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How do prostate cancer patients die?

Most men are diagnosed with prostate cancer in their senior years and only 1 out of 36 men die from it. Death from prostate cancer most often happens when cancer has spread (metastasized) to other organs in the body. This is known as the advanced stage of prostate cancer.

medicinenet.com - How Does Prostate Cancer Kill You in the End? - MedicineNet

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Prostate cancer is cancer of the prostate gland in men. Death from prostate cancer most often happens when cancer has spread (metastasized) to other organs in the body. Prostate cancer is the most common cancer after skin cancer in men in the US and the second leading cause of cancer death. Prostate-specific antigen (PSA) testing has made the detection of prostate cancer easier in its early stages. Ninety-two out of 100 men get diagnosed when the cancer is limited to the prostate. Most men are diagnosed with prostate cancer in their senior years and only 1 out of 36 men die from it. Death from prostate cancer most often happens when cancer has spread (metastasized) to other organs in the body. This is known as the advanced stage of prostate cancer. The chances of survival decrease as cancer spreads beyond the prostate. If cancer has metastasized to other parts of the body, only three out of 10 men will survive for five years after the diagnosis. Cancerous cells may spread to organs other than the site of origin. In the case of prostate cancer, this tendency is decreased, but it can happen. Advanced stage prostate cancer is defined based on the Gleason score, which is based on the TNM staging of cancer. T stands for tumor size, N stands for lymph node involvement and M stands for metastasis. Prostate cancer can kill in the end through metastases that can develop in

Lymph nodes

Bones (particularly lower spine, pelvis, and femur)

Brain

Liver

Lungs

Metastasis to the bone can cause too much bone calcium to be released into the blood. The condition is known as hypercalcemia. Hypercalcemia can disrupt the functioning of organs, such as the kidney and heart. In severe cases, high calcium levels can lead to death. Metastasis to the lungs can cause the affected lung to collapse or cause a lung infection that becomes difficult to treat. This can severely decrease the affected person’s ability to draw oxygen into the body. Metastasis to the liver can affect the liver’s ability to filter out toxins from the body. This can eventually lead to jaundice, nausea, loss of appetite and weight loss. Paraneoplastic syndrome associated with prostate cancer may cause symptoms such as neuropathy, difficulty walking, loss of muscle tone, loss of fine motor coordination, memory loss, seizures, sensory loss in the limbs and vertigo or dizziness. Paraneoplastic syndromes are a group of rare disorders that are triggered by an abnormal immune system response to cancerous cells. These cells mostly attack the nerve and the muscle cells throughout the body. Advanced stage cancer leads to malnutrition, which can cause muscle wasting, weight loss and fatigue. It may even repress the healthy immune system to an extent that the person develops fungal infections and sepsis.

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How long is life expectancy with advanced prostate cancer?

Once prostate cancer has spread beyond the prostate, survival rates fall. For men with distant spread (metastasis) of prostate cancer, about one-third will survive for five years after diagnosis.

webmd.com - Prostate Cancer Survival Rates: What They Mean - WebMD

As cancer diagnoses go, prostate cancer is often a less serious one. Prostate cancer is frequently slow-growing and slow to spread. For many men, prostate cancer is less serious than their other medical conditions. For these reasons, and possibly because of earlier detection of low-grade prostate cancers, prostate cancer has one of the highest survival rates of any type of cancer. WebMD takes a look at prostate cancer survival rates and what they mean to you. Prostate Cancer Is Common With Aging After skin cancer, prostate cancer is the most common cancer in men. About 1 in 7 men will be diagnosed with prostate cancer in their lifetime. And these are just the men who are diagnosed. Among very elderly men dying of other causes, a surprising two-thirds may have prostate cancer that was never diagnosed. Only 1 in 36 men, though, actually dies from prostate cancer. That's because most prostate cancers are diagnosed in older men in whom the disease is more likely to be slow-growing and non-aggressive. The majority of these men eventually pass away from heart disease, stroke, or other causes -- not their prostate cancer.

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