Photo: Ann H

How common is Noonan syndrome?

It's estimated that between 1 in 1,000 and 1 in 2,500 children are born with Noonan syndrome. It affects both sexes and all ethnic groups equally. Read more about the characteristics of Noonan syndrome and diagnosing Noonan syndrome.

nhs.uk - Noonan syndrome - NHS

When during the day is blood pressure highest?

Blood pressure has a daily pattern. Usually, blood pressure starts to rise a few hours before a person wakes up. It continues to rise during the...

Last updated Aug 12, 2022

Can sperm go through 1 layers clothing?

Pregnancy Myth #5: Can sperm travel through clothing or material? If the clothing was completely saturated with semen and was in direct contact...

Last updated Oct 21, 2021

Promotion

Noonan syndrome is a genetic condition that can cause a wide range of distinctive features and health problems. The condition is present from before birth, although milder cases may not be diagnosed until a child gets older. The most common features of Noonan syndrome are: unusual facial features, such as a broad forehead, drooping eyelids and a wider-than-usual distance between the eyes

short stature (restricted growth)

heart defects (congenital heart disease) It's estimated that between 1 in 1,000 and 1 in 2,500 children are born with Noonan syndrome. It affects both sexes and all ethnic groups equally. Read more about the characteristics of Noonan syndrome and diagnosing Noonan syndrome. What causes Noonan syndrome? Noonan syndrome is caused by a fault in one of several genes. At least 8 different faulty genes have been linked to the condition so far. In some cases, the faulty gene associated with Noonan syndrome is inherited from one of the child's parents. The parent with the faulty gene may or may not have obvious features of the condition themselves. Only one parent needs to carry the fault to pass it on and each child they have has a 50% chance of being born with the condition. In other cases, the condition is caused by a new genetic fault that isn't inherited from either parent. In these cases, the chance of the parents having another child with Noonan syndrome is very small. Read more about the causes of Noonan syndrome. Treatments for Noonan syndrome There's currently no single treatment for Noonan syndrome, but it's often possible to successfully manage many aspects of the condition. For example, severe heart defects may need to be repaired with surgery, and growth hormone medicine may be used to help prevent restricted growth. Your child may need quite a lot of treatment and support to help manage the various problems they have. However, they'll usually need much less care as they get older, because the condition tends to cause fewer problems in adulthood. Read more about treating Noonan syndrome. Outlook Noonan syndrome can range from being very mild to severe and life-threatening. In many cases, the problems associated with the condition can be successfully treated at a young age or become less prominent over time. Almost all children with Noonan syndrome reach adulthood and most are able to lead normal, independent lives. However, problems such as heart defects can occasionally be severe and life-threatening. Some children may need emergency surgery to correct the problem as soon as possible, and most people with Noonan syndrome will need to have their heart monitored regularly throughout their life. Noonan Syndrome Association If you or your child has been diagnosed with Noonan syndrome, you may find the Noonan Syndrome Association a useful source of support and advice. The charity Newlife, which helps families with disabled children, runs a free nurse helpline you can call – – for more information. National Congenital Anomaly and Rare Disease Registration Service If your child has Noonan syndrome, your clinical team will pass information about them on to the National Congenital Anomaly and Rare Disease Registration Service (NCARDRS). This helps scientists look for better ways to prevent and treat Noonan syndrome. You can opt out of the register at any time.

Can stress cause cancer?

Stress can speed up the spread of cancer throughout the body, especially in ovarian, breast and colorectal cancer. When the body becomes stressed,...

Last updated Jun 3, 2021

How to tell the difference between enlarged prostate and prostate cancer?

The percentage of free PSA can help tell what kind of prostate problem you have. If both total PSA and free PSA are higher than normal (high...

Last updated Sep 10, 2021

Promotion

How common is Waardenburg syndrome?

Waardenburg syndrome affects an estimated 1 in 40,000 people. It accounts for 2 to 5 percent of all cases of congenital hearing loss. Types I and II are the most common forms of Waardenburg syndrome, while types III and IV are rare.

medlineplus.gov - Waardenburg syndrome: MedlinePlus Genetics

Waardenburg syndrome is a group of genetic conditions that can cause hearing loss and changes in coloring (pigmentation) of the hair, skin, and eyes. Although most people with Waardenburg syndrome have normal hearing, moderate to profound hearing loss can occur in one or both ears. The hearing loss is present from birth (congenital). People with this condition often have very pale blue eyes or different colored eyes, such as one blue eye and one brown eye. Sometimes one eye has segments of two different colors. Distinctive hair coloring (such as a patch of white hair or hair that prematurely turns gray) is another common sign of the condition. The features of Waardenburg syndrome vary among affected individuals, even among people in the same family. There are four recognized types of Waardenburg syndrome, which are distinguished by their physical characteristics and sometimes by their genetic cause. Types I and II have very similar features, although people with type I almost always have eyes that appear widely spaced and people with type II do not. In addition, hearing loss occurs more often in people with type II than in those with type I. Type III (sometimes called Klein-Waardenburg syndrome) includes abnormalities of the arms and hands in addition to hearing loss and changes in pigmentation. Type IV (also known as Waardenburg-Hirschsprung disease or Waardenburg-Shah syndrome) has signs and symptoms of both Waardenburg syndrome and Hirschsprung disease, an intestinal disorder that causes severe constipation or blockage of the intestine.

What is prostate cancer pain like?

Sciatica is the most common type of referred pain in advanced prostate cancer. It's caused by damage to one or more of the nerves that start in the...

Last updated Dec 12, 2020