Mukerji, P., Huang, Y. S., Siddiqui, R., Harvey, K., Valachovicova, T., and Sliva, D. Green tea polyphenols modulate secretion of urokinase plasminogen activator (uPA) and inhibit invasive behavior of breast cancer cells. Nutr Cancer 2005;52(1):66-73. View abstract. Smits, P., Temme, L., and Thien, T. The cardiovascular interaction between caffeine and nicotine in humans. Clin Pharmacol Ther 1993;54(2):194-204. View abstract. Snider, J. Green tea may promote periodontal health. J Am.Dent.Assoc. 2009;140(7):838. View abstract. Somani, S. M. and Gupta, P. Caffeine: a new look at an age-old drug. Int.J.Clin.Pharmacol.Ther.Toxicol. 1988;26(11):521-533. View abstract. Sommer, A. P. and Zhu, D. Green tea and red light--a powerful duo in skin rejuvenation. Photomed.Laser Surg. 2009;27(6):969-971. View abstract. Sonoda, J., Koriyama, C., Yamamoto, S., Kozako, T., Li, H. C., Lema, C., Yashiki, S., Fujiyoshi, T., Yoshinaga, M., Nagata, Y., Akiba, S., Takezaki, T., Yamada, K., and Sonoda, S. HTLV-1 provirus load in peripheral blood lymphocytes of HTLV-1 carriers is diminished by green tea drinking. Cancer Sci 2004;95(7):596-601. View abstract. Stendell-Hollis, N. R., Thomson, C. A., Thompson, P. A., Bea, J. W., Cussler, E. C., and Hakim, I. A. Green tea improves metabolic biomarkers, not weight or body composition: a pilot study in overweight breast cancer survivors. J.Hum.Nutr.Diet. 2010;23(6):590-600. View abstract. Stingl, J. C., Ettrich, T., Muche, R., Wiedom, M., Brockmoller, J., Seeringer, A., and Seufferlein, T. Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population. BMC.Cancer 2011;11:360. View abstract. Stockfleth, E., Beti, H., Orasan, R., Grigorian, F., Mescheder, A., Tawfik, H., and Thielert, C. Topical Polyphenon E in the treatment of external genital and perianal warts: a randomized controlled trial. Br.J Dermatol. 2008;158(6):1329-1338. View abstract. Subramaniam, P., Eswara, U., and Maheshwar Reddy, K. R. Effect of different types of tea on Streptococcus mutans: an in vitro study. Indian J.Dent.Res. 2012;23(1):43-48. View abstract. Sun, C. L., Yuan, J. M., Koh, W. P., and Yu, M. C. Green tea, black tea and colorectal cancer risk: a meta-analysis of epidemiologic studies. Carcinogenesis 2006;27(7):1301-1309. View abstract. Sung, H., Min, W. K., Lee, W., Chun, S., Park, H., Lee, Y. W., Jang, S., and Lee, D. H. The effects of green tea ingestion over four weeks on atherosclerotic markers. Ann.Clin Biochem 2005;42(Pt 4):292-297. View abstract. Suyama, E., Tamura, T., Ozawa, T., Suzuki, A., Iijima, Y., and Saito, T. Remineralization and acid resistance of enamel lesions after chewing gum containing fluoride extracted from green tea. Aust.Dent.J. 2011;56(4):394-400. View abstract. Syed TA, Ahmad SA. Wong W. et al. Clinical evaluation of 2 polyphenone (green tea extract) in a hydrophilic gel to assess improvement in aged and damaged facial skin: a placebo-controlled, double-blind study [abstract]. 20th Worid Congress of Dermatology; 2002;1. Takeshita M, Takashima S Harada U Shibata E Hosoya N Takase H et al. Effects of long-term consumption of tea catechins-enriched beverage with no caffeine on body composition in humans. Japanese Pharmacology and Therapeutics 2008;36(8):767-776. Tang, N. P., Li, H., Qiu, Y. L., Zhou, G. M., and Ma, J. Tea consumption and risk of endometrial cancer: a metaanalysis. Am.J Obstet.Gynecol. 2009;201(6):605-608. View abstract. Tang, N., Wu, Y., Zhou, B., Wang, B., and Yu, R. Green tea, black tea consumption and risk of lung cancer: a meta-analysis. Lung Cancer 2009;65(3):274-283. View abstract. Tao M, Liu D Gao L Jin F. Association between green tea drinking and breast cancer risk. Tumor 2002;22(3):11-15. Tatti, S., Stockfleth, E., Beutner, K. R., Tawfik, H., Elsasser, U., Weyrauch, P., and Mescheder, A. Polyphenon E: a new treatment for external anogenital warts. Br.J Dermatol. 2010;162(1):176-184. View abstract. Tatti, S., Swinehart, J. M., Thielert, C., Tawfik, H., Mescheder, A., and Beutner, K. R. Sinecatechins, a defined green tea extract, in the treatment of external anogenital warts: a randomized controlled trial. Obstet.Gynecol. 2008;111(6):1371-1379. View abstract. Tjeerdsma, F., Jonkman, M. F., and Spoo, J. R. Temporary arrest of basal cell carcinoma formation in a patient with basal cell naevus syndrome (BCNS) since treatment with a gel containing various plant extracts. J.Eur.Acad.Dermatol.Venereol. 2011;25(2):244-245. View abstract. Tomankova, K., Kolarova, H., Bajgar, R., Jirova, D., Kejlova, K., and Mosinger, J. Study of the photodynamic effect on the A549 cell line by atomic force microscopy and the influence of green tea extract on the production of reactive oxygen species. Ann.N.Y.Acad.Sci. 2009;1171:549-558. View abstract. Tsao, A. S., Liu, D., Martin, J., Tang, X. M., Lee, J. J., El-Naggar, A. K., Wistuba, I., Culotta, K. S., Mao, L., Gillenwater, A., Sagesaka, Y. M., Hong, W. K., and Papadimitrakopoulou, V. Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions. Cancer Prev.Res.(Phila Pa) 2009;2(11):931-941. View abstract. Tsubono Y and Tsugane S. Green tea intake in relation to serum lipid levels in middle-aged japanese men and women. Ann Epidemiol 1997;7(4):280-284. Tzellos, T. G., Sardeli, C., Lallas, A., Papazisis, G., Chourdakis, M., and Kouvelas, D. Efficacy, safety and tolerability of green tea catechins in the treatment of external anogenital warts: a systematic review and meta-analysis. J.Eur.Acad.Dermatol.Venereol. 2011;25(3):345-353. View abstract. Ullmann, U., Haller, J., Decourt, J. D., Girault, J., Spitzer, V., and Weber, P. Plasma-kinetic characteristics of purified and isolated green tea catechin epigallocatechin gallate (EGCG) after 10 days repeated dosing in healthy volunteers. Int J Vitam.Nutr.Res. 2004;74(4):269-278. View abstract. Unno, T., Kondo, K., Itakura, H., and Takeo, T. Analysis of (-)-epigallocatechin gallate in human serum obtained after ingesting green tea. Biosci.Biotechnol.Biochem 1996;60(12):2066-2068. View abstract. Unno, T., Tago, M., Suzuki, Y., Nozawa, A., Sagesaka, Y. M., Kakuda, T., Egawa, K., and Kondo, K. Effect of tea catechins on postprandial plasma lipid responses in human subjects. Br.J Nutr. 2005;93(4):543-547. View abstract. Van Dorsten, F. A., Daykin, C. A., Mulder, T. P., and Van Duynhoven, J. P. Metabonomics approach to determine metabolic differences between green tea and black tea consumption. J Agric Food Chem 9-6-2006;54(18):6929-6938. View abstract. Van Het Hof, K. H., de Boer, H. S., Wiseman, S. A., Lien, N., Westrate, J. A., and Tijburg, L. B. Consumption of green or black tea does not increase resistance of low-density lipoprotein to oxidation in humans. Am.J Clin.Nutr. 1997;66(5):1125-1132. View abstract. Van Het Hof, K. H., Kivits, G. A., Weststrate, J. A., and Tijburg, L. B. Bioavailability of catechins from tea: the effect of milk. Eur.J Clin.Nutr. 1998;52(5):356-359. View abstract. Van Het Hof, K. H., Wiseman, S. A., Yang, C. S., and Tijburg, L. B. Plasma and lipoprotein levels of tea catechins following repeated tea consumption. Proc.Soc.Exp.Biol.Med 1999;220(4):203-209. View abstract. Venables, M. C., Hulston, C. J., Cox, H. R., and Jeukendrup, A. E. Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans. Am.J Clin Nutr. 2008;87(3):778-784. View abstract. Vu, H. A., Beppu, Y., Chi, H. T., Sasaki, K., Yamamoto, H., Xinh, P. T., Tanii, T., Hara, Y., Watanabe, T., Sato, Y., and Ohdomari, I. Green tea epigallocatechin gallate exhibits anticancer effect in human pancreatic carcinoma cells via the inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor. J.Biomed.Biotechnol. 2010;2010:290516. View abstract. Wakai, K., Hirose, K., Takezaki, T., Hamajima, N., Ogura, Y., Nakamura, S., Hayashi, N., and Tajima, K. Foods and beverages in relation to urothelial cancer: case-control study in Japan. Int J Urol. 2004;11(1):11-19. View abstract. Wang, H., Wen, Y., Du, Y., Yan, X., Guo, H., Rycroft, J. A., Boon, N., Kovacs, E. M., and Mela, D. J. Effects of catechin enriched green tea on body composition. Obesity.(Silver.Spring) 2010;18(4):773-779. View abstract. Wang, L. D., Zhou, Q., Feng, C. W., Liu, B., Qi, Y. J., Zhang, Y. R., Gao, S. S., Fan, Z. M., Zhou, Y., Yang, C. S., Wei, J. P., and Zheng, S. Intervention and follow-up on human esophageal precancerous lesions in Henan, northern China, a high-incidence area for esophageal cancer. Gan To Kagaku Ryoho 2002;29 Suppl 1:159-172. View abstract. Wang, L., Xu, S., Xu, X., and Chan, P. (-)-Epigallocatechin-3-Gallate protects SH-SY5Y cells against 6-OHDA-induced cell death through STAT3 activation. J.Alzheimers.Dis. 2009;17(2):295-304. View abstract. Wang, P., Aronson, W. J., Huang, M., Zhang, Y., Lee, R. P., Heber, D., and Henning, S. M. Green tea polyphenols and metabolites in prostatectomy tissue: implications for cancer prevention. Cancer Prev.Res.(Phila Pa) 2010;3(8):985-993. View abstract. Wang, Q. M., Gong, Q. Y., Yan, J. J., Zhu, J., Tang, J. J., Wang, M. W., Yang, Z. J., and Wang, L. S. Association between green tea intake and coronary artery disease in a Chinese population. Circ.J 2010;74(2):294-300. View abstract. Wang, Z. M., Zhou, B., Wang, Y. S., Gong, Q. Y., Wang, Q. M., Yan, J. J., Gao, W., and Wang, L. S. Black and green tea consumption and the risk of coronary artery disease: a meta-analysis. Am.J.Clin.Nutr. 2011;93(3):506-515. View abstract.

Can saw palmetto increase PSA?

Some studies suggest that saw palmetto is equally effective for reducing BPH symptoms as Proscar, and it has one meaningful advantage: It leaves...

Last updated Mar 27, 2022

Does removing prostate get rid of cancer?

Surgery can cure prostate cancer if the disease hasn't spread outside of the prostate gland. The most common procedure is a radical prostatectomy....

Last updated May 21, 2019

Promotion

Watanabe, I., Kuriyama, S., Kakizaki, M., Sone, T., Ohmori-Matsuda, K., Nakaya, N., Hozawa, A., and Tsuji, I. Green tea and death from pneumonia in Japan: the Ohsaki cohort study. Am.J Clin Nutr. 2009;90(3):672-679. View abstract. Wen, W., Xiang, Y. B., Zheng, W., Xu, W. H., Yang, G., Li, H., and Shu, X. O. The association of alcohol, tea, and other modifiable lifestyle factors with myocardial infarction and stroke in Chinese men. CVD.Prev Control 2008;3(3):133-140. View abstract. Westphal, L. M., Polan, M. L., and Trant, A. S. Double-blind, placebo-controlled study of Fertilityblend: a nutritional supplement for improving fertility in women. Clin Exp.Obstet.Gynecol. 2006;33(4):205-208. View abstract. Wightman, E. L., Haskell, C. F., Forster, J. S., Veasey, R. C., and Kennedy, D. O. Epigallocatechin gallate, cerebral blood flow parameters, cognitive performance and mood in healthy humans: a double-blind, placebo-controlled, crossover investigation. Hum.Psychopharmacol. 2012;27(2):177-186. View abstract. Wilkens, L. R., Kadir, M. M., Kolonel, L. N., Nomura, A. M., and Hankin, J. H. Risk factors for lower urinary tract cancer: the role of total fluid consumption, nitrites and nitrosamines, and selected foods. Cancer Epidemiol.Biomarkers Prev. 1996;5(3):161-166. View abstract. Williamson, G., Coppens, P., Serra-Majem, L., and Dew, T. Review of the efficacy of green tea, isoflavones and aloe vera supplements based on randomised controlled trials. Food Funct. 2011;2(12):753-759. View abstract. Wu, A. H., Spicer, D., Stanczyk, F. Z., Tseng, C. C., Yang, C. S., and Pike, M. C. Effect of 2-month controlled green tea intervention on lipoprotein cholesterol, glucose, and hormone levels in healthy postmenopausal women. Cancer Prev.Res.(Phila) 2012;5(3):393-402. View abstract. Wu, H., Zhu, B., Shimoishi, Y., Murata, Y., and Nakamura, Y. (-)-Epigallocatechin-3-gallate induces up-regulation of Th1 and Th2 cytokine genes in Jurkat T cells. Arch.Biochem.Biophys. 3-1-2009;483(1):99-105. View abstract. Wu, M., Liu, A. M., Kampman, E., Zhang, Z. F., Van't Veer, P., Wu, D. L., Wang, P. H., Yang, J., Qin, Y., Mu, L. N., Kok, F. J., and Zhao, J. K. Green tea drinking, high tea temperature and esophageal cancer in high- and low-risk areas of Jiangsu Province, China: a population-based case-control study. Int J Cancer 4-15-2009;124(8):1907-1913. View abstract. Wu, S., Li, F., Huang, X., Hua, Q., Huang, T., Liu, Z., Liu, Z., Zhang, Z., Liao, C., Chen, Y., Shi, Y., Zeng, R., Feng, M., Zhong, X., Long, Z., Tan, W., and Zhang, X. The association of tea consumption with bladder cancer risk: a meta-analysis. Asia Pac.J.Clin.Nutr. 2013;22(1):128-137. View abstract. Wu, Y. J., Liang, C. H., Zhou, F. J., Gao, X., Chen, L. W., and Liu, Q. [A case-control study of environmental and genetic factors and prostate cancer in Guangdong]. Zhonghua Yu Fang Yi.Xue.Za Zhi. 2009;43(7):581-585. View abstract. Xiao, J. P., Shen, X. N., Wu, M., and Lu, R. F. Epidemiologic survey on the association between green tea intake and fatty liver disease (in Chinese). China Public Health 2002;18:385-387. Xu, H., Becker, C. M., Lui, W. T., Chu, C. Y., Davis, T. N., Kung, A. L., Birsner, A. E., D'Amato, R. J., Wai Man, G. C., and Wang, C. C. Green tea epigallocatechin-3-gallate inhibits angiogenesis and suppresses vascular endothelial growth factor C/vascular endothelial growth factor receptor 2 expression and signaling in experimental endometriosis in vivo. Fertil.Steril. 2011;96(4):1021-1028. View abstract. Xu, Y. C., Shen, H. B., Niu, J. Y., and Shen, J. An intervention trial with green tea on high risk population of primary liver cancer (in Chinese). Cancer Res Prev Treatment 1998;25:223-225. Yang, C. S., Chen, L., Lee, M. J., Balentine, D., Kuo, M. C., and Schantz, S. P. Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers. Cancer Epidemiol.Biomarkers Prev. 1998;7(4):351-354. View abstract. Yang, C. S., Lambert, J. D., and Sang, S. Antioxidative and anti-carcinogenic activities of tea polyphenols. Arch.Toxicol. 2009;83(1):11-21. View abstract. Yang, H. Y., Yang, S. C., Chao, J. C., and Chen, J. R. Beneficial effects of catechin-rich green tea and inulin on the body composition of overweight adults. Br.J.Nutr. 2012;107(5):749-754. View abstract. Yang, T. T. and Koo, M. W. Hypocholesterolemic effects of Chinese tea. Pharmacol Res 1997;35(6):505-512. View abstract. Yellapu, R. K., Mittal, V., Grewal, P., Fiel, M., and Schiano, T. Acute liver failure caused by 'fat burners' and dietary supplements: a case report and literature review. Can.J.Gastroenterol. 2011;25(3):157-160. View abstract. Yian LG. Case study on the effectiveness of green tea bags as a secondary dressing to control malodour of fungating breast cancer wounds. Singapore Nurs J 2005;32:42-48. Yoon, J. Y., Kwon, H. H., Min, S. U., Thiboutot, D. M., and Suh, D. H. Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes. J.Invest Dermatol. 2013;133(2):429-440. View abstract. Yoto, A., Motoki, M., Murao, S., and Yokogoshi, H. Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses. J.Physiol Anthropol. 2012;31:28. View abstract. Yu, G. P., Hsieh, C. C., Wang, L. Y., Yu, S. Z., Li, X. L., and Jin, T. H. Green-tea consumption and risk of stomach cancer: a population-based case-control study in Shanghai, China. Cancer Causes Control 1995;6(6):532-538. View abstract. Yuan, Y. B., Wang, Z. Q., Hu, X. X., and Jiang, Q. W. Cohort study of drinking green tea on liver disease (in Chinese). Pract Prev Med 2005;12:1016-1018. Zhang, M., Holman, C. D., Huang, J. P., and Xie, X. Green tea and the prevention of breast cancer: a case-control study in Southeast China. Carcinogenesis 2007;28(5):1074-1078. View abstract. Zhang, M., Huang, J., Xie, X., and Holman, C. D. Dietary intakes of mushrooms and green tea combine to reduce the risk of breast cancer in Chinese women. Int J Cancer 3-15-2009;124(6):1404-1408. View abstract. Zhang, W., Lopez-Garcia, E., Li, T. Y., Hu, F. B., and van Dam, R. M. Coffee consumption and risk of cardiovascular diseases and all-cause mortality among men with type 2 diabetes. Diabetes Care 2009;32(6):1043-1045. View abstract. Zhang, Z. M., Yang, X. Y., Yuan, J. H., Sun, Z. Y., and Li, Y. Q. Modulation of NRF2 and UGT1A expression by epigallocatechin-3-gallate in colon cancer cells and BALB/c mice. Chin Med J (Engl.) 7-20-2009;122(14):1660-1665. View abstract. Zhang, Z. Q., Lui, Q. F., Huang, Y. R., and Wu, Y. D. An epidemiological trial of using green tea to prevent liver cancer (in Chinese). GuangXi Prev Med 1995;1:5-7. Zheng, J., Yang, B., Huang, T., Yu, Y., Yang, J., and Li, D. Green tea and black tea consumption and prostate cancer risk: an exploratory meta-analysis of observational studies. Nutr.Cancer 2011;63(5):663-672. View abstract. Zhou, Y., Li, N., Zhuang, W., Liu, G., Wu, T., Yao, X., Du, L., Wei, M., and Wu, X. Green tea and gastric cancer risk: meta-analysis of epidemiologic studies. Asia Pac.J Clin Nutr. 2008;17(1):159-165. View abstract. Abdelkawy KS, Abdelaziz RM, Abdelmageed AM, Donia AM, El-Khodary NM. Effects of green tea extract on atorvastatin pharmacokinetics in healthy volunteers. Eur J Drug Metab Pharmacokinet. 2020;45(3):351-360. View abstract. Abe O, Ono T, Sato H, et al. Role of (-)-epigallocatechin gallate in the pharmacokinetic interaction between nadolol and green tea in healthy volunteers. Eur J Clin Pharmacol 2018;74(6):775-83. doi: 10.1007/s00228-018-2436-2. View abstract. Abe SK, Saito E, Sawada N, et al. Green tea consumption and mortality in Japanese men and women: a pooled analysis of eight population-based cohort studies in Japan. Eur J Epidemiol. 2019 Oct;34(10):917-926. View abstract. Acheson KJ, Gremaud G, Meirim I, et al. Metabolic effects of caffeine in humans: lipid oxidation or futile cycling? Am J Clin Nutr 2004;79:40-6. View abstract. Adcocks C, Collin P, Buttle DJ. Catechins from green tea (Camellia sinensis) inhibit bovine and human cartilage proteoglycan and type II collagen degradation in vitro. J Nutr 2002;132:341-6. View abstract. Ahmed S, Rahman A, Hasnain A, et al. Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes. Free Radic Biol Med 2002;33:1097-105. View abstract. Ahn WS, Yoo J, Huh SW, et al. Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions. Eur J Cancer Prev 2003;12:383-90. View abstract. Al-Momen H, Hussein HK, Al-Attar Z, Hussein MJ. Green tea influence on iron overload in thalassemia intermedia patients: a randomized controlled trial. F1000Res. 2020;9:1136. View abstract. Ali M, Afzal M. A potent inhibitor of thrombin stimulated platelet thromboxane formation from unprocessed tea. Prostaglandins Leukot Med 1987;27:9-13. View abstract. American Academy of Pediatrics. The transfer of drugs and other chemicals into human milk. Pediatrics 2001;108:776-89. View abstract. Annaba F, Kumar P, Dudeja AK, et al. Green tea catechin EGCG inhibits ileal apical sodium bile acid transporter ASBT. Am.J Physiol Gastrointest.Liver Physiol 2010;298:G467-G473. View abstract. Aqel RA, Zoghbi GJ, Trimm JR, et al. Effect of caffeine administered intravenously on intracoronary-administered adenosine-induced coronary hemodynamics in patients with coronary artery disease. Am J Cardiol 2004;93:343-6. View abstract. Ardlie NG, Glew G, Schultz BG, Schwartz CJ. Inhibition and reversal of platelet aggregation by methyl xanthines. Thromb Diath Haemorrh 1967;18:670-3. View abstract. Armidin RP, Yanti GN. Effectiveness of rinsing black tea compared to green tea in decreasing Streptococcus mutans. Open Access Maced J Med Sci. 2019;7(22):3799-3802. View abstract. Asbaghi O, Fouladvand F, Gonzalez MJ, Aghamohammadi V, Choghakhori R, Abbasnezhad A. Effect of green tea on anthropometric indices and body composition in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Complement Med Res. 2020:1-8. View abstract. Asbaghi O, Fouladvand F, Gonzalez MJ, Ashtary-Larky D, Choghakhori R, Abbasnezhad A. Effect of green tea on glycemic control in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Diabetes Metab Syndr. 2020;15(1):23-31. View abstract. Asbaghi O, Fouladvand F, Moradi S, Ashtary-Larky D, Choghakhori R, Abbasnezhad A. Effect of green tea extract on lipid profile in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Diabetes Metab Syndr. 2020;14(4):293-301. View abstract. Ascherio A, Zhang SM, Hernan MA, et al. Prospective study of caffeine intake and risk of Parkinson's disease in men and women. Proceedings 125th Ann Mtg Am Neurological Assn. Boston, MA: 2000;Oct 15-18:42 (abstract 53). Avisar R, Avisar E, Weinberger D. Effect of coffee consumption on intraocular pressure. Ann Pharmacother 2002;36:992-5.. View abstract. Baba Y, Inagaki S, Nakagawa S, Kaneko T, Kobayashi M, Takihara T. Effect of daily intake of green tea catechins on cognitive function in middle-aged and older subjects: A randomized, placebo-controlled study. Molecules. 2020;25(18):4265. View abstract. Baba Y, Inagaki S, Nakagawa S, Kobayashi M, Kaneko T, Takihara T. Effects of daily matcha and caffeine intake on mild acute psychological stress-related cognitive function in middle-aged and older adults: A randomized placebo-controlled study. Nutrients 2021;13(5):1700. View abstract. Beach CA, Mays DC, Guiler RC, et al. Inhibition of elimination of caffeine by disulfiram in normal subjects and recovering alcoholics. Clin Pharmacol Ther 1986;39:265-70. View abstract. Bell DG, Jacobs I, Ellerington K. Effect of caffeine and ephedrine ingestion on anaerobic exercise performance. Med Sci Sports Exerc 2001;33:1399-403. View abstract. Benowitz NL, Osterloh J, Goldschlager N, et al. Massive catecholamine release from caffeine poisoning. JAMA 1982;248:1097-8. View abstract. Bettuzzi S, Brausi M, Rizzi F, et al. Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study. Cancer Res 2006;66:1234-40. View abstract. Bonkovsky HL. Hepatotoxicity associated with supplements containing Chinese green tea (Camellia sinensis). Ann Intern Med 2006;144:68-71. View abstract. Booth SL, Madabushi HT, Davidson KW, et al. Tea and coffee brews are not dietary sources of vitamin K-1 (phylloquinone). J Am Diet Assoc 1995;95:82-3. View abstract. Bracken MB, Triche EW, Belanger K, et al. Association of maternal caffeine consumption with decrements in fetal growth. Am J Epidemiol 2003;157:456-66.. View abstract.

Bradley Pharmaceuticals. Veregen Prescribing Information. October 2006.

Briggs GB, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 1998. Brown NJ, Ryder D, Branch RA. A pharmacodynamic interaction between caffeine and phenylpropanolamine. Clin Pharmacol Ther 1991;50:363-71. View abstract. Bushman JL. Green tea and cancer in humans: a review of the literature. Nutr Cancer 1998;31:151-9. View abstract. Caldeira D, Martins C, Alves LB, Pereira H, Ferreira JJ, Costa J. Caffeine does not increase the risk of atrial fibrillation: a systematic review and meta-analysis of observational studies. Heart. 2013;99(19):1383-9. doi: 10.1136/heartjnl-2013-303950. Review. View abstract. Cannon ME, Cooke CT, McCarthy JS. Caffeine-induced cardiac arrhythmia: an unrecognised danger of healthfood products. Med J Aust 2001;174:520-1. View abstract. Cao Y, Cao R. Angiogenesis inhibited by drinking tea. Nature 1999;398:381. View abstract. Chen, Y., Xiao, C. Q., He, Y. J., Chen, B. L., Wang, G., Zhou, G., Zhang, W., Tan, Z. R., Cao, S., Wang, L. P., and Zhou, H. H. Genistein alters caffeine exposure in healthy female volunteers. Eur.J Clin.Pharmacol. 2011;67(4):347-353. View abstract. Cheng M, Hu Z, Lu X, Huang J, Gu D. Caffeine intake and atrial fibrillation incidence: dose response meta-analysis of prospective cohort studies. Can J Cardiol. 2014 Apr;30(4):448-54. doi: 10.1016/j.cjca.2013.12.026. Epub 2014 2. Review. View abstract. Chien CF, Wu YT, Lee WC, et al. Herb-drug interaction of Andrographis paniculata extract and andrographolide on the pharmacokinetics of theophylline in rats. Chem Biol Interact 2010;184:458-65. View abstract. Chiu KM. Efficacy of calcium supplements on bone mass in postmenopausal women. J Gerontol A Biol Sci Med Sci 1999;54:M275-80. View abstract. Choi JH, Chai YM, Joo GJ, et al. Effects of green tea catechin on polymorphonuclear leukocyte 5'-lipoxygenase activity, leukotriene B4 synthesis, and renal damage in diabetic rats. Ann Nutr Metab 2004;48:151-5. View abstract. Choi JS, Burm JP. Effects of oral epigallocatechin gallate on the pharmacokinetics of nicardipine in rats. Arch Pharm Res. 2009 Dec;32(12):1721-5. View abstract. Choi YT, Jung CH, Lee SR, et al. The green tea polyphenol (-)-epigallocatechin gallate attenuates beta-amyloid-induced neurotoxicity in cultured hippocampal neurons. Life Sci 2001;70:603-14.. View abstract. Chong PW, Beah ZM, Grube B, Riede L. IQP-GC-101 reduces body weight and body fat mass: a randomized, double-blind, placebo-controlled study. Phytother Res. 2014 Oct;28(10):1520-6. View abstract. Chong SJ, Howard KA, Knox C. Hypokalaemia and drinking green tea: a literature review and report of 2 cases. BMJ Case Rep. 2016;2016. pii: bcr2016214425. View abstract. Chou T. Wake up and smell the coffee. Caffeine, coffee, and the medical consequences. West J Med 1992;157:544-53. View abstract. Chroscinska-Krawczyk, M., Jargiello-Baszak, M., Walek, M., Tylus, B., and Czuczwar, S. J. Caffeine and the anticonvulsant potency of antiepileptic drugs: experimental and clinical data. Pharmacol.Rep. 2011;63(1):12-18. View abstract. Chu KO, Wang CC, Chu CY, et al. Pharmacokinetic studies of green tea catechins in maternal plasma and fetuses in rats. J Pharm Sci 2006;95:1372-81. View abstract. Chung JH, Choi DH, Choi JS. Effects of oral epigallocatechin gallate on the oral pharmacokinetics of verapamil in rats. Biopharm Drug Dispos. 2009 Mar;30(2):90-3. View abstract Chung LY, Cheung TC, Kong SK, et al. Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells. Life Sci 2001;68:1207-14. View abstract. Chung M, Zhao N, Wang D, et al. Dose-response relation between tea consumption and risk of cardiovascular disease and all-cause mortality: A systematic review and meta-analysis of population-based studies. Adv Nutr. 2020;11(4):790-814. View abstract. Cone EH, Lange R, Darwin WD. In vivo adulteration: excess fluid ingestion causes false-negative marijuana and cocaine urine test results. J Anal Toxicol 1998;22:460-73. View abstract. Correa A, Stolley A, Liu Y. Prenatal tea consumption and risks of anencephaly and spina bifida. Ann Epidemiol 2000;10:476-7. View abstract. Crew KD, Brown P, Greenlee H, Bevers TB, Arun B, Hudis C, McArthur HL, Chang J, Rimawi M, Vornik L, Cornelison TL, Wang A, Hibshoosh H, Ahmed A, Terry MB, Santella RM, Lippman SM, Hershman DL. Phase IB randomized, double-blinded, placebo-controlled, dose escalation study of polyphenon E in women with hormone receptor-negative breast cancer. Cancer Prev Res (Phila). 2012 Sep;5(9):1144-54. View abstract. Cronin JR. Green tea extract stokes thermogenesis: will it replace ephedra? Altern Comp Ther 2000;6:296-300. Daniel, W. A., Syrek, M., Rylko, Z., and Kot, M. Effects of phenothiazine neuroleptics on the rate of caffeine demethylation and hydroxylation in the rat liver. Pol.J Pharmacol 2001;53(6):615-621. View abstract. Darweesh RS, El-Elimat T, Zayed A, et al. The effect of grape seed and green tea extracts on the pharmacokinetics of imatinib and its main metabolite, N-desmethyl imatinib, in rats. BMC Pharmacol Toxicol. 2020;21(1):77.View abstract. de Maat MP, Pijl H, Kluft C, Princen HM. Consumption of black and green tea had no effect on inflammation, haemostasis and endothelial markers in smoking healthy individuals. Eur J Clin Nutr 2000;54:757-63.. View abstract. Deshpande A, Deshpande N, Raol R, Patel K, Jaiswal V, Wadhwa M. Effect of green tea, ginger plus green tea, and chlorhexidine mouthwash on plaque-induced gingivitis: A randomized clinical trial. J Indian Soc Periodontol 2021;25(4):307-312. View abstract. Dews PB, Curtis GL, Hanford KJ, O'Brien CP. The frequency of caffeine withdrawal in a population-based survey and in a controlled, blinded pilot experiment. J Clin Pharmacol 1999;39:1221-32. View abstract. Dews PB, O'Brien CP, Bergman J. Caffeine: behavioral effects of withdrawal and related issues. Food Chem Toxicol 2002;40:1257-61. View abstract. Dixit S, Stein PK, Dewland TA, Dukes JW, Vittinghoff E, Heckbert SR, Marcus GM. Consumption of Caffeinated Products and Cardiac Ectopy. J Am Heart Assoc. 2016 26;5(1). pii: e002503. doi: 10.1161/JAHA.115.002503. View abstract. Donovan JL, Chavin KD, Devane CL, et al. Green tea (Camellia sinensis) extract does not alter cytochrome P450 3A4 or 2D6 activity in healthy volunteers. Drug Metab Dispos 2004;32:906-8. View abstract. Dostal AM, Arikawa A, Espejo L, Kurzer MS. Long-term supplementation of green tea extract does not modify adiposity or bone mineral density in a randomized trial of overweight and obese postmenopausal women. J Nutr. 2016;146(2):256-64. View abstract. Dostal AM, Samavat H, Bedell S, et al. The safety of green tea extract supplementation in postmenopausal women at risk for breast cancer: results of the Minnesota Green Tea Trial. Food Chem Toxicol. 2015 Sep;83:26-35. View abstract. Dreher HM. The effect of caffeine reduction on sleep quality and well-being in persons with HIV. J Psychosom Res 2003;54:191-8.. View abstract. Drug Record: Green Tea (Camellia Sinesis). LiverTox: National Institutes of Health, U.S. Department of Health & Human Services, March 2014. https://livertox.nlm.nih.gov//GreenTea.htm. Accessed November 20, 2017. Dryden GW, Lam A, Beatty K, Qazzaz HH, McClain CJ. A pilot study to evaluate the safety and efficacy of an oral dose of (-)-epigallocatechin-3-gallate-rich polyphenon E in patients with mild to moderate ulcerative colitis. Inflamm Bowel Dis. 2013 Aug;19(9):1904-12. View abstract. Dulloo AG, Duret C, Rohrer D, et al. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutr 1999;70:1040-5. View abstract. Durlach PJ. The effects of a low dose of caffeine on cognitive performance. Psychopharmacology (Berl) 1998;140:116-9. View abstract. Durrant KL. Known and hidden sources of caffeine in drug, food, and natural products. J Am Pharm Assoc 2002;42:625-37. View abstract. Egert S, Tereszczuk J, Wein S, et al. Simultaneous ingestion of dietary proteins reduces the bioavailability of galloylated catechins from green tea in humans. Eur J Nutr. 2013 Feb;52(1):281-8. View abstract. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182 Elmets CA, Singh D, Tubesing K, et al. Cutaneous photoprotection from ultraviolet injury by green tea polyphenols. J Am Acad Dermatol 2001;44:425-32. View abstract. Emami H, Nikoobin F, Roayaei M, Ziya HR. Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of green tea in preventing acute gastrointestinal complications due to radiotherapy. J Res Med Sci. 2014;19(5):445-50. View abstract. Eshghpour M, Mortazavi H, Mohammadzadeh Rezaei N, Nejat A. Effectiveness of green tea mouthwash in postoperative pain control following surgical removal of impacted third molars: double blind randomized clinical trial. Daru. 2013 Jul 18;21(1):59. View abstract.

Eskenazi B. Caffeine—filtering the facts. N Engl J Med 1999;341:1688-9. View abstract.

Essmat A, Hussein MS. Green tea extract for mild-to-moderate diabetic peripheral neuropathy A randomized controlled trial. Complement Ther Clin Pract 2021;43:101317. View abstract. Farabegoli F, Papi A, Bartolini G, Ostan R, Orlandi M. (-)-Epigallocatechin-3-gallate downregulates Pg-P and BCRP in a tamoxifen resistant MCF-7 cell line. Phytomedicine. 2010 Apr;17(5):356-62. View abstract. FDA. Letter updating the green tea and risk of breast cancer and prostate cancer health claim. April 2012. Available at: https://wayback.archive-it.org/7993/20171114183707/https://www.fda.gov/Food/IngredientsPackagingLabeling/LabelingNutrition/ucm301644.htm. Accessed January 28, 2019. FDA. Proposed rule: dietary supplements containing ephedrine alkaloids. Available at: www.verity.fda.gov (Accessed 25 January 2000). Fernandes O, Sabharwal M, Smiley T, et al. Moderate to heavy caffeine consumption during pregnancy and relationship to spontaneous abortion and abnormal fetal growth: a meta-analysis. Reprod Toxicol 1998;12:435-44. View abstract. Ferrini RL, Barrett-Connor E. Caffeine intake and endogenous sex steroid levels in postmenopausal women. The Rancho Bernardo Study. Am J Epidemiol 1996:144:642-4. View abstract. Filimonova AA, Ziganshina LE, Ziganshin AU, Chichirov AA. On the possibility of patient phenotyping on the basis of cytochrome p-450 1A2 isoenzyme activity using caffeine as the test substrate. Eksp Klin Farmakol 2009;72:61-5. View abstract. Filippini T, Malavolti M, Borrelli F, et al. Green tea (Camellia sinensis) for the prevention of cancer. Cochrane Database Syst Rev. 2020;3(3):CD005004. View abstract. Forrest WH Jr, Bellville JW, Brown BW Jr. The interaction of caffeine with pentobarbital as a nighttime hypnotic. Anesthesiology 1972;36:37-41. View abstract. Foster S, Duke JA. Eastern/Central Medicinal Plants. New York, NY: Houghton Mifflin Co., 1990. Fuhr, U., Strobl, G., Manaut, F., Anders, E. M., Sorgel, F., Lopez-de-Brinas, E., Chu, D. T., Pernet, A. G., Mahr, G., Sanz, F., and . Quinolone antibacterial agents: relationship between structure and in vitro inhibition of the human cytochrome P450 isoform CYP1A2. Mol.Pharmacol. 1993;43(2):191-199. View abstract. Gahreman D, Heydari M, Boutcher Y, Freund J, Boutcher S. The effect of green tea ingestion and interval sprinting exercise on the body composition of overweight males: A randomized trial. Nutrients. 2016;8(8). pii: E510. View abstract. Gallo E, Maggini V, Berardi M, Pugi A, Notaro R, Talini G, Vannozzi G, Bagnoli S, Forte P, Mugelli A, Annese V, Firenzuoli F, Vannacci A. Is green tea a potential trigger for autoimmune hepatitis? Phytomedicine. 2013 Oct 15;20(13):1186-9. View abstract. Gao M, Ma W, Chen XB, Chang ZW, Zhang XD, Zhang MZ. Meta-analysis of green tea drinking and the prevalence of gynecological tumors in women. Asia Pac J Public Health. 2013 Jul;25(4 Suppl):43S-8S. View abstract Garbisa S, Biggin S, Cavallarin N, et al. Tumor invasion: molecular shears blunted by green tea. Nat Med 1999;5:1216. View abstract. Garcia FA, Cornelison T, Nuño T, Greenspan DL, Byron JW, Hsu CH, Alberts DS, Chow HH. Results of a phase II randomized, double-blind, placebo-controlled trial of Polyphenon E in women with persistent high-risk HPV infection and low-grade cervical intraepithelial neoplasia. Gynecol Oncol. 2014 Feb;132(2):377-82. View abstract. Gasior, M., Borowicz, K., Buszewicz, G., Kleinrok, Z., and Czuczwar, S. J. Anticonvulsant activity of phenobarbital and valproate against maximal electroshock in mice during chronic treatment with caffeine and caffeine discontinuation. Epilepsia 1996;37(3):262-268. View abstract. Gasior, M., Swiader, M., Przybylko, M., Borowicz, K., Turski, W. A., Kleinrok, Z., and Czuczwar, S. J. Felbamate demonstrates low propensity for interaction with methylxanthines and Ca2+ channel modulators against experimental seizures in mice. Eur.J Pharmacol 7-10-1998;352(2-3):207-214. View abstract. Geleijnse JM, Launer LJ, van der Kuip DA, et al. Inverse association of tea and flavonoid intakes with incident myocardial infarction: the Rotterdam Study. Am J Clin Nutr 2002;75:880-6. View abstract. Gianfredi V, Nucci D, Abalsamo A, et al. Green Tea Consumption and Risk of Breast Cancer and Recurrence-A Systematic Review and Meta-Analysis of Observational Studies. Nutrients. 2018;10(12). pii: E1886. View abstract. Gloro R, Hourmand-Ollivier I, Mosquet B, et al. Fulminant hepatitis during self-medication with hydroalcoholic extract of green tea. Eur J Gastroenterol Hepatol 2005;17:1135-7. View abstract. Goh BC, Reddy NJ, Dandamudi UB, et al. An evaluation of the drug interaction potential of pazopanib, an oral vascular endothelial growth factor receptor tyrosine kinase inhibitor, using a modified Cooperstown 5+1 cocktail in patients with advanced solid tumors. Clin Pharmacol Ther 2010;88:652-9. View abstract. Golden ED, Lam PY, Kardosh A, et al. Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid-based proteasome inhibitors. Blood 2009;113:5927-37. View abstract. Gorski, J. C., Huang, S. M., Pinto, A., Hamman, M. A., Hilligoss, J. K., Zaheer, N. A., Desai, M., Miller, M., and Hall, S. D. The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivo. Clin Pharmacol Ther. 2004;75(1):89-100. View abstract. Graham HN. Green tea composition, consumption, and polyphenol chemistry. Prev Med 1992;21:334-50. View abstract. Grandjean AC, Reimers KJ, Bannick KE, Haven MC. The effect of caffeinated, non-caffeinated, caloric and non-caloric beverages on hydration. J Am Coll Nutr 2000;19:591-600.. View abstract. Green Tea Extract-Containing Natural Health Products - Rare Risk of Serious Liver Injury. Recalls & alerts. November 15, 2017. https://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2017/65100a-eng.php. Accessed November 10, 2017. Guo Y, Zhi F, Chen P, et al. Green tea and the risk of prostate cancer: A systematic review and meta-analysis. Medicine (Baltimore). 2017;96(13):e6426. View abstract. Gupta S, Saha B, Giri AK. Comparative antimutagenic and anticlastogenic effects of green tea and black tea: a review. Mutat Res 2002;512:37-65. View abstract. Hagg S, Spigset O, Mjorndal T, Dahlqvist R. Effect of caffeine on clozapine pharmacokinetics in healthy volunteers. Br J Clin Pharmacol 2000;49:59-63. View abstract. Haghighatdoost F, Hariri M. The effect of green tea on inflammatory mediators: A systematic review and meta-analysis of randomized clinical trials. Phytother Res. 2019 Sep;33(9):2274-2287. View abstract. Haller CA, Benowitz NL, Jacob P 3rd. Hemodynamic effects of ephedra-free weight-loss supplements in humans. Am J Med 2005;118:998-1003.. View abstract. Haller CA, Benowitz NL. Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. N Engl J Med 2000;343:1833-8. View abstract. Haller CA, Jacob P 3rd, Benowitz NL. Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use. Clin Pharmacol Ther 2002;71:421-32. View abstract. Haqqi TM, Anthony DD, Gupta S, et al. Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea. Proc Natl Acad Sci U S A 1999;96:4524-9. View abstract. Harder S, Fuhr U, Staib AH, Wolff T. Ciprofloxacin-caffeine: a drug interaction established using in vivo and in vitro investigations. Am J Med 1989;87:89S-91S. View abstract. Hartley L, Flowers N, Holmes J, Clarke A, Stranges S, Hooper L, Rees K. Green and black tea for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2013 Jun 18;6:CD009934. View abstract. Hartter, S., Nordmark, A., Rose, D. M., Bertilsson, L., Tybring, G., and Laine, K. Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity. Br.J.Clin.Pharmacol. 2003;56(6):679-682. View abstract.

Health Canada. Health Product Info Watch. October 2016; 5-6. Available at: https://www.hc-sc.gc.ca/dhp-mps/medeff/bulletin/hpiw-ivps_2016-10-eng.php#a15.

Healy DP, Polk RE, Kanawati L, et al. Interaction between oral ciprofloxacin and caffeine in normal volunteers. Antimicrob Agents Chemother 1989;33:474-8. View abstract. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. View abstract. Henning M, Fajardo-Lira C, Lee HW, et al. Catechin content of 18 teas and a green tea extract supplement correlates with the antioxidant capacity. Nutr Cancer 2003;45:226-35. View abstract. Hertog MGL, Sweetnam PM, Fehily AM, et al. Antioxidant flavonols and ischemic heart disease in a Welsh population of men: the Caerphilly Study. Am J Clin Nutr 1997;65:1489-94. View abstract. Heseltine D, Dakkak M, woodhouse K, et al. The effect of caffeine on postprandial hypotension in the elderly. J Am Geriatr Soc 1991;39:160-4. View abstract. Hill, A. M., Coates, A. M., Buckley, J. D., Ross, R., Thielecke, F., and Howe, P. R. Can EGCG reduce abdominal fat in obese subjects? J Am Coll Nutr 2007;26(4):396S-402S. View abstract. Hindmarch I, Quinlan PT, Moore KL, Parkin C. The effects of black tea and other beverages on aspects of cognition and psychomotor performance. Psychopharmacol 1998;139:230-8. View abstract. Ho CK, Choi SW, Siu PM, Benzie IF. Effects of single dose and regular intake of green tea (Camellia sinensis) on DNA damage, DNA repair, and heme oxygenase-1 expression in a randomized controlled human supplementation study. Mol Nutr Food Res. 2014 Jun;58(6):1379-83. View abstract. Hodgson JM, Croft KD, Mori TA, et al. Regular ingestion of tea does not inhibit in vivo lipid peroxidation in humans. J Nutr 2002;132:55-8.. View abstract. Hodgson JM, Puddey IB, Burke V, et al. Effects on blood pressure of drinking green and black tea. J Hypertens 1999;17:457-63. View abstract. Hodgson JM, Puddey IB, Croft KD, et al. Acute effects of ingestion of black and green tea on lipoprotein oxidation. Am J Clin Nutr 2000;71:1103-7. View abstract. Holmgren P, Norden-Pettersson L, Ahlner J. Caffeine fatalities--four case reports. Forensic Sci Int 2004;139:71-3. View abstract. Horner NK, Lampe JW. Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness. J Am Diet Assoc 2000;100:1368-80. View abstract. Howell LL, Coffin VL, Spealman RD. Behavioral and physiological effects of xanthines in nonhuman primates. Psychopharmacology (Berl) 1997;129:1-14. Vie

webmd.com - GREEN TEA: Overview, Uses, Side Effects, Precautions ... - WebMD

What are the five needs of a man?

Those five needs are admiration, physical attractiveness, recreational companionship, sexual fulfillment and domestic support. Nov 23, 2010

Last updated May 6, 2018

Is Coffee good for high blood pressure?

Increased coffee consumption is associated with a small decrease in hypertension, according to a 2017 review . The researchers found a 9% reduced...

Last updated May 23, 2019

Promotion

How long can you have prostate cancer before it spreads?

It can take up to 15 years for the cancer to spread from the prostate to other parts of the body (metastasis), typically the bones. In many cases,...

Last updated Nov 8, 2018

Promotion

Can I eat eggs everyday?

For most healthy adults, it's safe to eat 1–2 eggs a day depending on how much other cholesterol is in your diet. If you already have high...

Last updated Mar 14, 2019