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What causes death from prostate cancer?

Death from prostate cancer most often happens when cancer has spread (metastasized) to other organs in the body. This is known as the advanced stage of prostate cancer. The chances of survival decrease as cancer spreads beyond the prostate.

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Prostate cancer is cancer of the prostate gland in men. Death from prostate cancer most often happens when cancer has spread (metastasized) to other organs in the body. Prostate cancer is the most common cancer after skin cancer in men in the US and the second leading cause of cancer death. Prostate-specific antigen (PSA) testing has made the detection of prostate cancer easier in its early stages. Ninety-two out of 100 men get diagnosed when the cancer is limited to the prostate. Most men are diagnosed with prostate cancer in their senior years and only 1 out of 36 men die from it. Death from prostate cancer most often happens when cancer has spread (metastasized) to other organs in the body. This is known as the advanced stage of prostate cancer. The chances of survival decrease as cancer spreads beyond the prostate. If cancer has metastasized to other parts of the body, only three out of 10 men will survive for five years after the diagnosis. Cancerous cells may spread to organs other than the site of origin. In the case of prostate cancer, this tendency is decreased, but it can happen. Advanced stage prostate cancer is defined based on the Gleason score, which is based on the TNM staging of cancer. T stands for tumor size, N stands for lymph node involvement and M stands for metastasis. Prostate cancer can kill in the end through metastases that can develop in

Lymph nodes

Bones (particularly lower spine, pelvis, and femur)

Brain

Liver

Lungs

Metastasis to the bone can cause too much bone calcium to be released into the blood. The condition is known as hypercalcemia. Hypercalcemia can disrupt the functioning of organs, such as the kidney and heart. In severe cases, high calcium levels can lead to death. Metastasis to the lungs can cause the affected lung to collapse or cause a lung infection that becomes difficult to treat. This can severely decrease the affected person’s ability to draw oxygen into the body. Metastasis to the liver can affect the liver’s ability to filter out toxins from the body. This can eventually lead to jaundice, nausea, loss of appetite and weight loss. Paraneoplastic syndrome associated with prostate cancer may cause symptoms such as neuropathy, difficulty walking, loss of muscle tone, loss of fine motor coordination, memory loss, seizures, sensory loss in the limbs and vertigo or dizziness. Paraneoplastic syndromes are a group of rare disorders that are triggered by an abnormal immune system response to cancerous cells. These cells mostly attack the nerve and the muscle cells throughout the body. Advanced stage cancer leads to malnutrition, which can cause muscle wasting, weight loss and fatigue. It may even repress the healthy immune system to an extent that the person develops fungal infections and sepsis.

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Does an enlarged prostate make you poop more?

An enlarged prostate can affect bowel movement but is not common. The prostate rests under the urinary bladder, just in front of the lower rectum. Because they are so close to one another, it is not unusual for one to affect the other.

The main cause of prostate enlargement is primarily a function of genetics and time. If there is family history of prostate enlargement it is more likely you will experience symptoms related to prostate enlargement. Those over 60 years old are more likely to experience symptoms related to prostate enlargement, though some can experience symptoms as early as their 40s. Usually prostate enlargement happens very gradually as you get older. The prostate is a gland that sits at the bottom of the bladder and wraps around the urethra. The urethra is like a tube, where urine exits through from the bladder to the outside of the body. The prostate glands are part of the male reproductive system. They produce portions of semen (ejaculate) and surround the ducts that carry semen into the urethra during orgasm/ejaculation.

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