What causes XXY male syndrome?

It occurs as a random error during cell division early in fetal development. As a result, some of the body's cells have the usual one X chromosome and one Y chromosome (46,XY), and other cells have an extra copy of the X chromosome (47,XXY).

medlineplus.gov - Klinefelter syndrome - Genetics - MedlinePlus

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Klinefelter syndrome is a chromosomal condition in boys and men that can affect physical and intellectual development. Most commonly, affected individuals are taller than average are unable to father biological children (infertile); however the signs and symptoms of Klinefelter syndrome vary among boys and men with this condition. In some cases, the features of the condition are so mild that the condition is not diagnosed until puberty or adulthood, and researchers believe that up to 75 percent of affected men and boys are never diagnosed. Boys and men with Klinefelter syndrome typically have small testes that produce a reduced amount of testosterone (primary testicular insufficiency). Testosterone is the hormone that directs male sexual development before birth and during puberty. Without treatment, the shortage of testosterone can lead to delayed or incomplete puberty, breast enlargement (gynecomastia), decreased muscle mass, decreased bone density, and a reduced amount of facial and body hair. As a result of the small testes and decreased hormone production, affected males are infertile but may benefit from assisted reproductive technologies. Some affected individuals also have differences in their genitalia, including undescended testes (cryptorchidism), the opening of the urethra on the underside of the penis (hypospadias), or an unusually small penis (micropenis). Other physical changes associated with Klinefelter syndrome are usually subtle. Older children and adults with the condition tend to be somewhat taller than their peers. Other differences can include abnormal fusion of certain bones in the forearm (radioulnar synostosis), curved pinky fingers (fifth finger clinodactyly ), and flat feet (pes planus ). Children with Klinefelter syndrome may have low muscle tone (hypotonia) and problems with coordination that may delay the development of motor skills, such as sitting, standing, and walking. Affected boys often have learning disabilities, resulting in mild delays in speech and language development and problems with reading. Boys and men with Klinefelter syndrome tend to have better receptive language skills (the ability to understand speech) than expressive language skills (vocabulary and the production of speech) and may have difficulty communicating and expressing themselves. Individuals with Klinefelter syndrome tend to have anxiety, depression, impaired social skills, behavioral problems such as emotional immaturity and impulsivity, attention-deficit/hyperactivity disorder (ADHD), and limited problem-solving skills (executive functioning). About 10 percent of boys and men with Klinefelter syndrome have autism spectrum disorder. Nearly half of all men with Klinefelter syndrome develop metabolic syndrome, which is a group of conditions that include type 2 diabetes, high blood pressure (hypertension), increased belly fat, high levels of fats (lipids) such as cholesterol and triglycerides in the blood. Compared with unaffected men, adults with Klinefelter syndrome also have an increased risk of developing involuntary trembling (tremors), breast cancer (if gynecomastia develops), thinning and weakening of the bones (osteoporosis), and autoimmune disorders such as systemic lupus erythematosus and rheumatoid arthritis. (Autoimmune disorders are a large group of conditions that occur when the immune system attacks the body's own tissues and organs.)

Do all men's prostate enlarge with age?

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What's the first thing a woman notice in a man?

Your Hair/Beard Your hair is the most noticeable thing to a woman and usually it helps them decide if they really like it or understand it! Sep 12,...

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What are the 8 social problems?

The term “social problem” is usually taken to refer to social conditions that disrupt or damage society—crime, racism, and the like.

oxfordbibliographies.com - Social Problems - Sociology - Oxford Bibliographies

Introduction

The term “social problem” is usually taken to refer to social conditions that disrupt or damage society—crime, racism, and the like. “Social Problems” is the title of an undergraduate course taught at many colleges; a typical course discusses what is known about a series of conditions considered social problems. In contrast, the sociology of social problems defines social problem differently and adopts a different analytic approach. This approach—sometimes called constructionist—defines social problem in terms of a process, rather than a type of condition. It focuses on how and why people come to understand that some conditions ought to be viewed as a social problem, that is, how they socially construct social problems. Typically, the social problems process begins with claimsmakers who make claims that some condition ought to be considered a problem, that this problem should be understood in particular ways, and that it needs to be addressed. Other people respond to those claims and rework them, so that the social problem is constructed and reconstructed by the media, the general public, policymakers, the social-problems workers who implement policy, and critics that assess the policy’s effectiveness. The process is complex: some claims produce a speedy reaction, while others have difficulty finding an audience. The constructionist approach began to guide researchers in the 1970s and has generated a substantial literature that continues to develop in new directions.

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How do you identify a healthy person?

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