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Lymphoma most often spreads to the liver, bone marrow, or lungs. Stage III-IV lymphomas are common, still very treatable, and often curable, depending on the NHL subtype. Stage III and stage IV are now considered a single category because they have the same treatment and prognosis.
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Read More »ON THIS PAGE: You will learn about how doctors describe lymphoma’s location and spread. This is called the stage. Use the menu to see other pages. Staging is a way of describing where NHL is located, if or where it has spread, and whether it is affecting other parts of the body. Doctors use diagnostic tests to find out the cancer’s stage, so staging may not be complete until all of the tests are finished. Knowing the stage helps the doctor recommend what kind of treatment is best and can help predict a patient’s prognosis. There are different stage descriptions for different types of cancer.
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Read More »Progressive/refractory: If the cancer grows larger or spreads while the patient is being treated for the original lymphoma, it is called progressive disease. This is also called refractory NHL. Recurrent/relapsed: Recurrent lymphoma is lymphoma that has come back after treatment. It may return in the area where it first started or in another part of the body. Recurrence may occur shortly after the first treatment or years later. If there is a recurrence, the cancer may need to be staged again (called re-staging) using the system above. This is also called relapsed NHL. The original source for this material is Cheson BD, Fisher RI, Barrington SF, et al.: Recommendations for initial evaluation, staging and response assessment of Hodgkin and non-Hodgkin lymphoma—the Lugano Classification, published in the Journal of Clinical Oncology, September 20, 2014; vol. 32, no. 27: 3059–3067.
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Read More »To determine someone’s prognosis, the doctor may also test how well the person is able to function and carry out daily activities by using a functional assessment scale. The Eastern Cooperative Oncology Group (ECOG) Performance Status or the Karnofsky Performance Scales (KPS) are 2 of those scales. ECOG Performance Status. A lower score indicates a better functional status. Typically, the better someone is able to walk and care for themselves, the better the prognosis. Fully active, able to carry on all pre-disease performance without restriction Restricted in physically strenuous activity but able to walk and carry out light work while standing or sitting, such as light house work or office work Able to walk and capable of all self-care but unable to carry out any work activities; up and about for more than 50% of waking hours Capable of only limited self-care; confined to bed or chair for more than 50% of waking hours Completely disabled; cannot carry out any self-care; totally confined to bed or chair Dead
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