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Is Viagra OK for heart?

myheart.net - Is it safe to take Viagra with my heart medications?

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Sexual activity plays a crucial role in the psychological health and quality of life scores in patients with cardiovascular disease. Unfortunately, intimacy is frequently an issue in patient with cardiovascular disease. The causes of sexual dysfunction following myocardial infarction are multiple and include anxiety, depression, medication effect and vascular insufficiency. Regardless of the cause, the results can be devastating to relationships and the psyche. There are three phosphodiesterase-5 inhibitors currently available in the United States: sildenafil (Viagra), vardenafil (Levitra) and tadalafil (Cialis). For simplicity and because of its name recognition, I will use the trade name Viagra to represent all phosphodiesterase-5 (PDE5) inhibitors even if the studies were completed using one of the other drugs. I do not endorse Viagra above any of the others. Viagra has been shown to be effective in the treatment of erectile dysfunction. Viagra works by increasing the amount of nitric oxide available which enhances erectile function.

So can I take Viagra with my heart medications?

Viagra has been shown to be safe in stable cardiovascular diseases including heart failure, hypertension, and coronary artery disease. Although many have looked, there has been no clear evidence that Viagra is associated with increased rate of heart attacks or cardiovascular events. When Viagra is combined with most blood pressure medicines, there is a small but real additive effect but no change in cardiovascular events. However, when Viagra is combined with doxazosin and tamsulosin, two alpha-blocking medications often used to treat BPH (benign prostate hypertrophy) some patients develop low blood pressures. It is recommended that if these prostate medications are required, the smallest doses of each respective medication should be used. Patients already receiving Viagra and other PDE5 inhibitors for pulmonary hypertension should not receive a second PDE5 for the treatment of erectile dysfunction. On the whole, Viagra can be considered safe with almost all of your cardiac medications. Unfortunately, the combination of Viagra with nitrates should never be considered safe. Together they can cause life threatening hypotension, also known as low blood pressure. Nitrates should not be taken within 24 hours of sildenafil or vardenafil and within 48 hours of tadalafil. I have included a short list of commonly prescribed nitrates to help you avoid them. Nitroglycerin Sublingual nitroglycerin tablets (Nitrostat) Sublingual nitroglycerin spray Nitro patch Nitro paste Isosorbide mononitrate (Imdur, ISMO) Isosorbide dinitrate (Isordil)

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Can Viagra cause blood clots?

Viagra helps stimulate erections by increasing levels of cGMP -- which is also involved in blood clotting. Therefore, by increasing levels of cGMP, Viagra may actually increase the risk of blood clots, according to the researchers.

webmd.com - Mystery of Viagra Deaths Unravels - WebMD

Jan. 9, 2003 -- While looking into the intricacies of blood clotting, researchers stumbled on a finding that may explain the mysterious deaths of a small number of men who took the impotence drug Viagra. Researchers say the drug may actually encourage potentially dangerous blood clots to form in men with certain risk factors, such as hardening of the arteries. Viagra was originally developed as a drug to fight heart disease -- thought to increase blood flow by opening up blood vessels and prevent blood clots. But researchers have now found that the popular impotence drug may do exactly the opposite -- encouraging blood-clotting cells known as platelets to clump together and form clots. Their study appears in the Jan. 10 issue of the journal Cell. During their research, Xiaoping Du and colleagues discovered that the enzyme that Viagra affects in the body to improve erections -- called cGMP -- may be the cause behind the increase in blood clots. Du is associate professor of pharmacology at the University of Illinois at Chicago College of Medicine.