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Where does your back hurt with lymphoma?

Some people experience lower back pain that is unexplained. It is thought that this may be caused by expanding lymph nodes pressing on nerves. As lymphomas progress and cancerous lymphocytes spread beyond the lymphatic system, the body loses its ability to fight infection.

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Signs and Symptoms of lymphoma are similar to those of other diseases and afflictions. The most common symptom is a painless swelling in a lymph node (called lymphadenopathy). People often first go to the doctor because they think they have a cold or respiratory infection that will not go away. The neck or armpits are common places noticed first, but the swelling can occur in other parts of the body including the groin (that may cause swelling in the legs or ankles) or the abdomen (that can cause cramping and bloating). Some lymphoma patients notice no swelling at all while others may complain of night sweats, weight loss, chills, a lack of energy or itching. There is usually no pain involved, especially when the lymphoma is in the early stage of development. Most people who have nonspecific complaints such as these will not have lymphoma. However, it is important that any person who has symptoms that persist see a doctor to confirm that no lymphoma or serious illness are present. The doctor will perform a complete physical examination and look for swollen lymph nodes under the chin, in the neck and tonsil area, on the shoulders and elbows, armpits, and in the groin. The doctor will also examine other parts of the body to see whether there is swelling or fluid in your chest or abdomen that could be caused by swollen lymph nodes. You will be asked about pain and examined for any weakness or paralysis that could be an enlarged lymph node pressing against nerves or the spinal cord. Your abdomen will be examined to see whether any internal organs are enlarged, especially the spleen. If the doctor suspects lymphoma, he or she will likely order further tests including a biopsy, blood tests, x-rays and perhaps a bone marrow evaluation.

Symptom Alert Checklist

The symptoms of lymphoma are commonly seen in other, less serious illnesses, such as influenza or other viral infection. These symptoms are often overlooked, but in cases of less serious illnesses they would not last very long. With lymphoma, these symptoms persist over time and cannot be explained by an infection or another disease. The checklist below lists the most common symptoms of lymphoma. Because of the common nature of these symptoms and because lymphoma symptoms do not appear in all cases, diagnosis is often problematic. If you suspect that you, a family member, friend or loved one may have lymphoma, see your doctor or qualified medical professional as soon as possible. Early diagnosis makes an impact on treatment and outcome.

Initial Symptoms of Lymphoma

Painless swelling in the upper body lymph nodes, i.e., the neck, collarbone region, armpits or groin. (A swollen lymph node is normally NOT as painful as an infected lymph node, which is common and can be painful.) This checklist lists the most common symptoms of lymphoma:

Chills/temperature swings

Fevers (especially at night)

Unexplained weight loss

Loss of appetite

Unusual tiredness/lack of energy

Persistent coughing

Breathlessness

Persistent itch all over the body without an apparent cause or rash

General fatigue

Enlarged tonsils

Headache.

More advanced lymphoma may present with the following symptoms:

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What are the odds I have lymphoma?

Overall, the chance that a man will develop NHL in his lifetime is about 1 in 42; for a woman, the risk is about 1 in 52. But each person's risk can be affected by a number of risk factors. NHL can occur at any age.

Key Statistics for Non-Hodgkin Lymphoma

Non-Hodgkin lymphoma (NHL) is one of the most common cancers in the United States, accounting for about 4% of all cancers. The American Cancer Society’s estimates for non-Hodgkin lymphoma in 2022 are: About 80,470 people (44,120 males and 36,350 females) will be diagnosed with NHL. This includes both adults and children.

About 20,250 people will die from this cancer (11,700males and 8,550 females).

Overall, the chance that a man will develop NHL in his lifetime is about 1 in 42; for a woman, the risk is about 1 in 52. But each person’s risk can be affected by a number of risk factors. NHL can occur at any age. In fact, it is one of the more common cancers among children, teens, and young adults. Still, the risk of developing NHL increases throughout life, and more than half of patients are 65 or older at the time of diagnosis. The aging of the American population is likely to lead to an increase in NHL cases during the coming years.

Visit the American Cancer Society’s Cancer Statistics Center for more key statistics.

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