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How does cancer of the prostate make you feel?

While most prostate cancer does not cause any symptoms at all, the symptoms and signs of prostate cancer may include: Frequent urination. Weak or interrupted urine flow or the need to strain to empty the bladder. The urge to urinate frequently at night.

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ON THIS PAGE: You will find out more about body changes and other things that can signal a problem that may need medical care. Use the menu to see other pages. A symptom is something that only the person experiencing it can identify and describe, such as fatigue, nausea, or pain. A sign is something that other people can identify and measure, such as a fever, rash, or an elevated pulse. Together, signs and symptoms can help describe a medical problem. While most prostate cancer does not cause any symptoms at all, the symptoms and signs of prostate cancer may include:

Frequent urination

Weak or interrupted urine flow or the need to strain to empty the bladder

The urge to urinate frequently at night

Blood in the urine

New onset of erectile dysfunction

Pain or burning during urination, which is much less common

Discomfort or pain when sitting, caused by an enlarged prostate

Other noncancerous conditions of the prostate, such as BPH or an enlarged prostate, can cause similar symptoms. Or, the cause of a symptom or sign may be another medical condition that is also not related to cancer. Urinary symptoms also can be caused by an infection of the bladder or other conditions. If cancer has spread outside of the prostate gland, symptoms and signs may include:

Pain in the back, hips, thighs, shoulders, or other bones

Swelling or fluid buildup in the legs or feet

Unexplained weight loss

Fatigue

Change in bowel habits

If you are concerned about any changes you experience, please talk with your doctor. Your doctor will ask how long and how often you have been experiencing the symptom(s), in addition to other questions. This is to help figure out the cause of the problem, called a diagnosis. If cancer is diagnosed, relieving symptoms remains an important part of cancer care and treatment. This may be called "palliative care" or "supportive care." It is often started soon after diagnosis and continued throughout treatment. Be sure to talk with your health care team about the symptoms you experience, including any new symptoms or a change in symptoms. The next section in this guide is Diagnosis. It explains what tests may be needed to learn more about the cause of the symptoms. Use the menu to choose a different section to read in this guide.

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What medications can increase PSA levels?

Official answer Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen, and naproxen. Cholesterol-lowering statins, such as Lipitor (atorvastatin) and Zocor (simvastatin) High blood pressure drugs known as thiazide diuretics. More items... •

Some medications can increase levels of prostate-specific antigen (PSA) in the blood, falsely indicating the presence of prostate cancer.

Medications that may raise PSA levels include:

Betamethasone, a steroid prescribed to reduce inflammation

Testosterone replacement therapy, including Jatenzo, a testosterone capsule for men with certain forms of hypogonadism, a condition that occurs when your sex glands produce little or no sex hormones. Other drugs may lower PSA levels in patients, which may indicate a false-negative result. These include:

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen, and naproxen

Cholesterol-lowering statins, such as Lipitor (atorvastatin) and Zocor (simvastatin)

High blood pressure drugs known as thiazide diuretics

Medications used to treat an enlarged prostate or male pattern baldness, such as Proscar and Propecia (finasteride) and Avodart (dutasteride). Researchers are still looking at how medications affect PSA levels in patients with and without prostate cancer and what this means for screening and PSA testing during cancer treatment.

More on high PSA levels

PSA is considered elevated if it is 4 nanograms per milliliter (ng/mL) of blood or higher. About 25% of men who end up having a prostate biopsy because of increased PSA levels are diagnosed with prostate cancer, according to the National Cancer Institute. In addition to certain medications, noncancerous conditions may also cause increases in PSA, including:

Benign prostatic hyperplasia (an enlarged prostate)

Urinary tract infections

Prostatitis (an inflamed prostate gland).

PSA can also be elevated after a prostate biopsy and prostate surgery.

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