Prostate Restored
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What can you not do after prostate surgery?

One month after surgery : Doctors recommend no strenuous activity or heavy lifting for at least one month after surgery. Most people take off work for three to four weeks. If you work from home, you could return to work sooner.

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The Johns Hopkins Hospital performs more of these procedures than almost anywhere else in the world. One of the most common questions they hear from patients: “What should I expect after surgery?” If you’ve been diagnosed with prostate cancer , your doctor will consider many factors before recommending the best treatment. For many men, that may mean a prostatectomy. In this surgery, doctors remove the entire prostate. A prostatectomy takes about two hours. You will be under general anesthesia, so you’ll be completely asleep. During the surgery, your doctor will: At Johns Hopkins, doctors use the latest techniques to perform prostatectomies. There are two approaches surgeons can use when performing a prostatectomy. In both of these approaches, the end goal is the same — remove the prostate and destroy the cancer.

After Prostatectomy: What to Expect

At the hospital : You should expect to be in the hospital for one night. At Johns Hopkins, all rooms on the urology floor are private. Here, nurses help patients get moving shortly after surgery to prevent blood clots and other postoperative risks. First few days at home : After you’re sent home, you might find that regular ibuprofen or acetaminophen will be sufficient pain management for the first few days. If over-the-counter medications aren’t enough, your doctor can help you with alternatives. One week after surgery : After your surgery site heals, your catheter will be removed. This is usually seven to 10 days after surgery. This can easily be done at your doctor’s office. Some people decide to take out their catheter at home. If that’s the case, ask your doctor for instructions first. This is also about the time your surgeon will call you with the final pathology results. He or she will discuss what you should know and whether further treatment is necessary. (Many men do not need any more treatment.) One month after surgery : Doctors recommend no strenuous activity or heavy lifting for at least one month after surgery. Most people take off work for three to four weeks. If you work from home, you could return to work sooner. By one month after surgery, your life should start getting back to normal. Some men experience side effects, including:

Urinary incontinence (urine leaking)

Erectile dysfunction

Recovery from surgery takes time. These side effects are often temporary. However, if they are affecting your quality of life, ask your doctor about options that can help.

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Is Cabbage good for prostate?

An organic compound found in cruciferous vegetables such as broccoli, cabbage and cauliflower can inhibit the growth of prostate cancer cells by activating a specific gene that encodes phosphatase and tensin homolog (PTEN), a tumour-suppressing enzyme.

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© S. Priyadarshini

An organic compound found in cruciferous vegetables such as broccoli, cabbage and cauliflower can inhibit the growth of prostate cancer cells by activating a specific gene that encodes phosphatase and tensin homolog (PTEN), a tumour-suppressing enzyme. This finding may help design novel therapies for prostate and other types of cancers1. An international research team, including a scientist from the Intonation Research Laboratories in Hyderabad, India, set out to explore the roles of PTEN, a protein encoded by the PTEN gene in cancer. The PTEN enzyme has been found to suppress tumours when it accumulates in the cell membrane. In cell-based experiments, the researchers identified that WWP1, a protein found in cells, disrupts the function of the PTEN enzyme by dissociating it from the membrane. This, in turn, triggered a cascade of molecular events that eventually forms invasive tumours. They found that another gene, known as MYC, also initiates tumour growth by regulating the activity of the WWP1-coding gene. When the WWP1-coding gene was deleted, PTEN was reactivated. This inhibited the growth of cancer cells. The organic compound blocked the activity of Wwp1 and restored the function of the Pten enzyme, shrinking prostate tumours significantly in mice. The treated mice remained fit and fertile, suggesting that the compound could emerge as a safe anti-cancer drug.

References

1. Lee, Y. et al. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science 364, eaau0159 (2019)

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