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What causes loss of testosterone?

Acquired circumstances that can lead to secondary hypogonadism include: Normal aging: Aging affects production and response to hormones. Obesity: High body fat can affect hormone production and response. Medications: Opioid pain meds and steroids can affect function of the pituitary gland and hypothalamus.

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Low testosterone prevalence Low testosterone (low T) affects 4 to 5 million men in the US. Testosterone is an important hormone in the human body. But it starts to decrease each year after age 30 . In some men this can be substantial. Between 19 and 39 percent of older men may have low levels of testosterone. Older men with low T have increasingly sought testosterone replacement therapy (TRT) in recent years. TRT addresses symptoms such as low libido, poor muscle mass, and low energy. It’s not just older men that are affected by low T. Young men, even babies and children, can also have this problem. Symptoms of low T Low levels of testosterone that are atypical of normal aging are due to other primary or secondary causes of hypogonadism. Hypogonadism in males happens when the testicles don’t produce enough testosterone. Hypogonadism can start during fetal development, during puberty, or during adulthood. Fetal development If hypogonadism begins during fetal development, the primary result is impaired growth of external sex organs. Depending on when hypogonadism starts and the level of testosterone present during fetal development, a male child can develop: female genitals

ambiguous genitals, neither clearly male or female

underdeveloped male genitals Puberty Normal growth can be jeopardized if hypogonadism occurs during puberty. Problems occur with: muscle development

deepening of the voice

lack of body hair

underdeveloped genitals

overly long limbs

low muscle mass

infertility

erectile dysfunction

decreased sex drive

slow hair growth or hair loss

loss of bone mass

gynecomastia Fatigue and mental fogginess are some commonly reported mental and emotional symptoms in men with low T. 9 Warning signs of low testosterone » Causes of low testosterone The two basic types of hypogonadism are primary and secondary hypogonadism. Primary hypogonadism Underactive testes cause primary hypogonadism. That’s because they don’t manufacture sufficient levels of testosterone for optimal growth and health. This underactivity can be caused by an inherited trait. It can also be acquired by accident or illness. Inherited conditions include: Undescended testicles : When the testicles fail to descend from the abdomen before birth : When the testicles fail to descend from the abdomen before birth Klinefelter’s syndrome : A condition in which a man is born with three sex chromosomes: X, X, and Y. : A condition in which a man is born with three sex chromosomes: X, X, and Y. Hemochromatosis: Too much iron in the blood causes testicular failure or pituitary damage Types of testicle damage that can lead to primary hypogonadism include: Physical injury to the testicles : Injury must occur to both testicles to affect testosterone levels. : Injury must occur to both testicles to affect testosterone levels. Mumps orchitis : A mumps infection can injure testicles.

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: A mumps infection can injure testicles. Cancer treatment: Chemotherapy or radiation can damage testicles. Secondary hypogonadism Secondary hypogonadism is caused by damage to the pituitary gland or hypothalamus. These parts of the brain control hormone production by the testes. Inherited or disease conditions in this category include: Pituitary disorders caused by drugs, kidney failure, or small tumors caused by drugs, kidney failure, or small tumors Kallmann syndrome , a condition connected to abnormal hypothalamus function , a condition connected to abnormal hypothalamus function Inflammatory diseases , such as tuberculosis, sarcoidosis, and histiocytosis, which can impact the pituitary gland and the hypothalamus , such as tuberculosis, sarcoidosis, and histiocytosis, which can impact the pituitary gland and the hypothalamus HIV/AIDS, which can affect the pituitary gland, hypothalamus, and testes Acquired circumstances that can lead to secondary hypogonadism include: Normal aging : Aging affects production and response to hormones. : Aging affects production and response to hormones. Obesity : High body fat can affect hormone production and response. : High body fat can affect hormone production and response. Medications : Opioid pain meds and steroids can affect function of the pituitary gland and hypothalamus. : Opioid pain meds and steroids can affect function of the pituitary gland and hypothalamus. Concurrent illness: Severe emotional stress or physical stress from an illness or surgery can cause the reproductive system to temporarily shut down. You may be affected by primary, secondary, or a mixed hypogonadism. Mixed hypogonadism is more common with increased age. People undergoing glucocorticoid therapy can develop the condition. It also can affect people with sickle-cell disease, thalassemia, or alcoholism. Learn more: 5 Natural testosterone boosters » Changes you can make If you’re experiencing symptoms of low T, lifestyle changes may help to ease your symptoms. A good first step is increasing activity levels and maintaining a healthy diet in order to reduce body fat. It can also be helpful to avoid glucocorticoid medications such as prednisone as well as opioid pain medications. Diet right: 8 Testosterone boosting foods »

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