Is 20mg of tadalafil too much?

The maximum dose of Cialis that can be taken in a day is 20 mg. You shouldn't take Cialis more than once a day. In clinical trials, Cialis helped people with ED symptoms for up to 36 hours after their dose. So if you're taking the medication only as needed, you shouldn't have to take it every day.

medicalnewstoday.com - Cialis (tadalafil): Dosage, side effects, how long it lasts, and more

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Cialis can interact with several other medications. It can also interact with certain foods. Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase the number of side effects or make them more severe.

Cialis and other medications

Below is a list of medications that can interact with Cialis. This list doesn’t contain all drugs that may interact with Cialis. Before taking Cialis, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Cialis and nitrates

You shouldn’t take Cialis if you’re taking a medication called a nitrate. This type of drug may be used for chest pain. Taking nitrates along with Cialis can cause a serious decrease in your blood pressure.

Examples of nitrates include:

nitroglycerin

isosorbide mononitrate (Monoket)

isosorbide dinitrate (Isordil)

However, in some cases, you doctor may give you a nitrate: for example, if you have chest pain and your life is at risk, and it’s been at least 48 hours since your last dose of Cialis. After you receive the nitrate, your doctor will likely monitor you to make sure your blood pressure doesn’t drop to an unsafe level.

Cialis and alpha-blockers

Both Cialis and medications called alpha-blockers can cause a decrease in blood pressure. So taking these medications together can cause blood pressure to drop further. If you have benign prostatic hyperplasia (BPH) and are taking a medication called an alpha-blocker, you shouldn’t use Cialis. And if you have erectile dysfunction (ED) and are taking an alpha-blocker, your doctor will likely lower your dose of Cialis.

Examples of alpha-blocker drugs include:

tamsulosin (Flomax)

alfuzosin (Uroxatral)

doxazosin (Cardura)

Before taking Cialis, tell your doctor about any medications that you use, including alpha-blockers.

Cialis and medications that lower blood pressure

Cialis may reduce your blood pressure. So if you’re taking other medications to reduce your blood pressure, using Cialis along with them may cause a larger drop in blood pressure.

Examples of blood pressure medications include:

amlodipine (Norvasc)

metoprolol (Toprol XL, Lopressor)

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enalapril (Vasotec)

Before you start Cialis treatment, tell your doctor if you’re taking any blood pressure drugs. They may give you a lower dose of Cialis or monitor you more often.

Cialis and medications to treat heartburn

If you’re taking Cialis and use antacids to treat heartburn, the antacids may decrease the level of Cialis that your body absorbs. This means that you may not get the full dose of Cialis, so it may not work as well to treat your ED or symptoms of BPH.

Examples of antacids include:

calcium carbonate (Tums)

aluminum hydroxide/magnesium hydroxide (Mylanta)

Before you start using Cialis, tell your doctor if you’re taking antacids. Talk with them about how far apart to take the doses of each drug if you need to use both medications.

Cialis and CYP3A4 inhibitors

Cialis is broken down in your body by an enzyme in your liver called CYP3A4. (An enzyme is a protein that aids chemical changes in your body.) Certain drugs can inhibit (block) this enzyme from working. So if the enzyme is unable to break down Cialis, the level of Cialis in your body may get too high. This can be dangerous and may increase your risk of side effects from Cialis. (For more about side effects, see the “Cialis side effects” section above.)

Examples of medications that can block CYP3A4 from working include:

antifungal drugs, such as: ketoconazole itraconazole (Sporanox)

antibiotic drugs, such as: erythromycin (Ery-Tab)

HIV medications, such as: ritonavir (Norvir)

Before starting Cialis treatment, talk with your doctor about any medications that you’re taking. They’ll be able to determine if the drugs are CYP3A4 inhibitors and if they can interact with Cialis. In some cases, your doctor may recommend a lower dose of Cialis or a different medication to treat your ED, symptoms of BPH, or both.

Cialis and CYP3A4 inducers

Cialis is broken down in your liver by an enzyme called CYP3A4. Certain drugs may induce (increase the activity of) CYP3A4, making it work better or faster than usual. This means that your body may break down Cialis more quickly than it should, so the drug may not affect you.

Examples of drugs that induce CYP3A4 include:

rifampin (Rifadin)

carbamazepine (Tegretol)

phenytoin (Dilantin)

phenobarbital

Before you start to use Cialis, talk with your doctor about any medications that you’re taking. They’ll be able to determine if the drugs are CYP3A4 inducers and if they can interact with Cialis. In some cases, your doctor may recommend a different medication to treat your ED, symptoms of BPH, or both.

Cialis and guanylate cyclase stimulators

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You shouldn’t take Cialis if you’re using a type of drug called a guanylate cyclase stimulator. This kind of medication is used to treat people with pulmonary hypertension (a type of high blood pressure in your lungs). Using a guanylate cyclase stimulator along with Cialis may cause your blood pressure to become dangerously low. An example of a guanylate cyclase stimulator is riociguat (Adempas). This medication can be used to treat pulmonary hypertension (PH) that happens in your arteries of your lungs (pulmonary arterial hypertension) or PH that happens due to a blood clot in your lungs. Before taking Cialis, talk with your doctor about any medications you’re using for pulmonary hypertension. If you’re taking riociguat, they’ll likely recommend a different medication to treat your ED, BPH symptoms, or both.

Cialis and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Cialis. However, you should still check with your doctor or pharmacist before using any of these products while taking Cialis.

Cialis and foods

Here’s some information about how Cialis may interact with alcohol and grapefruit.

Alcohol

Both alcohol and Cialis can decrease your blood pressure. So if you drink alcohol while taking this medication, it’s recommended that you don’t drink too much. This may help prevent your blood pressure from becoming too low. For more information, see the “Cialis and alcohol” section above.

Grapefruit

While you take Cialis, it’s best to avoid eating grapefruit and drinking grapefruit juice. Cialis is broken down in your body by an enzyme in your liver called CYP3A4. Grapefruit blocks that enzyme from working. So if the enzyme is unable to break down Cialis, the level of Cialis in your body may get too high. This can be dangerous and may increase your risk of side effects from Cialis. (For more about side effects, see the “Cialis side effects” section above.)

medicalnewstoday.com - Cialis (tadalafil): Dosage, side effects, how long it lasts, and more

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