Prostate Restored
Photo: Ron Lach
Saw palmetto is a supplement made from the fruit of the Serenoa repens tree. It's often used to treat enlarged prostate, improve urinary function, and enhance hair growth. Some also use the supplement to boost libido and fertility and reduce inflammation. Finally, saw palmetto is claimed to have anticancer effects.
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Read More »Other potential benefits Saw palmetto is touted as providing additional benefits — though most are unsupported by strong science. For instance, test-tube research shows that Permixon – a specific formulation of saw palmetto – may reduce markers of inflammation in prostate cells. However, it’s unclear whether other saw palmetto supplements have the same effect ( 19 , 20 ). Permixon may also protect libido and fertility in men. Conventional drug therapy for BPH and LUTS has been shown to negatively impact sexual function in men. A review of 12 randomized controlled studies — the gold standard in nutrition research — compared Permixon with conventional drug therapy as a treatment for BPH and LUTS. Though both produced negative side effects on male sexual function, the saw palmetto supplement led to smaller drops in libido and lower impotence compared to the conventional drug treatment ( 12 ). Still, it’s unclear whether Permixon has the same effect in healthy men or whether other saw palmetto formulations offer similar protective benefits. What’s more, additional studies list decreased libido as a potential side effect of taking saw palmetto supplements — so more research is needed to confirm this ( 21 ). Finally, test-tube research suggests that saw palmetto may help kill and slow the growth of certain cancer cells, including of the prostate. Although promising, not all studies agree, and more research is needed ( 22 , 23 , 24 ). Summary Saw palmetto may reduce inflammation and protect your body against the growth of cancer cells. However, more research is needed. Safety and side effects Though raw and dried saw palmetto berries have been eaten for centuries, their safety hasn’t been directly studied. That said, studies suggest that saw palmetto supplements are generally safe for most people. The most common side effects include diarrhea, headache, fatigue, decreased libido, nausea, vomiting, and vertigo. Yet, they tend to be mild and reversible ( 21 ). More serious side effects like liver damage, pancreatitis, bleeding in the brain, and death have been reported in isolated cases. However, it isn’t always clear whether saw palmetto was the cause ( 21 , 25 , 26 , 27 ). Two case studies further report that young girls experienced hot flashes when given saw palmetto supplements to treat hair loss or hirsutism — a condition causing unwanted male-pattern hair growth in women ( 28 , 29 ). Moreover, there is some concern that saw palmetto may be linked to birth defects and may prevent the normal development of male genitalia ( 1 ). Therefore, use is strongly discouraged in children, as well as pregnant or breastfeeding women. What’s more, a review of labels and internet marketing materials cautions people with prostate disorders or hormone-dependent cancers to consult their healthcare provider before taking this supplement ( 1 ). They also warn that saw palmetto may interact with other medications, though additional reviews found no evidence of this ( 1 , 21 ). Summary Saw palmetto is generally considered safe. Still, children, pregnant and breastfeeding women, as well as those with certain medical conditions may need to refrain from taking this supplement. Potentially effective dosages Saw palmetto can be taken in many forms. Little research exists on effective dosages when the saw palmetto berries are eaten whole or steeped to make a tea. When taken as a dried supplement or an oily liquid extraction, saw palmetto appears most effective in daily dosages of 160–320 mg ( 12 , 13 , 16 , 17 ). That said, most studies have been done exclusively in men, so it’s unclear whether the same dosages are appropriate for women ( 1 ). Always consult your healthcare provider before taking saw palmetto to ensure your safety and appropriate dosage. Summary Saw palmetto appears most effective when taken in daily doses of 160–320 mg. However, more studies — particularly in women — are needed.
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