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What happens if you take fish oil everyday?

When taken by mouth: Fish oil is likely safe for most people in doses of 3 grams or less daily. Taking more than 3 grams daily might increase the chance of bleeding. Fish oil side effects include heartburn, loose stools, and nosebleeds. Taking fish oil supplements with meals or freezing them can reduce these issues.

webmd.com - FISH OIL: Overview, Uses, Side Effects, Precautions ... - WebMD
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Anonymous. Fish oil and plasma fibrinogen. BMJ. 1988;297(6648):615-616.

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Bowden, R. G., Wilson, R. L., Gentile, M., Ounpraseuth, S., Moore, P., and Leutholtz, B. C. Effects of omega-3 fatty acid supplementation on vascular access thrombosis in polytetrafluorethylene grafts. J Ren Nutr 2007;17(2):126-131. View abstract. Braden, G. A., Knapp, H. R., Fitzgerald, D. J., and FitzGerald, G. A. Dietary fish oil accelerates the response to coronary thrombolysis with tissue-type plasminogen activator. Evidence for a modest platelet inhibitory effect in vivo. Circulation 1990;82(1):178-187. View abstract. Braga, M., Gianotti, L., Nespoli, L., Radaelli, G., and Di, Carlo, V. Nutritional approach in malnourished surgical patients: a prospective randomized study. Arch.Surg. 2002;137(2):174-180. View abstract. Braga, M., Gianotti, L., Radaelli, G., Vignali, A., Mari, G., Gentilini, O., and Di, Carlo, V. Perioperative immunonutrition in patients undergoing cancer surgery: results of a randomized double-blind phase 3 trial. Arch.Surg. 1999;134(4):428-433. View abstract. Braga, M., Gianotti, L., Vignali, A., and Carlo, V. D. Preoperative oral arginine and n-3 fatty acid supplementation improves the immunometabolic host response and outcome after colorectal resection for cancer. Surgery 2002;132(5):805-814. View abstract. Braga, M., Vignali, A., Gianotti, L., Cestari, A., Profili, M., and Di, Carlo, V. Benefits of early postoperative enteral feeding in cancer patients. Infusionsther.Transfusionsmed. 1995;22(5):280-284. View abstract. Brouwer, I. A., Heeringa, J., Geleijnse, J. M., Zock, P. L., and Witteman, J. C. Intake of very long-chain n-3 fatty acids from fish and incidence of atrial fibrillation. The Rotterdam Study. Am.Heart J. 2006;151(4):857-862. View abstract. Brouwer, I. A., Katan, M. B., and Zock, P. L. Effects of n-3 fatty acids on arrhythmic events and mortality in the SOFA implantable cardioverter defibrillator trial. Am J Clin Nutr 2006;84(6):1554-1555. View abstract. Brown, A. J. and Roberts, D. C. Fish and fish oil intake: effect on haematological variables related to cardiovascular disease. Thromb.Res 10-15-1991;64(2):169-178. View abstract. Browne, J. C., Scott, K. M., and Silvers, K. M. Fish consumption in pregnancy and omega-3 status after birth are not associated with postnatal depression. J.Affect.Disord. 2006;90(2-3):131-139. View abstract. Brude, I. R., Finstad, H. S., Seljeflot, I., Drevon, C. A., Solvoll, K., Sandstad, B., Hjermann, I., Arnesen, H., and Nenseter, M. S. Plasma homocysteine concentration related to diet, endothelial function and mononuclear cell gene expression among male hyperlipidaemic smokers. Eur.J.Clin.Invest 1999;29(2):100-108. View abstract. Buckley, J. D., Burgess, S., Murphy, K. J., and Howe, P. R. DHA-rich fish oil lowers heart rate during submaximal exercise in elite Australian Rules footballers. J Sci Med Sport 2009;12(4):503-507. View abstract. Bureyko, T., Hurdle, H., Metcalfe, J. B., Clandinin, M. T., and Mazurak, V. C. Reduced growth and integrin expression of prostate cells cultured with lycopene, vitamin E and fish oil in vitro. Br J Nutr 2009;101(7):990-997. View abstract. Burr, M. L. Fish and the cardiovascular system. Prog.Food Nutr Sci 1989;13(3-4):291-316. View abstract. Burr, M. L., Sweetham, P. M., and Fehily, A. M. Diet and reinfarction. Eur Heart J 1994;15(8):1152-1153. View abstract. Busnach, G., Stragliotto, E., Minetti, E., Perego, A., Brando, B., Broggi, M. L., and Civati, G. Effect of n-3 polyunsaturated fatty acids on cyclosporine pharmacokinetics in kidney graft recipients: a randomized placebo- controlled study. J Nephrol. 1998;11(2):87-93. View abstract. Buydens-Branch, Branchey, M., and Hibbeln, J. R. Low plasma levels of docosahexaenoic acid are associated with an increased relapse vulnerability in substance abusers. Am J Addict. 2009;18(1):73-80. View abstract. Cabre, E., Manosa, M., and Gassull, M. A. Omega-3 fatty acids and inflammatory bowel diseases - a systematic review. Br.J.Nutr. 2012;107 Suppl 2:S240-S252. View abstract. Calabrese, J. R., Rapport, D. J., and Shelton, M. D. Fish oils and bipolar disorder: a promising but untested treatment. Arch.Gen.Psychiatry 1999;56(5):413-414. View abstract. Caniato, R. N., Alvarenga, M. E., and Garcia-Alcaraz, M. A. Effect of omega-3 fatty acids on the lipid profile of patients taking clozapine. Aust N Z J Psychiatry 2006;40(8):691-697. View abstract. Carlson, S. E., Cooke, R. J., Werkman, S. H., and Tolley, E. A. First year growth of preterm infants fed standard compared to marine oil n-3 supplemented formula. Lipids 1992;27(11):901-907. View abstract. Carlson, S. E., Rhodes, P. G., Rao, V. S., and Goldgar, D. E. Effect of fish oil supplementation on the n-3 fatty acid content of red blood cell membranes in preterm infants. Pediatr.Res 1987;21(5):507-510. View abstract. Carlson, S. E., Werkman, S. H., and Tolley, E. A. Effect of long-chain n-3 fatty acid supplementation on visual acuity and growth of preterm infants with and without bronchopulmonary dysplasia. Am.J Clin Nutr. 1996;63(5):687-697. View abstract. Carrero JJ, Lopez-Huertas E Salmeron LM Ramos VE Baro L Ros E. Simvastatin and supplementation with n-3 PUFAs and vitamins improves claudication distance in a randomized PILOT study in patients with peripheral vascular disease. Nutr Res 2006;26:637-643. Carrero, J. J., Fonolla, J., Marti, J. L., Jimenez, J., Boza, J. J., and Lopez-Huertas, E. Intake of fish oil, oleic acid, folic acid, and vitamins B-6 and E for 1 year decreases plasma C-reactive protein and reduces coronary heart disease risk factors in male patients in a cardiac rehabilitation program. J.Nutr. 2007;137(2):384-390. View abstract. Carrero, J. J., Lopez-Huertas, E., Salmeron, L. M., Baro, L., and Ros, E. Daily supplementation with (n-3) PUFAs, oleic acid, folic acid, and vitamins B-6 and E increases pain-free walking distance and improves risk factors in men with peripheral vascular disease. J.Nutr. 2005;135(6):1393-1399. View abstract. Carroll, K. K. Biological effects of fish oils in relation to chronic diseases. Lipids 1986;21(12):731-732. View abstract. Carter, V. M., Woolley, I., Jolley, D., Nyulasi, I., Mijch, A., and Dart, A. A randomised controlled trial of omega-3 fatty acid supplementation for the treatment of hypertriglyceridemia in HIV-infected males on highly active antiretroviral therapy. Sex Health 2006;3(4):287-290. View abstract. Castro, R., Queiros, J., Fonseca, I., Pimentel, J. P., Henriques, A. C., Sarmento, A. M., Guimaraes, S., and Pereira, M. C. Therapy of post-renal transplantation hyperlipidaemia: comparative study with simvastatin and fish oil. Nephrol Dial.Transplant. 1997;12(10):2140-2143. View abstract. Caughey, G. E., James, M. J., Proudman, S. M., and Cleland, L. G. Fish oil supplementation increases the cyclooxygenase inhibitory activity of paracetamol in rheumatoid arthritis patients. Complement Ther.Med. 2010;18(3-4):171-174. View abstract. Caygill, C. P. and Hill, M. J. Fish, n-3 fatty acids and human colorectal and breast cancer mortality. Eur J Cancer Prev 1995;4(4):329-332. View abstract. Cederholm, T. and Palmblad, J. Are omega-3 fatty acids options for prevention and treatment of cognitive decline and dementia? Curr Opin.Clin Nutr Metab Care 2010;13(2):150-155. View abstract. Cerchietti, L. C., Navigante, A. H., and Castro, M. A. Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and preferential Cox-2 inhibition on systemic syndromes in patients with advanced lung cancer. Nutr.Cancer 2007;59(1):14-20. View abstract. Chalon, S. Omega-3 fatty acids and monoamine neurotransmission. Prostaglandins Leukot.Essent.Fatty Acids 2006;75(4-5):259-269. View abstract. Chan, D. C., Watts, G. 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C., and Su, K. P. Omega-3 fatty acids are more beneficial in the depressive phase than in the manic phase in patients with bipolar I disorder. J.Clin.Psychiatry 2005;66(12):1613-1614. View abstract. Chiu, C. C., Huang, S. Y., Shen, W. W., and Su, K. P. Omega-3 fatty acids for depression in pregnancy. Am J Psychiatry 2003;160(2):385. View abstract. Chong, M. F., Lockyer, S., Saunders, C. J., and Lovegrove, J. A. Long chain n-3 PUFA-rich meal reduced postprandial measures of arterial stiffness. Clin.Nutr. 2010;29(5):678-681. View abstract. Christensen JH, Gustenhoff P, Ejlersen E, and et al. n-3 fatty acids and ventricular extrasystoles in patients with ventricular tachyarrhythmias. Nutr Res 1995;15(1):1-8. Christensen, J. H., Gustenhoff, P., Korup, E., Aaroe, J., Toft, E., Moller, J., Rasmussen, K., Dyerberg, J., and Schmidt, E. B. Effect of fish oil on heart rate variability in survivors of myocardial infarction: a double blind randomised controlled trial. BMJ 3-16-1996;312(7032):677-678. View abstract.

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Chua, B., Flood, V., Rochtchina, E., Wang, J. J., Smith, W., and Mitchell, P. Dietary fatty acids and the 5-year incidence of age-related maculopathy. Arch Ophthalmol 2006;124(7):981-986. View abstract. Clandinin, M. T., Van Aerde, J. E., Merkel, K. L., Harris, C. L., Springer, M. A., Hansen, J. W., and Diersen-Schade, D. A. Growth and development of preterm infants fed infant formulas containing docosahexaenoic acid and arachidonic acid. J Pediatr 2005;146(4):461-468. View abstract. Clayton, E. H., Hanstock, T. L., Hirneth, S. J., Kable, C. J., Garg, M. L., and Hazell, P. L. Reduced mania and depression in juvenile bipolar disorder associated with long-chain omega-3 polyunsaturated fatty acid supplementation. Eur.J.Clin.Nutr. 2009;63(8):1037-1040. View abstract. Cleland, L. G., Caughey, G. E., James, M. J., and Proudman, S. M. Reduction of cardiovascular risk factors with longterm fish oil treatment in early rheumatoid arthritis. J Rheumatol 2006;33(10):1973-1979. View abstract. Cleland, L. G., French, J. K., Betts, W. H., Murphy, G. A., and Elliott, M. J. Clinical and biochemical effects of dietary fish oil supplements in rheumatoid arthritis. J Rheumatol. 1988;15(10):1471-1475. View abstract. Cobiac, L., Clifton, P. M., Abbey, M., Belling, G. B., and Nestel, P. J. Lipid, lipoprotein, and hemostatic effects of fish vs fish-oil n-3 fatty acids in mildly hyperlipidemic males. Am J Clin Nutr 1991;53(5):1210-1216. View abstract. Cobiac, L., Nestel, P. J., Wing, L. M., and Howe, P. R. A low-sodium diet supplemented with fish oil lowers blood pressure in the elderly. J Hypertens. 1992;10(1):87-92. View abstract. Cobiac, L., Nestel, P. J., Wing, L. M., and Howe, P. R. Effects of dietary sodium restriction and fish oil supplements on blood pressure in the elderly. Clin Exp Pharmacol Physiol 1991;18(5):265-268. View abstract. Colangelo, L. A., He, K., Whooley, M. A., Daviglus, M. L., and Liu, K. Higher dietary intake of long-chain omega-3 polyunsaturated fatty acids is inversely associated with depressive symptoms in women. Nutrition 2009;25(10):1011-1019. View abstract. Colter, A. L., Cutler, C., and Meckling, K. A. Fatty acid status and behavioural symptoms of attention deficit hyperactivity disorder in adolescents: a case-control study. Nutr J 2008;7:8. View abstract. Conklin, S. M., Harris, J. I., Manuck, S. B., Yao, J. K., Hibbeln, J. R., and Muldoon, M. F. Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers. Psychiatry Res 7-30-2007;152(1):1-10. View abstract. Conklin, S. M., Manuck, S. B., Yao, J. K., Flory, J. D., Hibbeln, J. R., and Muldoon, M. F. High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism. Psychosom.Med. 2007;69(9):932-934. View abstract. Connor, W. E., Prince, M. J., Ullmann, D., Riddle, M., Hatcher, L., Smith, F. E., and Wilson, D. The hypotriglyceridemic effect of fish oil in adult-onset diabetes without adverse glucose control. Ann N Y Acad Sci 6-14-1993;683:337-340. View abstract. Conquer, J. A., Cheryk, L. A., Chan, E., Gentry, P. A., and Holub, B. J. Effect of supplementation with dietary seal oil on selected cardiovascular risk factors and hemostatic variables in healthy male subjects. Thromb.Res 11-1-1999;96(3):239-250. View abstract. Contacos, C., Barter, P. J., and Sullivan, D. R. Effect of pravastatin and omega-3 fatty acids on plasma lipids and lipoproteins in patients with combined hyperlipidemia. Arterioscler.Thromb. 1993;13(12):1755-1762. View abstract. Culp, B. R., Lands, W. E., Lucches, B. R., Pitt, B., and Romson, J. The effect of dietary supplementation of fish oil on experimental myocardial infarction. Prostaglandins 1980;20(6):1021-1031. View abstract. da Silva, T. M., Munhoz, R. P., Alvarez, C., Naliwaiko, K., Kiss, A., Andreatini, R., and Ferraz, A. C. Depression in Parkinson's disease: a double-blind, randomized, placebo-controlled pilot study of omega-3 fatty-acid supplementation. J.Affect.Disord. 2008;111(2-3):351-359. View abstract. Daly, J. M., Weintraub, F. N., Shou, J., Rosato, E. F., and Lucia, M. Enteral nutrition during multimodality therapy in upper gastrointestinal cancer patients. Ann.Surg. 1995;221(4):327-338. View abstract. Damsgaard, C. T., Frokiaer, H., Andersen, A. D., and Lauritzen, L. Fish oil in combination with high or low intakes of linoleic acid lowers plasma triacylglycerols but does not affect other cardiovascular risk markers in healthy men. J.Nutr. 2008;138(6):1061-1066. View abstract. Damsgaard, C. T., Lauritzen, L., Calder, P. C., Kjaer, T. R., and Frokiaer, H. Reduced ex vivo interleukin-6 production by dietary fish oil is not modified by linoleic acid intake in healthy men. J Nutr 2009;139(7):1410-1414. View abstract. Damsgaard, C. T., Schack-Nielsen, L., Michaelsen, K. F., Fruekilde, M. 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Fish oil and fenofibrate for the treatment of hypertriglyceridemia in HIV-infected subjects on antiretroviral therapy: results of ACTG A5186. J.Acquir.Immune.Defic.Syndr. 4-1-2008;47(4):459-466. View abstract. Gerber, M. Omega-3 fatty acids and cancers: a systematic update review of epidemiological studies. Br.J.Nutr. 2012;107 Suppl 2:S228-S239. View abstract. Geusens, P., Wouters, C., Nijs, J., Jiang, Y., and Dequeker, J. Long-term effect of omega-3 fatty acid supplementation in active rheumatoid arthritis. A 12-month, double-blind, controlled study. Arthritis Rheum. 1994;37(6):824-829. View abstract. Ghebremeskel, K., Burns, L., Costeloe, K., Burden, T. J., Harbige, L., Thomas, B., and Temple, E. Plasma vitamin A and E in preterm babies fed on breast milk or formula milk with or without long-chain polyunsaturated fatty acids. Int.J.Vitam.Nutr.Res. 1999;69(2):83-91. View abstract. Giacco, R., Cuomo, V., Vessby, B., Uusitupa, M., Hermansen, K., Meyer, B. 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Ginsberg, G. L. and Toal, B. F. Quantitative approach for incorporating methylmercury risks and omega-3 fatty acid benefits in developing species-specific fish consumption advice. Environ Health Perspect. 2009;117(2):267-275. View abstract. Glaum, M., Metzelthin, E., Junker, S., Luley, C., and Klor, H. U. [Comparative effect of oral fat loads with saturated, omega-6 and omega- 3 fatty acids before and after fish oil capsule therapy in healthy probands]. Klin.Wochenschr 1990;68 Suppl 22:103-105. View abstract. Gogos, C. A., Ginopoulos, P., Salsa, B., Apostolidou, E., Zoumbos, N. C., and Kalfarentzos, F. Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy: a randomized control trial. Cancer 1-15-1998;82(2):395-402. View abstract.

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Treatment for 2 mo with n 3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: a randomized controlled study. Am.J.Clin.Nutr. 2007;86(6):1670-1679. View abstract. Kairaluoma, L., Narhi, V., Ahonen, T., Westerholm, J., and Aro, M. Do fatty acids help in overcoming reading difficulties? A double-blind, placebo-controlled study of the effects of eicosapentaenoic acid and carnosine supplementation on children with dyslexia. Child Care Health Dev. 2009;35(1):112-119. View abstract. Kalmijn, S., Feskens, E. J., Launer, L. J., and Kromhout, D. Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men. Am J Epidemiol 1-1-1997;145(1):33-41. View abstract. Kalmijn, S., Launer, L. J., Ott, A., Witteman, J. C., Hofman, A., and Breteler, M. M. Dietary fat intake and the risk of incident dementia in the Rotterdam Study. Ann Neurol. 1997;42(5):776-782. View abstract. Kamphuis, M. H., Geerlings, M. I., Tijhuis, M. A., Kalmijn, S., Grobbee, D. E., and Kromhout, D. Depression and cardiovascular mortality: a role for n-3 fatty acids? Am.J.Clin.Nutr. 2006;84(6):1513-1517. View abstract. Kang, J. X. and Leaf, A. Antiarrhythmic effects of polyunsaturated fatty acids. Recent studies. Circulation 10-1-1996;94(7):1774-1780. View abstract. Kang, J. X. and Leaf, A. The cardiac antiarrhythmic effects of polyunsaturated fatty acid. Lipids 1996;31 Suppl:S41-S44. View abstract. Kasim-Karakas, S. E., Herrmann, R., and Almario, R. Effects of omega-3 fatty acids on intravascular lipolysis of very-low- density lipoproteins in humans. Metabolism 1995;44(9):1223-1230. View abstract. Katan, M. B., Deslypere, J. P., van Birgelen, A. P., Penders, M., and Zegwaard, M. Kinetics of the incorporation of dietary fatty acids into serum cholesteryl esters, erythrocyte membranes, and adipose tissue: an 18-month controlled study. J Lipid Res 1997;38(10):2012-2022. View abstract. Katz, D. P., Manner, T., Furst, P., and Askanazi, J. The use of an intravenous fish oil emulsion enriched with omega-3 fatty acids in patients with cystic fibrosis. Nutrition 1996;12(5):334-339. View abstract. Kaul, U., Sanghvi, S., Bahl, V. K., Dev, V., and Wasir, H. S. Fish oil supplements for prevention of restenosis after coronary angioplasty. Int.J.Cardiol. 1992;35(1):87-93. View abstract. Kaushik, S., Wang, J. J., Flood, V., Liew, G., Smith, W., and Mitchell, P. Frequency of fish consumption, retinal microvascular signs and vascular mortality. Microcirculation. 2008;15(1):27-36. View abstract. Keck, P. E., Jr., Mintz, J., McElroy, S. L., Freeman, M. P., Suppes, T., Frye, M. A., Altshuler, L. L., Kupka, R., Nolen, W. A., Leverich, G. S., Denicoff, K. D., Grunze, H., Duan, N., and Post, R. M. Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder. Biol.Psychiatry 11-1-2006;60(9):1020-1022. View abstract. Keen, C., Olin, A. C., Eriksson, S., Ekman, A., Lindblad, A., Basu, S., Beermann, C., and Strandvik, B. Supplementation with fatty acids influences the airway nitric oxide and inflammatory markers in patients with cystic fibrosis. J.Pediatr.Gastroenterol.Nutr. 2010;50(5):537-544. View abstract. Kelley, D. S., Siegel, D., Vemuri, M., and Mackey, B. E. Docosahexaenoic acid supplementation improves fasting and postprandial lipid profiles in hypertriglyceridemic men. Am J Clin Nutr 2007;86(2):324-333. View abstract. Kelley, D. S., Siegel, D., Vemuri, M., Chung, G. H., and Mackey, B. E. Docosahexaenoic acid supplementation decreases remnant-like particle-cholesterol and increases the (n-3) index in hypertriglyceridemic men. J Nutr 2008;138(1):30-35. View abstract. Kelley, V. E., Ferretti, A., Izui, S., and Strom, T. B. A fish oil diet rich in eicosapentaenoic acid reduces cyclooxygenase metabolites, and suppresses lupus in MRL-lpr mice. J Immunol 1985;134(3):1914-1919. View abstract. Kenler, A. S., Swails, W. S., Driscoll, D. F., DeMichele, S. J., Daley, B., Babineau, T. J., Peterson, M. B., and Bistrian, B. R. Early enteral feeding in postsurgical cancer patients. Fish oil structured lipid-based polymeric formula versus a standard polymeric formula. Ann.Surg. 1996;223(3):316-333. View abstract. Keogh, J. B., Grieger, J. A., Noakes, M., and Clifton, P. M. Flow-mediated dilatation is impaired by a high-saturated fat diet but not by a high-carbohydrate diet. Arterioscler.Thromb.Vasc.Biol. 2005;25(6):1274-1279. View abstract. Khandelwal, S., Demonty, I., Jeemon, P., Lakshmy, R., Mukherjee, R., Gupta, R., Snehi, U., Niveditha, D., Singh, Y., van der Knaap, H. C., Passi, S. J., Prabhakaran, D., and Reddy, K. S. Independent and interactive effects of plant sterols and fish oil n-3 long-chain polyunsaturated fatty acids on the plasma lipid profile of mildly hyperlipidaemic Indian adults. Br.J.Nutr. 2009;102(5):722-732. View abstract. Kiecolt-Glaser, J. K., Belury, M. A., Porter, K., Beversdorf, D. Q., Lemeshow, S., and Glaser, R. Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults. Psychosom Med 2007;69(3):217-224. View abstract. Kim, J., Lim, S. Y., Shin, A., Sung, M. K., Ro, J., Kang, H. S., Lee, K. S., Kim, S. W., and Lee, E. S. Fatty fish and fish omega-3 fatty acid intakes decrease the breast cancer risk: a case-control study. BMC.Cancer 2009;9:216. View abstract. Kim, Y. I. Can fish oil maintain Crohn's disease in remission? Nutr Rev. 1996;54(8):248-252. View abstract. Kinsella, J. E., Lokesh, B., and Stone, R. A. Dietary n-3 polyunsaturated fatty acids and amelioration of cardiovascular disease: possible mechanisms. Am J Clin Nutr 1990;52(1):1-28. View abstract. Kirby, A., Woodward, A., Jackson, S., Wang, Y., and Crawford, M. A. A double-blind, placebo-controll

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