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Can 2 blue eyed parents produce green eyes?

First, the answer is yes to both questions: two blue-eyed parents can produce green or brown-eyed children. Eye color is not the simple decision between the brown (or green) and blue versions of a single gene. There are many genes involved and eye color ranges from brown to hazel to green to blue to…

thetech.org - Can two blue-eyed parents have a green or brown-eyed child?

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These are excellent questions. People are often very confused by eye color genetics because reality seems to fly in the face of the simple genetics we are taught in school. First, the answer is yes to both questions: two blue-eyed parents can produce green or brown-eyed children. Eye color is not the simple decision between the brown (or green) and blue versions of a single gene. There are many genes involved and eye color ranges from brown to hazel to green to blue to… Eye color comes from a combination of two black and yellow pigments called melanin in the iris of your eye. If you have no melanin in the front part of your iris, you have blue eyes. An increasing proportion of the yellow melanin, in combination with the black melanin, results in shades of colors between brown and blue, including green and hazel. What we are taught in high school biology is generally true: brown eye genes are dominant over green eye genes which are both dominant over blue eye genes. However, because many genes are required to make each of the yellow and black pigments, there is a way called genetic complementation to get brown or green eyes from blue-eyed parents.

Genetic complementation

The best way to illustrate how this might happen is with an example. Let's say there is a genetic pathway made up of four genes (cleverly named A, B, C, and D) that are needed to make brown eyes. And as I am sure you know, we have two copies of each of these genes, one inherited from our mom and one from our dad A mutation in both copies of any one of these genes results in blue eyes (these mutations are denoted with lower case letters, a, b, c, and d). If either parent gives you a brown version of a gene, it will be dominant over the blue copy. Now let's say that dad has blue eyes because of a mutation in both his copies of gene A:

aa BB CC DD

And mom has blue eyes because of a mutation in both her copies of gene D:

AA BB CC dd

Now let’s suppose they have a child. They’ll pass on one gene from each pair, like this: In this case, you would inherit a brown A from mom and a blue a from dad. And a brown D from dad and a blue d from mom. You would be: Aa BB CC Dd What color eyes would you have? Brown. Remember, you need two recessive (lower case) versions in the same gene to have blue eyes.

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The same logic works for green eyes as well. If your parents have blue eyes due to different genes, you can easily get unexpected results like this.

Recombination

Another common genetic process that could be responsible for brown eyes from blue-eyed parents is called recombination. When eggs and sperm are made, only one of a pair of chromosomes gets put into an egg or sperm. Before this happens, there is a bunch of DNA swapping that goes on between the pair of chromosomes. Sometimes when the DNA is swapped or recombined, DNA mutations get fixed. Again, an example can show how this might work. Imagine dad has blue eyes because of a mutation at the front end of one copy of his eye color gene and a different mutation at the back end of the other copy of the gene. Each gene has a single mutation but at different places in the gene. Now imagine that when his sperm is being made, the middle part of the eye color gene is switched between the two genes resulting in one brown eye gene and one blue eye gene with two mutations. Now dad can produce a brown-eyed child.

Again, the same argument works for a green eye gene as well.

Environmental influence

Another way to get brown eyes from blue-eyed parents is for something in the environment to affect the eye color gene. Even though there are well-documented cases in which this happens, the reasons for it are pretty poorly understood. There are cases, for example, of certain drugs changing a person's eye color -- the environment clearly has changed what happened to eye color in this case. Another possibility is that a gene is on or off for some reversible reason instead of an irreversible change in DNA. In this case, something in the environment reverses the change, turning the eye color gene back on or off. Well, I hope this helped answer your question. As you can see it is all pretty complicated. It would be great if high school biology classes would stop confusing us by teaching eye color as a single trait.

thetech.org - Can two blue-eyed parents have a green or brown-eyed child?

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