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Does pumpkin have side effects?

Side effects from pumpkin products are rare, but might include stomach discomfort, diarrhea, and nausea. It might also cause itching, rash, and allergic reactions in some people.

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Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. View abstract. Carbin BE, Larsson B, Lindahl O. Treatment of benign prostatic hyperplasia with phytosterols. Br J Urol 1990;66:639-41. View abstract. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. View abstract. Coulson S, Rao A, Beck SL, Steels E, Gramotnev H, Vitetta L. A phase II randomised double-blind placebo-controlled clinical trial investigating the efficacy and safety of ProstateEZE Max: a herbal medicine preparation for the management of symptoms of benign prostatic hypertrophy. Complement Ther Med 2013;21(3):172-9. View abstract. De Bellis L, Gonzali S, Alpi A, et al. Purification and characterization of a novel pumpkin short-chain acyl-coenzyme A oxidase with structural similarity to acyl-coenzyme A dehydrogenases. Plant Physiol 2000;123:327-34. View abstract. Durante M, Lenucci MS, Mita G. Supercritical carbon dioxide extraction of carotenoids from pumpkin (Cucurbita spp.): a review. Int J Mol Sci 2014;15(4):6725-40. View abstract. Foster S, Tyler VE. Tyler's Honest Herbal, 4th ed., Binghamton, NY: Haworth Herbal Press, 1999. Friederich M, Theurer C, Schiebel-Schlosser G. [Prosta Fink Forte capsules in the treatment of benign prostatic hyperplasia. Multicentric surveillance study in 2245 patients]. Forsch Komplementarmed Klass Naturheilkd 2000;7:200-4. View abstract. Gauruder-Burmester A, Heim S, Patz B, Seibt S. Cucurbita pepo-Rhus aromatica-Humulus lupulus combination reduces overactive bladder symptoms in women - a noninterventional study. Planta Med. 2019;85(13):1044-53. View abstract. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. View abstract. Ibrahim IM, Hasan MS, Elsabaa KI, Elsaie ML. Pumpkin seed oil vs. minoxidil 5% topical foam for the treatment of female pattern hair loss: A randomized comparative trial. J Cosmet Dermatol 2021 Feb 5. doi: 10.1111/jocd.13976. View abstract. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. View abstract. Medjakovic S, Hobiger S, Ardjomand-Woelkart K, Bucar F, Jungbauer A. Pumpkin seed extract: cell growth inhibition of hyperplastic and cancer cells, independent of steroid hormone receptors. Fitoterapia 2016;110:150-6. View abstract. Shirvan MK, Mahboob MR, Masuminia M, Mohammadi S. Pumpkin seed oil (prostafit) or prazosin? Which one is better in the treatment of symptomatic benign prostatic hyperplasia. J Pak Med Assoc 2014;64(6):683-5. View abstract. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95. View abstract. Younis YM, Ghirmay S, al-Shihry SS. African Cucurbita pepo L.: properties of seed and variability in fatty acid composition of seed oil. Phytochemistry 2000;54:71-5. View abstract. Zerafatjou N, Amirzargar M, Biglarkhani M, Shobeirian F, Zoghi G. Pumpkin seed oil (Cucurbita pepo) versus tamsulosin for benign prostatic hyperplasia symptom relief: a single-blind randomized clinical trial. BMC Urol 2021;21(1):147. View abstract. Zhang X, Ouyang JZ, Zhang YS, et al. Effect of the extracts of pumpkin seeds on the urodynamics of rabbits: an experimental study. J Tongji Med Univ 1994;14:235-8. View abstract.

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Do cashews raise uric acid?

Cashews Put to the Test They found that people who consumed 20 percent of their daily calories in the form of unsalted cashews had no significant change in their blood uric acid levels. So if you are on a low purine diet, you can most likely eat cashews daily without worry of rising uric acid levels.

You may benefit from a low purine diet if you have gout. Uric acid is a byproduct of purine breakdown in the blood. If uric acid gets too high in your blood, it can crystallize and accumulate in your joints causing a painful gout attack. If you are on a low purine diet, it is good to know that cashew nuts in moderation are a healthy food choice.

Low Purines, No Worries

A low purine diet is basically a healthy diet, according to Arthritis Today, and includes all the food groups, especially vegetables, whole grains, low-fat dairy and plant proteins such as nuts, beans and legumes while limiting your intake of processed foods and refined carbohydrates.

What the Academy Says

Although purine content is not specified on food labels, the Academy of Nutrition and Dietetics categorizes plant proteins as having either low or moderate purine content on its Nutrition Care Manual. While it categorizes beans and lentils as medium purine foods that should be limited to 1 cup cooked daily, it clears nuts, including cashews, as low purine and states you can eat any amount on a low purine diet.

Cashews Put to the Test

Researchers of a study published in "The British Journal of Nutrition" in 2007, wanted to test the impact of a diet high in unsalted cashews on different markers of the metabolic syndrome -- uric acid levels in the blood was one of these markers. They found that people who consumed 20 percent of their daily calories in the form of unsalted cashews had no significant change in their blood uric acid levels. So if you are on a low purine diet, you can most likely eat cashews daily without worry of rising uric acid levels.

But Are They Beneficial?

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