Where does bone cancer start first?

Overview. Bone cancer can begin in any bone in the body, but it most commonly affects the pelvis or the long bones in the arms and legs. Bone cancer is rare, making up less than 1 percent of all cancers. In fact, noncancerous bone tumors are much more common than cancerous ones.

mayoclinic.org - Bone cancer - Symptoms and causes - Mayo Clinic

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Overview

Bone cancer can begin in any bone in the body, but it most commonly affects the pelvis or the long bones in the arms and legs. Bone cancer is rare, making up less than 1 percent of all cancers. In fact, noncancerous bone tumors are much more common than cancerous ones. The term "bone cancer" doesn't include cancers that begin elsewhere in the body and spread (metastasize) to the bone. Instead, those cancers are named for where they began, such as breast cancer that has metastasized to the bone. Some types of bone cancer occur primarily in children, while others affect mostly adults. Surgical removal is the most common treatment, but chemotherapy and radiation therapy also may be utilized. The decision to use surgery, chemotherapy or radiation therapy is based on the type of bone cancer being treated.

Types

Symptoms

Signs and symptoms of bone cancer include:

Bone pain

Swelling and tenderness near the affected area

Weakened bone, leading to fracture

Fatigue

Unintended weight loss

When to see a doctor

Make an appointment with your doctor if you or your child develops bone pain that:

Comes and goes

Becomes worse at night

Isn't helped by over-the-counter pain relievers

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Causes

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The cause of most bone cancers is unknown. A small number of bone cancers have been linked to hereditary factors, while others are related to previous radiation exposure.

Types of bone cancer

Osteosarcoma Open pop-up dialog box Close Osteosarcoma Osteosarcoma Osteosarcoma, the most common type of bone cancer, often starts in the long bones — the legs or the arms — but it can occur in any bone. Bone cancers are broken down into separate types based on the type of cell where the cancer began. The most common types of bone cancer include: Osteosarcoma. Osteosarcoma is the most common form of bone cancer. In this tumor, the cancerous cells produce bone. This variety of bone cancer occurs most often in children and young adults, in the bones of the leg or arm. In rare circumstances, osteosarcomas can arise outside of bones (extraskeletal osteosarcomas). Osteosarcoma is the most common form of bone cancer. In this tumor, the cancerous cells produce bone. This variety of bone cancer occurs most often in children and young adults, in the bones of the leg or arm. In rare circumstances, osteosarcomas can arise outside of bones (extraskeletal osteosarcomas). Chondrosarcoma. Chondrosarcoma is the second most common form of bone cancer. In this tumor, the cancerous cells produce cartilage. Chondrosarcoma usually occurs in the pelvis, legs or arms in middle-aged and older adults. Chondrosarcoma is the second most common form of bone cancer. In this tumor, the cancerous cells produce cartilage. Chondrosarcoma usually occurs in the pelvis, legs or arms in middle-aged and older adults. Ewing sarcoma. Ewing sarcoma tumors most commonly arise in the pelvis, legs or arms of children and young adults.

Risk factors

It's not clear what causes bone cancer, but doctors have found certain factors are associated with an increased risk, including:

mayoclinic.org - Bone cancer - Symptoms and causes - Mayo Clinic

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