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What vitamins affect lab results?

“Biotin in blood or other samples taken from patients who are ingesting high levels of biotin in dietary supplements can cause clinically significant incorrect lab test results.” The FDA has seen an increase in the number of reported adverse events — including one death — related to biotin interference with lab tests.

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Many doctor’s appointments begin with the same question: what medications are you taking? Though going through the list might feel tedious, it’s important to share an up-to-date rundown every time to determine how these drugs may interact with each other — and even how they could impact important blood tests. Last fall, the Food & Drug Administration (FDA) issued a safety alert regarding the water-soluble vitamin B7, or biotin, frequently found in multivitamins and supplements. Daily biotin recommendations range from 5 to 35 micrograms, depending on one’s age, gender, and other factors including pregnancy. Biotin can also be ingested naturally through common foods such as sweet potatoes, mushrooms, eggs, and spinach. “Many dietary supplements promoted for hair, skin, and nail benefits contain biotin levels up to 650 times the recommended daily intake of biotin,” states the FDA. “Biotin in blood or other samples taken from patients who are ingesting high levels of biotin in dietary supplements can cause clinically significant incorrect lab test results.” The FDA has seen an increase in the number of reported adverse events — including one death — related to biotin interference with lab tests. Biotin in patient samples can cause falsely high or falsely low results, depending on the test, and the influence of biotin may not always be apparent to healthcare providers or laboratories. “Incorrect test results may lead to inappropriate patient management or misdiagnosis,” the FDA cautions. “For example, a falsely low result for troponin, a clinically important biomarker to aid in the diagnosis of heart attacks, may lead to a missed diagnosis and potentially serious clinical implications.” High levels of biotin can skew common tests used to diagnose conditions including pregnancy, cancer, thyroid disease, heart disease, anemia, and other hormonal-related conditions. Fortunately, often only a day without taking the supplement is required for accurate test results. Keep an up-to-date list of your current medications on file with your physician to have them available for other medical providers. Be sure to note if you are currently taking biotin, and consider bringing your labeled multivitamin to appointments to be sure its contents are recorded.

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What not to do before a blood test?

Avoiding specific foods and drinks such as cooked meats, herbal tea, or alcohol. Making sure not to overeat the day before a test. Not smoking. Avoiding specific behaviors such as strenuous exercise or sexual activity.

How do I prepare for a lab test?

A laboratory (lab) test is a procedure in which a health care provider takes a sample of your blood, urine, other body fluid, or body tissue to get information about your health. Lab tests are often used to help diagnose or screen for a specific disease or condition. Screening helps diagnose diseases before symptoms occur. Other tests are used to monitor a disease or see if treatment is effective. Lab tests may also be done to provide more general information about your organs and body systems.

For any type of lab test, you should prepare for it by:

Following all the instructions given to you by your health care provider

Telling your provider or lab professional if you didn't follow these instructions exactly. It's important to be honest. Even a minor change from the instructions can have a big effect on your results. For example, some medicines raise or lower blood sugar levels. Taking them too close to a blood sugar test could affect your results. Telling your provider about any medicines, vitamins, or supplements that you are taking Taking these steps can help ensure your results will be accurate and reliable.

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