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Can I take Flomax and Cialis together?

This study examined whether combining tadalafil (Cialis) and tamsulosin (Flomax) can reduce both urinary symptoms as well as erectile dysfunction. This treatment combination was safe and effective in reducing urinary symptoms and improving erectile function.

medivizor.com - Combining flomax and cialis can effectively treat urinary symptoms ...

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Posted by Medivizor on Sep 27, 2017 in Benign prostatic hyperplasia |

In a nutshell

Some background

Many men with benign prostatic hyperplasia (BPH) experience both urinary symptoms as well as erectile dysfunction. One report found that 72.2% of men with urinary symptoms due to BPH also had erectile dysfunction. Only 37.7% had urinary symptoms without some form of erectile dysfunction. Tamsulosin is a type of alpha-blocker commonly prescribed for urinary symptoms. It works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate. Tadalafil is a type of phosphodiesterase-5 inhibitor developed for erectile dysfunction. It increases blood flow to the penis and it also helps to relax muscle cells in the bladder and prostate. Both tamsulosin alone and tadalafil alone are commonly used to treat each condition separately. Whether they are safe and effective when combined is still under investigation.

Methods & findings

This study included 510 men with BPH. All men reported urinary symptoms as well as erectile dysfunction. Men were randomly assigned to treatment groups. 153 men were treated with high-dose tamsulosin (0.4 mg) plus tadalafil (5 mg). 164 men were treated with low-dose tamsulosin (0.2 mg) plus tadalafil (5 mg). 162 men were treated with tadalafil alone (5 mg). Treatment outcomes were compared between groups at 12 weeks. Men treated with the 0.4/5 mg combination showed significantly better improvements in urinary symptoms compared to men treated with tadalafil alone. Both groups improved erectile function. The change in urinary symptoms among men treated with the 0.2/5 mg combination was not superior when compared to tadalafil alone. No significant difference in the rate of side effects was observed between groups. 14.11% of men treated with the 0.4/5 mg combination reported side effects. It was 8.43% among men treated with the 0.2/5 mg combination and 5.85% in the group receiving tadalafil alone. Common side effects included headache, nasal congestion, and flushing. Only 0.6 and 1.8% of men reported serious side effects.

The bottom line

This study concluded that the combination of 0.4 mg of tamsulosin and 5 mg of tadalafil reduced urinary symptoms as well as erectile dysfunction safely and effectively in men with BPH.

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Do you take Flomax for life?

Tamsulosin is generally safe to take for a long time. In fact, it works best when you take it for a long time. What will happen if I stop taking it? Stopping tamsulosin suddenly can make your condition worse as your symptoms may return.

nhs.uk - Tamsulosin: a medicine used to treat men with symptoms of an ... - NHS

Tamsulosin comes as slow-release tablets and capsules (also called modified release, prolonged release, MR or XL).

This means the medicine is released into your body gradually.

How much will I take?

The usual dose of tamsulosin for enlarged prostate and kidney stone is 400 micrograms, once a day. The word microgram is sometimes written with the Greek symbol μ followed by the letter g (μg). A microgram is 1,000 times smaller than a milligram (mg).

How to take it

Swallow your tamsulosin capsules or tablets whole with a glass of water.

Do not break, chew or crush them.

If you can, take tamsulosin in the morning, after breakfast or the first meal or snack of the day. This is so the highest levels of medicine are in your body during the day and gives you the most benefit when you are most likely trying to pee.

It's best to take it at about the same time each day.

What if I forget to take it?

If you miss a dose of tamsulosin, and you remember within 6 hours, take the missed dose as soon as you remember. If it's more than 6 hours, skip the missed dose and take your next dose at the usual time the next day. Do not take a double dose to make up for a forgotten dose. If you forget doses often, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine.

What if I take too much?

Taking too much tamsulosin can lead to a decrease in your blood pressure and an increase in your heart rate. You may feel drowsy, faint and lightheaded.

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