Prostate Restored
Prostate Restored
Photo: George Milton
“This study proves that if a man's going to live 20-25 years and he's got intermediate prostate cancer, he has an opportunity to save his life,” D'Amico said. According to the study, those men who had a radical prostatectomy at the start of the study lived an average of 2.9 years longer than men who got no therapy.
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Read More »Nearly 30 years after it began, a study of prostate cancer patients shows both that the disease will not cause harm to the majority of men who have it, and that aggressive treatment is warranted for men with an intermediate risk of spread. The nuanced results come from a new update to a landmark study, published Wednesday in the New England Journal of Medicine, that has followed 695 Swedish men since they were diagnosed with localized prostate cancer between October 1989 and February 1999. The study’s duration and insights into one of the most common forms of cancer make it “arguably one of the most important publications of the year,” said Dr. Adam Kibel, a professor of surgery at Harvard Medical School and chief of urology at Brigham and Women’s Hospital in Boston, who is not involved in the research.
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Read More »“This study proves that if a man’s going to live 20-25 years and he’s got intermediate prostate cancer, he has an opportunity to save his life,” D’Amico said. According to the study, those men who had a radical prostatectomy at the start of the study lived an average of 2.9 years longer than men who got no therapy. But that really means more men in the treatment group were able to live out their natural lives, while men who got watchful waiting died early, D’Amico said. D’Amico also highlighted what he called “a pretty striking statistic”: that just eight men needed to undergo treatment to save one life, according to the study. For comparison, 233 women in their 60s would need to get a mammogram to prevent one of those woman from dying of breast cancer, according to a 2012 study. Newsletters Sign up for Morning Rounds Your daily dose of news in health and medicine. Please enter a valid email address. Privacy Policy Leave this field empty if you're human: Kibel, the Brigham and Women’s urologist, said the Swedish study has been “central to our understanding of how we manage prostate cancer,” for decades, and confirms that many patients benefit from aggressive treatment. The Swedish study was started so long ago that men didn’t routinely get PSA tests to diagnose prostate cancer, as they often do today. Routine PSA screening can overdiagnose cancers that won’t turn lethal. But combined with their Gleason score — and maybe someday with a diagnostic MRI — men should be able to figure out whether their cancer is advanced enough to warrant treatment, or to monitor it to make sure it isn’t turning more aggressive, Bill-Axelson said. A man’s health and his disease risk — not his age — should be the determining factors in whether he should be treated for prostate cancer, Bill-Axelson said. When asked whether an 80-year-old should be treated, she said, only half-joking: “If he comes with his parents, it’s a good idea.”
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