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Is Cocoa good for prostate problems?

Our results show that cocoa polyphenols extracts have an antiproliferative effect on prostate cancer cell growth but not on normal cells, at the highest tested concentration.

qima-lifesciences.com - Effects of cocoa & beta-sitosterol on the growth of prostate ...

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Abstract

Cocoa contains many different types of physiologically active components. It was shown that cocoa beans are rich in specific antioxidants such as flavonoids, catechins, epicatechins and proanthocyanidins. Additionally, beta-sitosterol, the most common phytosterol, may play a protective role in the development of cancer. The aim of this in vitro study was to evaluate the inhibitory effect of different cocoa polyphenols extracts, alone or combined with beta-sitosterol, on two human prostate cancer cell lines (nonmetastatic 22Rv1 cells and metastatic DU145 cells) and a normal human prostate cell line (RWEP-1). A synergy between beta-sitosterol and cocoa polyphenols extract was also researched. Cells were treated independently with five products from 1 to 72 h: (1/) synthetic beta-sitosterol, (2/) a cocoa polyphenols extract supplemented with beta-sitosterol, (3/) three different cocoa polyphenols extracts naturally containing beta-sitosterol. In the experiment, beta-sitosterol was tested from 10(-6) to 10(-3)%; cocoa polyphenols extract supplementation was with 0.72% beta-sitosterol; finally cocoa polyphenols extracts were added to the cells at very low concentrations ranging from 0.001 to 0.2%. The growth and viability of cells were measured using colorimetric assay at 1, 3, 6, 24, 48 and 72 h of treatment. IC50 and IC100 corresponding to the concentration leading to a decrease of 50% and 100% of cell growth were determined. At the highest tested concentration, cocoa polyphenols extracts induced a complete inhibition of growth of metastatic and nonmetastatic cancer cell lines. In addition, cocoa polyphenols extracts were more active against local cancer cells than against metastatic cells. Moreover, at the highest tested concentration, cocoa polyphenols extracts are not effective on a normal prostate cell lines. Beta-sitosterol induced low growth inhibition of both cancer cell line. Cocoa polyphenols extracts, however, were significantly more active and showed a strong and fast inhibition of cell growth than beta-sitosterol alone. No synergy or addition was observed when beta-sitosterol was tested together with the cocoa polyphenols extract. Our results show that cocoa polyphenols extracts have an antiproliferative effect on prostate cancer cell growth but not on normal cells, at the highest tested concentration.

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Do you say weird things after general anesthesia?

menshealth.com - Surgical Anesthesia Leads People to Say Crazy Things - Men's Health

Anyone who's received anesthesia can attest that the medication makes them feel pretty loopy. Although many won't remember their experience, it's fairly common to say some wacky things after waking up. On Reddit, a user asked anesthesiologists to post the funniest things people have said while under gas. One commenter relayed how a patient stroked his arm and said, "You'd make such a great carpet." Then, there's the 17-year-old patient who acted like the recovery room was a frat party. "She seemed really stoic and introverted when I first interviewed her but when I was dropping her in the recovery room she went into total bro mode," one doctor wrote. "She keep [sic] saying everything was fucking lit. She keep [sic] saying let’s party bro and responded to every question with a 'fuck yeah, dude.'”

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Another user, who is not an anesthesiologist, relayed the time his tight-laced grandma insulted her preacher. After waking up from surgery, the older woman asked, "Who the fuck is that ugly son of a bitch?" The target of the verbal attack was a preacher from her church. Understandably, family members love to retell that story. "She never lived that one down. The story was even told at her funeral," the Redditor explained. This content is imported from poll. You may be able to find the same content in another format, or you may be able to find more information, at their web site. One Redditor shared another story that highlights the importance of clear communication, particularly when discussing medical procedures. "My dad’s an anesthesiologist. He was treating a woman, and he said, 'I’m putting you to sleep now,'" the commenter wrote. "She replied with the most horrified look on her face, 'Like a dog?!'”

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